3.5.1.98	alpha-tubulin + H2O	splicing variant HDAC6p114 is intact in its deacetylase activity against a-tubulin	
3.5.1.98	alpha-tubulin + H2O	-	
3.5.1.98	additional information	conserved mechanism of histone deacetylase repression of some secondary metabolite gene clusters	
3.5.1.98	additional information	histone deacetylases regulate the expression of HoxA9, which acts as a master switch to regulate the expression of prototypical endothelial-committed genes such as endothelial nitric oxide synthase, VE-cadherin, VEGF-R2, and mediates the shear stress-induced maturation of endothelial cells	
3.5.1.98	additional information	isoform HDAC4 is an essential regulator of myofibroblastic differentiation	
3.5.1.98	additional information	isoforms HDAC1 and HDAC2 are associated in vivo, complex is able to deacetylate all four core histones in vitro	
3.5.1.98	additional information	acetylation of histone core proteins is regulated by HDAC, H3K9-K14 deacetylation is mediated, at least in part, by HDAC 11	
3.5.1.98	additional information	deacetylation of tubulin	
3.5.1.98	additional information	HDAC6 deacetylases tubulins, best noted substrate is beta-tubulin	
3.5.1.98	additional information	HDACs catalyse the removal of acetyl groups from e-N-acetylated lysine residues of various protein substrates