2.5.1.66	synthesis	clavulanic acid intermediates: deoxygaunidinoproclavaminic acid, guanidinoproclavaminic acid, and dihydroclavaminic acid are heterologously produced in Streptomyces venezuelae recombinant using four sets of early genes from the clavulanic acid biosynthetic pathway	742159	
2.5.1.66	synthesis	in an industrial clavulanic acid-overproducer Streptomyces clavuligerus DEPA, carboxyethylarginine synthase (Ceas2), clavaldehyde dehydrogenase (Car) and carboxyethyl-arginine betalactam synthase (Bls2) are overrepesented, whereas the enzymes of two other secondary metabolites are underrepresented	760210	
2.5.1.66	synthesis	synthesis of clavulanic acid intermediates in Streptomyces venezuelae by expression of clavulanic acid biosynthesis genes carboxyethylarginine synthase (Ceas2), beta-lactam synthetase (Bls2), clavaminate synthase (Cas2), and proclavaminate amidinohydrolase (Pah2). The recombinant strain produces deoxygaunidinoproclavaminic acid, guanidinoproclavaminic acid, and dihydroclavaminic acid	742159