2.8.2.34 3'-phosphoadenylyl 5'-phosphosulfate + dehydroepiandrosterone - 2.8.2.34 3'-phosphoadenylyl 5'-phosphosulfate + glycochenodeoxycholate - 2.8.2.34 3'-phosphoadenylyl 5'-phosphosulfate + lithocholate - 2.8.2.34 additional information the enzyme is involved in prevention of toxicity of monohydroxy bile acids 2.8.2.34 additional information the sulfation reaction may be a protective mechanism against the hepatotoxic effects of some bile acids in facilitating the excretion