2.1.2.8	5,10-methylenetetrahydrofolate + H2O + dCMP	-	
2.1.2.8	5,10-methylenetetrahydrofolate + H2O + deoxycytidylate	-	
2.1.2.8	5,10-methylenetetrahydrofolate + H2O + deoxycytidylate	dCTP depresses the synthesis of 5-hydroxymethyldeoxycytidylate	
2.1.2.8	5,10-methylenetetrahydrofolate + H2O + deoxycytidylate	the hydroxymethylation is catalyzed by dCMP hydroxymethylase, which transfers a methylene group from methylenetetrahydrofolate to C5 of dCMP and then uses a water molecule to hydrate the methylene group to form hydroxymethyl-dCMP, one precursor for phage DNA replication	
2.1.2.8	additional information	enzyme is part of the dNTP synthetase complex	
2.1.2.8	additional information	enzyme functions in vivo as a component of a multienzyme complex called dNTP synthetase	
2.1.2.8	additional information	enzyme is part of a complex efficiently channeling DNA precursors to the replication apparatus	
2.1.2.8	additional information	biosynthesis of enzyme de novo after infection	
2.1.2.8	additional information	enzyme is part of a complex catalyzing DNA precursor biosynthesis	
2.1.2.8	additional information	direct interaction between NDP kinase and dCMP hydroxymethylase