1.13.11.85 cis-1,4-polyisoprene + n O2 - 1.13.11.85 cis-1,4-polyisoprene + O2 - 1.13.11.85 cis-1,4-polyisoprene + O2 Gram-negative rubber-degrading bacteria generally utilise two synergistically acting rubber oxygenases (RoxA/RoxB) for efficient cleavage of polyisoprene to (4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal 1.13.11.85 rubber latex + O2 the enzyme is excreted by Xanthomonas to functionalize and cleave the inert latex biopolymer poly(cis-1,4-isoprene) into the more soluble (4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal units