1.1.1.30 761858 beta-Hydroxybutyrate dehydrogenase decorated MXene nanosheets for the amperometric determination of beta-hydroxybutyrate Microchim. Acta 187 277 2020 Paucimonas lemoignei http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32314063&form=6&db=m 1.1.1.30 760246 Dissecting the mechanism of (R)-3-hydroxybutyrate dehydrogenase by kinetic isotope effects, protein crystallography, and computational chemistry ACS Catal. 10 15019-15032 2020 Acinetobacter baumannii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33391858&form=6&db=m 1.1.1.30 760246 Dissecting the mechanism of (R)-3-hydroxybutyrate dehydrogenase by kinetic isotope effects, protein crystallography, and computational chemistry ACS Catal. 10 15019-15032 2020 Psychrobacter arcticus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33391858&form=6&db=m 1.1.1.30 760246 Dissecting the mechanism of (R)-3-hydroxybutyrate dehydrogenase by kinetic isotope effects, protein crystallography, and computational chemistry ACS Catal. 10 15019-15032 2020 Psychrobacter arcticus DSM 17307 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33391858&form=6&db=m 1.1.1.30 286512 (R)-3-Hydroxybutyrate dehydrogenase: selective phosphatidylcholine binding by the C-terminal domain Biochemistry 39 11929-11938 2000 Homo sapiens - 1.1.1.30 738207 3-Hydroxybutyrate dehydrogenase-2 and ferritin-H synergistically regulate intracellular iron FEBS J. 281 2410-2421 2014 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24673886&form=6&db=m 1.1.1.30 729048 3-Hydroxybutyrate oligomer hydrolase and 3-hydroxybutyrate dehydrogenase participate in intracellular polyhydroxybutyrate and polyhydroxyvalerate degradation in Paracoccus denitrificans Appl. Environ. Microbiol. 80 986-993 2014 Paracoccus denitrificans http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24271169&form=6&db=m 1.1.1.30 729048 3-Hydroxybutyrate oligomer hydrolase and 3-hydroxybutyrate dehydrogenase participate in intracellular polyhydroxybutyrate and polyhydroxyvalerate degradation in Paracoccus denitrificans Appl. Environ. Microbiol. 80 986-993 2014 Paracoccus denitrificans ATCC 17741 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24271169&form=6&db=m 1.1.1.30 286523 3-Hydroxyisobutyrate dehydrogenase, an impurity in commercial 3-hydroxybutyrate dehydrogenase Biochem. J. 241 297-300 1987 Cereibacter sphaeroides http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3494445&form=6&db=m 1.1.1.30 286527 A rapid and efficient procedure for the purification of mitochondrial beta-hydroxybutyrate dehydrogenase Biochim. Biophys. Acta 815 51-56 1985 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3986202&form=6&db=m 1.1.1.30 656326 Biochemical and genetic characterization of a D(-)-3-hydroxybutyrate dehydrogenase from Acidovorax sp. strain SA1 J. Biosci. Bioeng. 97 78-81 2004 Acidovorax sp. http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16233594&form=6&db=m 1.1.1.30 689351 Biochemical and histological alterations of cellular metabolism from jerboa (Jaculus orientalis) by 2,4-dichlorophenoxyacetic acid: Effects on D-3-hydroxybutyrate dehydrogenase Pestic. Biochem. Physiol. 90 87-96 2008 Jaculus orientalis - 1.1.1.30 286541 Characterization and partial purification of beta-hydroxybutyrate dehydrogenase from sporulating cells of Bacillus cereus T Can. J. Microbiol. 19 673-677 1973 Bacillus cereus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4197242&form=6&db=m 1.1.1.30 286541 Characterization and partial purification of beta-hydroxybutyrate dehydrogenase from sporulating cells of Bacillus cereus T Can. J. Microbiol. 19 673-677 1973 Bacillus cereus T http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4197242&form=6&db=m 1.1.1.30 695653 Characterization of a novel 3-hydroxybutyrate dehydrogenase from Ralstonia pickettii T1 Antonie van Leeuwenhoek 95 249-262 2009 Ralstonia pickettii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19219638&form=6&db=m 1.1.1.30 695653 Characterization of a novel 3-hydroxybutyrate dehydrogenase from Ralstonia pickettii T1 Antonie van Leeuwenhoek 95 249-262 2009 Ralstonia pickettii T1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19219638&form=6&db=m 1.1.1.30 669434 Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenase J. Biol. Chem. 281 10291-10297 2006 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16380372&form=6&db=m 1.1.1.30 669544 Characterization of two 3-hydroxybutyrate dehydrogenases in poly(3-hydroxybutyrate)-degradable bacterium, Ralstonia pickettii T1 J. Biosci. Bioeng. 101 501-507 2006 Ralstonia pickettii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16935252&form=6&db=m 1.1.1.30 669544 Characterization of two 3-hydroxybutyrate dehydrogenases in poly(3-hydroxybutyrate)-degradable bacterium, Ralstonia pickettii T1 J. Biosci. Bioeng. 101 501-507 2006 Ralstonia pickettii T1 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16935252&form=6&db=m 1.1.1.30 668322 Characterization of two D-b-hydroxybutyrate dehydrogenase populations in heavy and light mitochondria from jerboa (Jaculus orientalis) liver Comp. Biochem. Physiol. B 143B 285-293 2006 Jaculus orientalis - 1.1.1.30 698660 Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor J. Biochem. 145 467-479 2009 Pseudomonas fragi http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19122202&form=6&db=m 1.1.1.30 286521 Comparison of 3-hydroxybutyrate dehydrogenase from bovine heart and rat liver mitochondria Arch. Biochem. Biophys. 262 85-98 1988 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3355176&form=6&db=m 1.1.1.30 286521 Comparison of 3-hydroxybutyrate dehydrogenase from bovine heart and rat liver mitochondria Arch. Biochem. Biophys. 262 85-98 1988 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3355176&form=6&db=m 1.1.1.30 679792 Cosubstrate-induced dynamics of D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida FEBS J. 274 5767-5779 2007 Pseudomonas putida http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17958702&form=6&db=m 1.1.1.30 667070 Crystallization and preliminary X-ray characterization of D-3-hydroxybutyrate dehydrogenase from Pseudomonas fragi Acta Crystallogr. Sect. F 61 36-38 2005 Pseudomonas fragi http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16508084&form=6&db=m 1.1.1.30 286525 Cyanylation of 3-hydroxybutyrate dehydrogenase Biol. Chem. Hoppe-Seyler 367 343-353 1986 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3013239&form=6&db=m 1.1.1.30 286529 D-3-Hydroxybutyrate dehydrogenase and metabolism of ketone bodies by rat stomach Biochem. Soc. Trans. 607 788 1984 Rattus norvegicus - 1.1.1.30 669873 D-3-hydroxybutyrate dehydrogenase from Pseudomonas fragi: molecular cloning of the enzyme gene and crystal structure of the enzyme J. Mol. Biol. 355 722-733 2006 Pseudomonas fragi http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16325199&form=6&db=m 1.1.1.30 737912 Effect of His-tag location on the catalytic activity of 3-hydroxybutyrate dehydrogenase Biotechnol. Bioprocess Eng. 19 798-802 2014 Alcaligenes faecalis - 1.1.1.30 286517 Effect of selective thiol-group derivatization on enzyme kinetics of (R)3-hydroxybutyrate dehydrogenase Biochem. J. 296 563-569 1993 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8280053&form=6&db=m 1.1.1.30 721853 Enzymatic reduction of levulinic acid by engineering the substrate specificity of 3-hydroxybutyrate dehydrogenase Biores. Technol. 134 377-380 2013 Alcaligenes faecalis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23489571&form=6&db=m 1.1.1.30 655126 Hibernation impact on the catalytic activities of the mitochondrial D-3-hydroxybutyrate dehydrogenase in liver and brain tissues of jerboa (Jaculus orientalis) BMC Biochem. 4 11 2003 Jaculus orientalis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12964952&form=6&db=m 1.1.1.30 737467 Identification and characterization of genes, encoding the 3-hydroxybutyrate dehydrogenase and a putative lipase, in an avirulent spontaneous Legionella pneumophila serogroup 6 mutant APMIS 123 330-341 2015 Legionella pneumophila subsp. pneumophila http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25556866&form=6&db=m 1.1.1.30 737467 Identification and characterization of genes, encoding the 3-hydroxybutyrate dehydrogenase and a putative lipase, in an avirulent spontaneous Legionella pneumophila serogroup 6 mutant APMIS 123 330-341 2015 Legionella pneumophila subsp. pneumophila DSM 7513 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25556866&form=6&db=m 1.1.1.30 739558 Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy Proc. Natl. Acad. Sci. USA 113 E1460-E1469 2016 Danio rerio http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26929344&form=6&db=m 1.1.1.30 286532 Inhibition of bacterial D-3-hydroxybutyrate dehydrogenase by substrates and substrate analogues Can. J. Biochem. 59 810-815 1981 Paucimonas lemoignei http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7317814&form=6&db=m 1.1.1.30 286540 Inhibition of D(-)-3-hydroxybutyrate dehydrogenase by malonate analoges Arch. Biochem. Biophys. 166 164-173 1975 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1122131&form=6&db=m 1.1.1.30 286540 Inhibition of D(-)-3-hydroxybutyrate dehydrogenase by malonate analoges Arch. Biochem. Biophys. 166 164-173 1975 Cavia porcellus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1122131&form=6&db=m 1.1.1.30 286540 Inhibition of D(-)-3-hydroxybutyrate dehydrogenase by malonate analoges Arch. Biochem. Biophys. 166 164-173 1975 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1122131&form=6&db=m 1.1.1.30 286528 Inhibition of D(-)-beta-hydroxybutyrate dehydrogenase by butanedione, phenylglyoxal, and diethyl pyrocarbonate Biochemistry 20 459-463 1981 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7213590&form=6&db=m 1.1.1.30 286535 Inhibition of D(-)-beta-hydroxybutyrate dehydrogenase by modifiers of disulfides, thiols, and vicinal dithiols Biochemistry 20 453-458 1981 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7213589&form=6&db=m 1.1.1.30 286518 Inhibition of succinate dehydrogenase and beta-hydroxybutyrate dehydrogenase activities by methylmalonate in brain and liver of developing rats J. Inherit. Metab. Dis. 16 147-153 1993 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8487494&form=6&db=m 1.1.1.30 680512 Isolated poly(3-hydroxybutyrate) (PHB) granules are complex bacterial organelles catalyzing formation of PHB from acetyl coenzyme A (CoA) and degradation of PHB to acetyl-CoA J. Bacteriol. 189 8250-8256 2007 Cupriavidus necator http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17720797&form=6&db=m 1.1.1.30 286524 Kinetics of D-3-hydroxybutyrate dehydrogenase from Paracoccus denitrificans Biochim. Biophys. Acta 871 302-309 1986 Paracoccus denitrificans - 1.1.1.30 286542 Mitochondrial D-beta-hydroxybutyrate dehydrogenase. III. Isolation and characterization J. Biol. Chem. 248 2549-2555 1973 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4633355&form=6&db=m 1.1.1.30 286543 Mitochondrial D-beta-hydroxybutyrate dehydrogenase. IV. Kinetic analysis of reaction mechanism J. Biol. Chem. 248 2556-2562 1973 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4349040&form=6&db=m 1.1.1.30 668251 Molecular basis of substrate recognition in D-3-hydroxybutyrate dehydrogenase from Pseudomonas putida ChemBioChem 7 1410-1418 2006 Pseudomonas putida http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16888731&form=6&db=m 1.1.1.30 286519 Molecular cloning and characterization of (R)3-hydroxybutyrate dehydrogenase from human heart J. Biol. Chem. 267 15459-15463 1992 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1639787&form=6&db=m 1.1.1.30 286516 Monoclonal antibodies for structure-function studies of (R)-3-hydroxybutyrate dehydrogenase, a lipid-dependent membrane-bound enzyme Biochem. J. 292 863-872 1993 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7686368&form=6&db=m 1.1.1.30 286516 Monoclonal antibodies for structure-function studies of (R)-3-hydroxybutyrate dehydrogenase, a lipid-dependent membrane-bound enzyme Biochem. J. 292 863-872 1993 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7686368&form=6&db=m 1.1.1.30 286522 Noncooperative vs. cooperative reactivation of D-beta-hydroxybutyrate dehydrogenase: multiple equilibria for lecithin binding are determined by the physical state (soluble vs. bilayer) and composition of the phospholipids Biochemistry 26 5283-5293 1987 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3676253&form=6&db=m 1.1.1.30 286522 Noncooperative vs. cooperative reactivation of D-beta-hydroxybutyrate dehydrogenase: multiple equilibria for lecithin binding are determined by the physical state (soluble vs. bilayer) and composition of the phospholipids Biochemistry 26 5283-5293 1987 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3676253&form=6&db=m 1.1.1.30 286515 Occurence, purification and properties of the staphylococcal beta-hydroxybutyrate dehydrogenase Acta Microbiol. Pol. 43 33-45 1994 Staphylococcus xylosus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7526614&form=6&db=m 1.1.1.30 286520 Post-transcriptional analysis of rat mitochondrial D-3-hydroxybutyrate dehydrogenase control through development and physiological stages Biol. Cell. 73 121-129 1991 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1804504&form=6&db=m 1.1.1.30 685409 Prehibernation and hibernation effects on the D-3-hydroxybutyrate dehydrogenase of the heavy and light mitochondria from liver jerboa (Jaculus orientalis) and related metabolism Biochimie 89 1019-1028 2007 Jaculus orientalis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17531367&form=6&db=m 1.1.1.30 655261 Purification and characterization of the D-beta-hydroxybutyrate dehydrogenase from dromedary liver mitochondria Comp. Biochem. Physiol. B 131 9-18 2002 Camelus dromedarius http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11742753&form=6&db=m 1.1.1.30 286539 Purification and properties of beta-hydroxybutyrate dehydrogenase from Mycobacterium phlei ATCC354 J. Gen. Microbiol. 104 123-126 1978 Mycolicibacterium phlei http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24083&form=6&db=m 1.1.1.30 286526 Purification and properties of D-3-hydroxybutyrate dehydrogenase from Paracoccus denitrificans Biochim. Biophys. Acta 839 300-307 1985 Paracoccus denitrificans - 1.1.1.30 286534 Purification and properties of D-beta-hydroxybutyrate dehydrogenase from Zoogloea ramiger I-16-M J. Biochem. 89 625-635 1981 Zoogloea ramigera I-16-M http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7240131&form=6&db=m 1.1.1.30 286533 Selective interaction of D-beta-hydroxybutyrate dehydrogenase with intracellular membranes Biochim. Biophys. Acta 641 222-231 1981 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7213714&form=6&db=m 1.1.1.30 286514 Specific interaction of(R)-3-hydroxybutyrate dehydrogenase with membrane phosphatidylcholine as studied by ESR spectroscopy in oriented phospholipid multilayers: coenzyme binding enhances the interaction with phosphatidylcholine Biochemistry 35 3044-3049 1996 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8608144&form=6&db=m 1.1.1.30 711807 Structural and catalytic properties of the D-3-hydroxybutyrate dehydrogenase from Pseudomonas aeruginosa Curr. Microbiol. 61 7-12 2010 Pseudomonas aeruginosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20052585&form=6&db=m 1.1.1.30 737914 Structural basis for the substrate specificity of 3-hydroxybutyrate dehydrogenase Biotechnol. Bioprocess Eng. 21 364-372 2016 Alcaligenes faecalis - 1.1.1.30 737394 Structural insights into the catalytic reaction trigger and inhibition of D-3-hydroxybutyrate dehydrogenase Acta Crystallogr. Sect. F 72 507-515 2016 Alcaligenes faecalis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27380367&form=6&db=m 1.1.1.30 695376 Structure of D-3-hydroxybutyrate dehydrogenase prepared in the presence of the substrate D-3-hydroxybutyrate and NAD+ Acta Crystallogr. Sect. F 65 331-335 2009 Alcaligenes faecalis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19342772&form=6&db=m 1.1.1.30 286537 Substrate analogue studies of the specificity and catalytic mechanism of D-3-hydroxybutyrate dehydrogenase J. Am. Chem. Soc. 100 7388-7392 1978 Paucimonas lemoignei - 1.1.1.30 286530 Target size of D-beta-hydroxybutyrate dehydrogenase J. Biol. Chem. 258 953-959 1983 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6822516&form=6&db=m 1.1.1.30 286536 The kinetics of rat liver and heart mitochondria beta-hydroxybutyrate dehydrogenase Biochem. J. 179 579-581 1979 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=475768&form=6&db=m 1.1.1.30 286538 The orientation of D-beta-hydroxybutyrate dehydrogenase in the mitochondrial inner membrane Biochim. Biophys. Acta 513 255-267 1978 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=718894&form=6&db=m 1.1.1.30 286531 The rapid purification of 3-hydroxybutyrate dehydrogenase and malate dehydrogenase on triazine dye affinity matrices Biochem. J. 203 699-705 1982 Cereibacter sphaeroides http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6981412&form=6&db=m 1.1.1.30 684149 The structures of Alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase before and after NAD+ and acetate binding suggest a dynamical reaction mechanism as a member of the SDR family Acta Crystallogr. Sect. D 64 496-505 2008 Alcaligenes faecalis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18453685&form=6&db=m 1.1.1.30 286513 Wild type and mutant human heart (R)-3-hydroxybutyrate dehydrogenase expressed in insect cells Biochemistry 35 8158-8165 1996 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8679568&form=6&db=m 1.1.1.30 286513 Wild type and mutant human heart (R)-3-hydroxybutyrate dehydrogenase expressed in insect cells Biochemistry 35 8158-8165 1996 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8679568&form=6&db=m