2.7.6.1	ATP + D-ribose 5-phosphate	-	
2.7.6.1	ATP + D-ribose 5-phosphate	the product phosphoribosyldiphosphate is required for the biosynthesis of purine, pyrimidine and pyridine nucleotides, L-histidine and L-tryptophan	
2.7.6.1	ATP + D-ribose 5-phosphate	the enzymatic activity of PRS is regulated by both the activator phosphate and the inhibitor ADP competing for binding at a common allosteric regulatory site	
2.7.6.1	D-ribose 5-phosphate + ATP	PRPP (phosphoribosylpyrophosphate) synthetases are a family of enzymes that catalyse the synthesis of PRPP from ATP and R5P (ribose 5-phosphate) by transferring the beta, gamma-diphosphoryl moiety of ATP to the C1-hydroxy group of R5P.	
2.7.6.1	D-ribose 5-phosphate + ATP	biosynthesis of purines and pyrimidines	
2.7.6.1	additional information	the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis	
2.7.6.1	ribose-5-phosphate + ATP	first step in purine metabolic pathway