3.4.22.40	bleomycin + H2O	-	
3.4.22.40	bleomycin + H2O	bleomycin is a cytotoxic agent inducing pneumonitis, detoxification reaction	
3.4.22.40	bleomycin + H2O	detoxification reaction	
3.4.22.40	bleomycin + H2O	detoxification reaction, high enzyme expression level leads to resistance against the drug	
3.4.22.40	bleomycin A2 + H2O	the enzyme hydrolyzes bleomycins into the biologically inactive deamido bleomycins	
3.4.22.40	bleomycin B2 + H2O	the enzyme hydrolyzes bleomycins into the biologically inactive deamido bleomycins	
3.4.22.40	deiminated filaggrin + H2O	neutral cysteine protease bleomycin hydrolase is essential for the breakdown of deiminated filaggrin into amino acids	
3.4.22.40	homocysteine-thiolactone + H2O	-	
3.4.22.40	huntingtin + H2O	the enzyme is involved in a specific cleavage step at the N-terminal fragment cp-2 site of huntingtin	
3.4.22.40	L-homocysteine-thiolactone + H2O	-	
3.4.22.40	additional information	the enzyme exhibits protection against homocysteine toxicity, role and mechanisms of bleomycin hydrolase, overview	
3.4.22.40	additional information	the enzyme expression is regulated by galactose and Gal4p,expression pattrern	
3.4.22.40	additional information	role in generating MHC class I-presented peptides suggested	
3.4.22.40	additional information	bleomycin hydrolase does not hydrolyze D-Hcy-thiolactone	
3.4.22.40	Z-Leu-Leu-Glu-NH-4-nitroanilide + H2O	no activity in vitro due to requirement of binding to DNA-recognition sites of ztranscriptional activator Gal4p