2.7.4.9 ATP + dTMP - 2.7.4.9 ATP + thymidine - 2.7.4.9 ATP + TMP - 2.7.4.9 L-dTMP + ATP - 2.7.4.9 ATP + dTMP involved in dTTP metabolism, essential for cell proliferation 2.7.4.9 ATP + TMP involved in TTP metabolism 2.7.4.9 ATP + dTMP involved in TTP metabolism, required for the activation of clinically relevant thymidine analogs such as anti-HIV and anti-cancer prodrugs 2.7.4.9 additional information key enzyme in nucleotide synthesis 2.7.4.9 additional information multifunctional enzyme which also phosphorylates pyrimidine nucleosides, pyrimidine nucleoside monophosphates, and several nucleoside analogues 2.7.4.9 ATP + dTMP reaction in both the de novo and salvage pathways of dTTP synthesis