3.4.23.43	medicine	the pathogenicity island PAPI-1 may have evolved by acquisition of a conjugation system but because of its dependence on an essential chromosomal determinant, its transfer is restricted to Pseudomonas aeruginosa or other species capable of providing a functional prepilin peptidase	717727	
3.4.23.43	synthesis	scaled-up synthesis of PilD, followed by solubilization in dodecyl-beta-D-maltoside and chromatography, leads to a pure enzyme that retains its known biochemical activities	-, 734649