5.1.1.21	L-isoleucine = D-allo-isoleucine	-	-	
5.1.1.21	L-isoleucine = D-allo-isoleucine	L-isoleucine epimerization proceeds through abstraction of the alpha-hydrogen of the substrate by Lys280, while Asp222 serves as the catalytic residue adding an alpha-hydrogen to the quinonoid intermediate to form D-allo-isoleucine, structure-function relationship	746630	
5.1.1.21	L-isoleucine = D-allo-isoleucine	the racemization reaction by the fold-type I racemases may generally occur thanks to a revised two-base mechanism. Conformational changes provoked by pyridoxal 5'-phosphate binding suggesting an induced fit of the active site entrance door necessary to accommodate pyridoxal 5'-phosphate and substrate molecules	-, 747208