2.7.8.13	analysis	the enzyme is an attractive antibacterial drug target involved in peptidoglycan synthesis	-, 737580	
2.7.8.13	drug development	antibacterial chemotherapy against pathogenic bacteria being multiresistant to common antibiotics	690996	
2.7.8.13	drug development	biological activity of uridine moiety in naturally occurring non-specific MraY inhibitors (like liposidomycins and caprazamycins), antibacterial chemotherapy against pathogenic bacteria being multiresistant to common antibiotics	692188	
2.7.8.13	drug development	the specificity of the enzyme to eubacteria makes it a promising potential target to be exploited for antibacterial discovery to combat emerging resistance	-, 737788	
2.7.8.13	medicine	opportunistic pathogen causing infections in patients with burns or neutropenia and involved in respiratory tract infections of cystic fibrosis patients, pathway of peptidoglycan biosynthesis is both essential and unique to bacteria, making it an attractive target for antibiotic research	645342	
2.7.8.13	medicine	target for antimicrobial therapeutic intervention, novel antibiotic chemotypes must be developed to deter the alarming rate of antibiotic resistance growth	645343	
2.7.8.13	medicine	the enzyme is a potential target for antibacterial compounds	660721	
2.7.8.13	medicine	translocase I is a target of antibiotics	704218, 704219	
2.7.8.13	molecular biology	synthesis of radiolabelled UDP-MurNAc-pentapeptide as biochemical tools for studying peptidoglycan biosynthesis or the kinetic characterization of MraY	695173	
2.7.8.13	synthesis	heterologous production of enzyme in Escherichia coli membranes into styrene-maleic acid-wrapped nanodiscs and purification using detergent-free styrene-maleic acid copolymer system. Yield and the purity of the recombinant protein are comparable to enzyme extracted with a conventional detergent. The predominantly alpha-helical secondary structure of the protein in SMA-wrapped nanodiscs is more stable against heat denaturation compared to the micellar protein	-, 762243	
2.7.8.13	synthesis	the enzyme is an attractive antibacterial drug target involved in peptidoglycan synthesis	-, 737580