1.14.14.17	additional information	the enzyme activity is associated with cytochrome P450 17alpha hydroxylase/17,20 lyase CYP17 in cholesterol biosynthesis in Leydig cells	
1.14.14.17	additional information	the enzyme affects morphogenesis and drug susceptibilities	
1.14.14.17	additional information	Arabidopsis thaliana squalene epoxidase 1 is essential for root and seed development	
1.14.14.17	additional information	squalene epoxidase interacts with NADPH-cytochrome P450 reductase and a second microsomal reductase for the conversion of squalene to 2,3(s)-oxidosqualene and to lanosterol in the cholesterol biosynthesis pathway, overview	
1.14.14.17	squalene + AH2 + O2	rate-limiting step in chloesterol biosynthesis	
1.14.14.17	squalene + AH2 + O2	-	
1.14.14.17	squalene + AH2 + O2	oxidosqualene or dioxidosqualene appears to be the branching point for primary metabolism and secondary metabolites in basidiomycetes	
1.14.14.17	squalene + AH2 + O2	production of the precursor for all known angiosperm cyclic triterpenoids, which include membrane sterols, brassinosteroid phytohormones, and non-steroidal triterpenoids, overview	
1.14.14.17	squalene + AH2 + O2	rate-limiting enzyme in the triterpene saponins biosynthetic pathway, overview	
1.14.14.17	squalene + AH2 + O2	the enzyme is involved in ergosterol biosynthesis	
1.14.14.17	squalene + electron donor + O2	first oxygenase and last nonsterol reaction of sterol biosynthesis	
1.14.14.17	squalene + electron donor + O2	may be rate-limiting step in cholesterol biosynthesis in non-cholesterogenic tissues	
1.14.14.17	squalene + O2 + AH2	-	
1.14.14.17	squalene + reduced acceptor + O2	epoxidation of squalene is the first step in cholesterol biosynthesis	
1.14.14.17	squalene + reduced cytochrome P450 + O2	first step in the cyclic chloesterol biosynthesis	
1.14.14.17	squalene + [reduced NADPH-hemoprotein reductase] + O2	-