2.5.1.75 676732 Characterisation of a prokaryote-type tRNA-isopentenyltransferase gene from the moss Physcomitrella patens Planta 226 683-695 2007 Physcomitrium patens https://pubmed.ncbi.nlm.nih.gov/17450376/ 2.5.1.75 489967 Cloning of a human tRNA isopentenyl transferase Gene 258 85-93 2000 Homo sapiens https://pubmed.ncbi.nlm.nih.gov/11111046/ 2.5.1.75 705984 Crystal structure and substrate specificity of plant adenylate isopentenyltransferase from Humulus lupulus: distinctive binding affinity for purine and pyrimidine nucleotides Nucleic Acids Res. 38 1738-1748 2010 Humulus lupulus https://pubmed.ncbi.nlm.nih.gov/20007608/ 2.5.1.75 700955 Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA: insight into tRNA recognition and reaction mechanism Proc. Natl. Acad. Sci. USA 105 16142-16147 2008 Saccharomyces cerevisiae https://pubmed.ncbi.nlm.nih.gov/18852462/ 2.5.1.75 489959 DELTA 2 -isopentenylpyrophosphate: transfer ribonucleic acid 2 -isopentenyltransferase from Escherichia coli. Purification and properties of the enzyme J. Biol. Chem. 247 5675-5680 1972 Escherichia coli https://pubmed.ncbi.nlm.nih.gov/4341485/ 2.5.1.75 696190 Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: a binding mechanism for recombinant enzyme Biochemistry 36 604-614 1997 Escherichia coli https://pubmed.ncbi.nlm.nih.gov/9012675/ 2.5.1.75 696195 Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: essential elements for recognition of tRNA substrates within the anticodon stem-loop Biochemistry 39 6546-6553 2000 Escherichia coli https://pubmed.ncbi.nlm.nih.gov/10828971/ 2.5.1.75 696197 Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: site-directed mutagenesis of highly conserved residues Biochemistry 40 1734-1740 2001 Escherichia coli https://pubmed.ncbi.nlm.nih.gov/11327834/ 2.5.1.75 686911 Expression of a human tRNA isopentenyltransferase in tobacco reveals a developmental role for tRNA isopentenyladenosine Funct. Plant Biol. 34 654-661 2007 Homo sapiens - 2.5.1.75 660174 Expression of cytokinin biosynthetic isopentenyltransferase genes in Arabidopsis: tissue specificity and regulation by auxin, cytokinin, and nitrate Plant J. 37 128-138 2004 Arabidopsis thaliana https://pubmed.ncbi.nlm.nih.gov/14675438/ 2.5.1.75 706187 Expression of isopentenyl transferase gene (ipt) in leaf and stem delayed leaf senescence without affecting root growth Plant Cell Rep. 28 1759-1765 2009 Agrobacterium tumefaciens https://pubmed.ncbi.nlm.nih.gov/19820948/ 2.5.1.75 706146 Flower-specific expression of the Agrobacterium tumefaciens isopentenyltransferase gene results in radial expansion of floral organs in Petunia hybrida Plant Biotechnol. J. 6 694-701 2008 Agrobacterium tumefaciens https://pubmed.ncbi.nlm.nih.gov/18482222/ 2.5.1.75 660041 Identification and functional characterization of the candidate tumor suppressor gene TRIT1 in human lung cancer Oncogene 24 5502-5509 2005 Homo sapiens https://pubmed.ncbi.nlm.nih.gov/15870694/ 2.5.1.75 489963 Identification of a tRNA isopentenyltransferase gene from Arabidopsis thaliana Plant Mol. Biol. 49 161-169 2002 Arabidopsis thaliana https://pubmed.ncbi.nlm.nih.gov/11999372/ 2.5.1.75 759655 Light influences cytokinin biosynthesis and sensing in Nostoc (cyanobacteria) J. Phycol. 53 703-714 2017 Nostoc sp. PCC 7120 = FACHB-418 https://pubmed.ncbi.nlm.nih.gov/28378335/ 2.5.1.75 737635 Mammalian Trit1 is a tRNA([Ser]Sec)-isopentenyl transferase required for full selenoprotein expression Biochem. J. 450 427-432 2013 Mus musculus https://pubmed.ncbi.nlm.nih.gov/23289710/ 2.5.1.75 706864 Molecular cloning of a putative gene encoding isopentenyltransferase from pingyitiancha (Malus hupehensis) and characterization of its response to nitrate Tree Physiol. 28 899-904 2008 Malus hupehensis https://pubmed.ncbi.nlm.nih.gov/18381270/ 2.5.1.75 489960 N6-(2-isopentenyl) adenosine: biosynthesis in vitro in transfer RNA by an enzyme purified from Escherichia coli Biochimie 54 31-39 1972 Escherichia coli https://pubmed.ncbi.nlm.nih.gov/4346747/ 2.5.1.75 489958 N6-(delta-2-isopentenyl) adenosine. Biosynthesis in transfer ribonucleic acid in vitro Biochemistry 8 4361-4371 1969 Saccharomyces cerevisiae https://pubmed.ncbi.nlm.nih.gov/4311031/ 2.5.1.75 758624 Noninvasive diagnosis of TRIT1-related mitochondrial disorder by measuring i6 A37 and ms2 i6 A37 modifications in tRNAs from blood and urine samples Am. J. Med. Genet. A 179 1609-1614 2019 Homo sapiens https://pubmed.ncbi.nlm.nih.gov/31140736/ 2.5.1.75 723760 Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases RNA 17 1846-1857 2011 Schizosaccharomyces pombe https://pubmed.ncbi.nlm.nih.gov/21873461/ 2.5.1.75 723760 Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases RNA 17 1846-1857 2011 Saccharomyces cerevisiae https://pubmed.ncbi.nlm.nih.gov/21873461/ 2.5.1.75 723760 Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases RNA 17 1846-1857 2011 Homo sapiens https://pubmed.ncbi.nlm.nih.gov/21873461/ 2.5.1.75 489966 Regulation of physiological rates in Caenorhabditis elegans by a tRNA-modifying enzyme in the mitochondria Genetics 159 147-157 2001 Caenorhabditis elegans https://pubmed.ncbi.nlm.nih.gov/11560893/ 2.5.1.75 489965 Regulation of substrate recognition by the MiaA tRNA prenyltransferase modification enzyme of Escherichia coli K-12 J. Biol. Chem. 272 13073-13083 1997 Escherichia coli https://pubmed.ncbi.nlm.nih.gov/9148919/ 2.5.1.75 676830 Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis Proc. Natl. Acad. Sci. USA 103 16598-16603 2006 Arabidopsis thaliana https://pubmed.ncbi.nlm.nih.gov/17062755/ 2.5.1.75 737708 Steady-state kinetics and spectroscopic characterization of enzyme-tRNA interactions for the non-heme diiron tRNA-monooxygenase, MiaE Biochemistry 54 363-376 2015 Salmonella enterica https://pubmed.ncbi.nlm.nih.gov/25453905/ 2.5.1.75 737708 Steady-state kinetics and spectroscopic characterization of enzyme-tRNA interactions for the non-heme diiron tRNA-monooxygenase, MiaE Biochemistry 54 363-376 2015 Salmonella enterica ATCC 700720 https://pubmed.ncbi.nlm.nih.gov/25453905/ 2.5.1.75 689971 Structural bioinformatics analysis of enzymes involved in the biosynthesis pathway of the hypermodified nucleoside ms2io6A37 in tRNA Proteins 70 1-18 2008 Salmonella enterica subsp. enterica serovar Typhimurium https://pubmed.ncbi.nlm.nih.gov/17910062/ 2.5.1.75 760010 Targeting mitochondrial and cytosolic substrates of TRIT1 isopentenyltransferase Specificity determinants and tRNA-i6A37 profiles PLoS Genet. 16 e1008330 2020 Homo sapiens https://pubmed.ncbi.nlm.nih.gov/32324744/ 2.5.1.75 489964 Transfer RNA is the source of extracellular isopentenyladenine in a Ti-plasmidless strain of Agrobacterium tumefaciens Plant Physiol. 110 431-438 1996 Agrobacterium tumefaciens https://pubmed.ncbi.nlm.nih.gov/12226194/ 2.5.1.75 489968 Transfer RNA recognition by the Escherichia coli D2-isopentenyl-pyrophosphate:tRNA D2-isopentenyl transferase: dependence on the anticodon arm structure RNA 3 721-733 1997 Escherichia coli https://pubmed.ncbi.nlm.nih.gov/9214656/ 2.5.1.75 489961 tRNA isopentenyltransferase from Lactobacillus acidophilus ATCC 4963 Hoppe-Seyler's Z. Physiol. Chem. 356 1459-1464 1975 Lactobacillus acidophilus https://pubmed.ncbi.nlm.nih.gov/809333/ 2.5.1.75 489962 tRNA isopentenyltransferase from Zea mays L. Characterization of the isopentenylation reaction of tRNA, oligo (A) and other nucleic acids Hoppe-Seyler's Z. Physiol. Chem. 359 89-101 1978 Zea mays https://pubmed.ncbi.nlm.nih.gov/342386/