2.7.7.53 Ca2+ 2 mM, 38% of the activity with Mn2+ 739577 2.7.7.53 Ca2+ 2 mM, 43% of the activity with Mn2+ 739577 2.7.7.53 Ca2+ activates 643515 2.7.7.53 Ca2+ as good as Mn2+ 209909, 643508 2.7.7.53 Ca2+ less effective than Co2+ 209909 2.7.7.53 Ca2+ less effective than Mg2+ 209909, 643507 2.7.7.53 Ca2+ requirement, less effective than Mn2+ 643507 2.7.7.53 Ca2+ Rv2613c requires bivalent metal ions such as Ca2+ to exert its Ap4A phosphorylase activity (64% activity in the presence of 2 mM Ca2+) 713455 2.7.7.53 Cd2+ slight activation 209909, 643507 2.7.7.53 Co2+ 2 mM, 60% of the activity with Mn2+ 739577 2.7.7.53 Co2+ 2 mM, 89% of the activity with Mn2+ 739577 2.7.7.53 Co2+ activates 643515 2.7.7.53 Co2+ activation, less effective than Mn2+ or Ca2+ or Mg2+ 209909, 643507 2.7.7.53 Co2+ Rv2613c requires bivalent metal ions such as Co2+ to exert its Ap4A phosphorylase activity (68% activity in the presence of 2 mM Co2+) 713455 2.7.7.53 Co2+ slight activation of P1,P4-bis(5'-adenosyl) tetraphosphate-synthesis 643508 2.7.7.53 divalent metal cations requirement 209909, 643507, 643513 2.7.7.53 Mg2+ - 209909 2.7.7.53 Mg2+ 2 mM, 97% of the activity with Mn2+ 739577 2.7.7.53 Mg2+ 2 mM, 98% of the activity with Mn2+ 739577 2.7.7.53 Mg2+ activation, P1,P4-bis(5'-adenosyl) tetraphosphate-synthesis 643508 2.7.7.53 Mg2+ inhibitory in presence of phosphate for ADP/phosphate exchange reaction 643514 2.7.7.53 Mg2+ less effective than Mn2+ or Ca2+ 643508 2.7.7.53 Mg2+ required 643507, 760256 2.7.7.53 Mg2+ required, most effective divalent cation 643515 2.7.7.53 Mg2+ Rv2613c requires bivalent metal ions such as Mg2+ to exert its Ap4A phosphorylase activity (34% activity in the presence of 2 mM Mg2+) 713455 2.7.7.53 Mn2+ 10 mM 209909 2.7.7.53 Mn2+ 2 mM, best divalent activator 739577 2.7.7.53 Mn2+ activates 643515 2.7.7.53 Mn2+ less effective than Mg2+ or Co2+ 209909 2.7.7.53 Mn2+ not NDP-arsenolysis or NDP/phosphate-exchange reaction 643510 2.7.7.53 Mn2+ required 643507 2.7.7.53 Mn2+ requirement, Ap4A-synthesis 643508 2.7.7.53 Mn2+ Rv2613c requires bivalent metal ions such as Mn2+ to exert its Ap4A phosphorylase activity (100% activity in the presence of 2 mM Mn2+) 713455 2.7.7.53 additional information Cu2+ 643508 2.7.7.53 additional information no activation by Ni2+ 643507, 643508 2.7.7.53 additional information no divalent metal cation requirement for NDP-arsenolysis or NDP/phosphate-exchange reaction 643510, 643513 2.7.7.53 Zn2+ no effect 643507 2.7.7.53 Zn2+ slight activation 209909, 643515 2.7.7.53 Zn2+ slight activation of P1,P4-bis(5'-adenosyl) tetraphosphate-synthesis 643508