1.2.1.3 Ba2+ the activity is elevated to 2-3fold in the presence of 2 mM Ba2+ 697840 1.2.1.3 BaCl2 0.1 mM, slight activation of microsomal enzyme 348706 1.2.1.3 Ca2+ 150% activity at 1 mM 712957 1.2.1.3 Ca2+ the activity is elevated to 2-3fold in the presence of 2 mM Ca2+ 697840 1.2.1.3 CaCl2 0.1 mM, slight activation of microsomal enzyme 348706 1.2.1.3 CsCl 0.1 mM, slight activation of microsomal enzyme 348706 1.2.1.3 Fe2+ required 719938, 729577 1.2.1.3 Iron enzyme contains 2 iron-sulfur centres 348684 1.2.1.3 K+ 118% activity at 1 mM 712957 1.2.1.3 K+ 130% activity at 20 mM 722210 1.2.1.3 K+ activation seems to be due to increase of ionic strength 348725 1.2.1.3 K+ K+-activated enzyme 348724 1.2.1.3 K+ slight activation 348681, 348725 1.2.1.3 Li+ 119% activity at 20 mM 722210 1.2.1.3 Mg2+ - 672038, 675118 1.2.1.3 Mg2+ 0.5 mM, slight activation 348791 1.2.1.3 Mg2+ 180% activity at 1 mM 712957 1.2.1.3 Mg2+ 23% activation at 1 mM 671542 1.2.1.3 Mg2+ activates 348686 1.2.1.3 Mg2+ activation of isoenzyme I and II 348705 1.2.1.3 Mg2+ Mg2+ ions stimulate the enantioselective oxidation of (R)-trans-4-hydroxy-2-nonenal by ALDH2 while suppressing (S)-trans-4-hydroxy-2-nonenal oxidation 691775 1.2.1.3 Mg2+ no effect 348706 1.2.1.3 Mn2+ 140% activity at 1 mM 712957 1.2.1.3 Molybdenum enzyme contains a molybdopterin binding domain 348684 1.2.1.3 additional information 1 mM Na+ has no effect on the enzyme activity 712957 1.2.1.3 additional information enzyme does not contain significant amounts of metal ion 348712 1.2.1.3 additional information the enzyme is not influenced by 20 mM Mg2, Cu2+, Ca2+, Ba2+, Ni2+, Co2+, and Sr2+ 722210 1.2.1.3 Na+ 122% activity at 20 mM 722210 1.2.1.3 NaCl 0.1 mM, slight activation of microsomal enzyme 348706 1.2.1.3 NH4+ 13% activation at 1 mM 671542 1.2.1.3 NH4+ 131% activity at 20 mM 722210 1.2.1.3 NiCl2 0.1 mM, slight activation of microsomal enzyme 348706 1.2.1.3 Sr2+ the activity is elevated to 2-3fold in the presence of 2 mM Sr2+ 697840