1.1.1.304 synthesis acetoin(diacetyl) reductase, i.e. 2,3-butanediol dehydrogenase, is one of the key enzymes in the microbial production of 2,3-butanediol, a platform with extensive industrial applications in the production of plastics, printing inks, perfumes, fumigants, spandex, moistening and softening agents, plasticizers, and pharmaceutical carrier -, 721396 1.1.1.304 synthesis the enzyme is used for production of S-acetoin with higher than 99.9% optical purity from diacetyl using whole cells of engineered Escherichia coli -, 725854