1.14.14.20	2,4-dichlorophenol + FADH2 + O2	-	
1.14.14.20	2-chlorophenol + FADH2 + O2	poor substrate for isozyme PheA1(1)	
1.14.14.20	4-chlorophenol + FADH2 + O2	-	
1.14.14.20	4-methylphenol + FADH2 + O2	-	
1.14.14.20	additional information	enzyme components PheA2 and PheA1 show no protein-protein interaction	
1.14.14.20	additional information	substrate speccificities of the three isozymes, overview	
1.14.14.20	phenol + FADH2 + O2	-	
1.14.14.20	phenol + FADH2 + O2	a two-component enzyme system: the smaller flavin reductase PheA2 component catalyzes the NADH-dependent reduction of free FAD according to a ping pong bisubstrate-biproduct mechanism. The reduced FAD is then used by the larger oxygenase component PheA1 to hydroxylate phenols to the corresponding catechols	
1.14.14.20	phenol + NADPH + O2	first step of phenol degradation