4.4.1.11 L-methionine + H2O = methanethiol + NH3 + 2-oxobutanoate mechanism 4.4.1.11 L-methionine + H2O = methanethiol + NH3 + 2-oxobutanoate cleavage of C-N bond in addition to C-S, C-Se and C-O bond at beta-position of amino acids by elimination and replacement reactions 4.4.1.11 L-methionine + H2O = methanethiol + NH3 + 2-oxobutanoate rate determining stage of the enzymatic reaction is deamination of aminocrotonate, important contribution of the sulfur atom and methylene groups to the efficiency of binding of substrates and inhibitors 4.4.1.11 L-methionine + H2O = methanethiol + NH3 + 2-oxobutanoate gamma-elimination reaction mechanism and intermediates, overview