2.3.1.39 acetyl-CoA + an [acyl-carrier protein] - 2.3.1.39 malonyl-CoA + acyl-carrier protein initial reaction in de novo fatty acid synthesis, part of non-associated fatty acid synthase system of plants and prokaryotes 2.3.1.39 malonyl-CoA + acyl-carrier protein the enzyme is a component of the fatty acid synthetase system 2.3.1.39 malonyl-CoA + an [acyl-carrier protein] - 2.3.1.39 malonyl-CoA + an [acyl-carrier protein] the wild type enzyme is highly specific for malonyl-CoA 2.3.1.39 malonyl-CoA + [acyl-carrier protein] - 2.3.1.39 malonyl-CoA + [acyl-carrier protein] absolutely specific for the substrates, type II [acyl-carrier protein] 2.3.1.39 malonyl-CoA + [acyl-carrier protein] enzyme is involved in both fatty acid and polyketide synthesis pathways 2.3.1.39 malonyl-CoA + [acyl-carrier protein] enzyme provides acyl-ACP thioesters for the biosynthesis of aromatic polyketides, overview, and thus is the primary gatekeeper of substrate specificity in type II polyketide synthase 2.3.1.39 malonyl-CoA + [acyl-carrier protein] key enzyme in fatty acid synthesis 2.3.1.39 additional information the enzyme is responsible for charging the tetracenomycin M acyl-carrier-protein with malonate in vivo, a key step in the synthesis of the deca(polyketide) precursor of tetracenomycin C. This implies the existence of a functional connection between fatty acid and polyketide metabolism in this bacterium 2.3.1.39 additional information enzyme is part of the malonyl-CoA-dependent type II fatty acid synthase complex in mitochondria 2.3.1.39 additional information enzyme is part of the malonyl-CoA-dependent type II fatty acid synthase complex in mitochondria, reaction sequence of the involved enzymes, overview