1.1.1.145 3beta-hydroxy-DELTA5-steroid dehydrogenase mitochondrial inner membrane - 5743 724302, 725511 1.1.1.211 long-chain-3-hydroxyacyl-CoA dehydrogenase mitochondrial inner membrane - 5743 286269 1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+) mitochondrial inner membrane - 5743 667798 1.1.2.4 D-lactate dehydrogenase (cytochrome) mitochondrial inner membrane the enzyme is located on the inner face of the inner mitochondrial membrane 5743 740447 1.1.5.3 glycerol-3-phosphate dehydrogenase mitochondrial inner membrane - 5743 -, 723350 1.1.5.3 glycerol-3-phosphate dehydrogenase mitochondrial inner membrane the active site of mGPDH faces the mitochondrial intermembrane space, as does its calcium-sensitive EF-hand domain 5743 -, 741302 1.1.99.1 choline dehydrogenase mitochondrial inner membrane a nuclear-encoded, membrane-located, mitochondrial enzyme 5743 741756 1.1.99.1 choline dehydrogenase mitochondrial inner membrane a nuclear-encoded, membrane-located, mitochondrial enzyme. Human CHD is not an integral membrane protein, but associated to the membrane 5743 741756 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase mitochondrial inner membrane - 5743 -, 764207 1.13.11.71 carotenoid-9',10'-cleaving dioxygenase mitochondrial inner membrane - 5743 745596 1.14.14.1 unspecific monooxygenase mitochondrial inner membrane CYP24A1 and CYP27A1 5743 701574 1.14.15.4 steroid 11beta-monooxygenase mitochondrial inner membrane - 5743 726012 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) mitochondrial inner membrane - 5743 -, 285415, 285416, 285417, 285419, 285422, 285423, 285424, 285425, 285427, 285428, 285431, 285432, 703100, 712924, 725962 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) mitochondrial inner membrane adrenodoxin reductase and adrenodoxin are peripheral proteins on matrix side of inner membrane, P-450scc is integral membrane protein 5743 285413, 285414 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) mitochondrial inner membrane electron carriers and P-450 liquid-bound within mitochondrion 5743 285418 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) mitochondrial inner membrane inner membrane 5743 285426, 285429, 285430, 285433 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) mitochondrial inner membrane integral to membrane 5743 285412, 285414, 285421 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) mitochondrial inner membrane matrix side 5743 285420, 285429 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) mitochondrial inner membrane membrane topology, overview 5743 673298 1.17.99.9 heme a synthase mitochondrial inner membrane Cox15p is a constituent of the mitochondrial inner membrane 5743 759454 1.2.1.105 2-oxoglutarate dehydrogenase system mitochondrial inner membrane enzyme E2 overexpression or disruption of mitochondrial membrane potential causes enzyme E2 release from mitochondria to cytoplasm where it is degraded 5743 656265 1.2.1.25 branched-chain alpha-keto acid dehydrogenase system mitochondrial inner membrane human BCKD complex is likely located on the matrix side of the inner mitochondrial membrane 5743 762596 1.2.1.36 retinal dehydrogenase mitochondrial inner membrane outer side 5743 686690 1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring) mitochondrial inner membrane - 5743 656596 1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring) mitochondrial inner membrane associated with 5743 654699 1.3.2.3 L-galactonolactone dehydrogenase mitochondrial inner membrane GLDH behaves as an integral protein of the inner membrane facing the intermembrane space 5743 -, 746093 1.3.3.4 protoporphyrinogen oxidase mitochondrial inner membrane - 5743 654874 1.3.3.4 protoporphyrinogen oxidase mitochondrial inner membrane analysis of mitochondrial targeting sequences of wild-type and mutant enzymes, overview 5743 655497 1.3.5.1 succinate dehydrogenase mitochondrial inner membrane - 5743 -, 686649, 712018, 713193, 763269 1.3.5.1 succinate dehydrogenase mitochondrial inner membrane the catalytic domain (SDH1 and 2) is extrinsic on the matrix side, while the anchor subunits (SDH3 and 4) are intrinsic transmembrane proteins, allowing transfer of the electrons from succinate in the mitochondrial matrix to ubiquinone in the inner membrane 5743 762895 1.3.5.1 succinate dehydrogenase mitochondrial inner membrane the catalytic domain (SDHA and B) is extrinsic on the matrix side, while the anchor subunits (SDHC and D) are intrinsic transmembrane proteins, allowing transfer of the electrons from succinate in the mitochondrial matrix to ubiquinone in the inner membrane 5743 762895 1.3.5.1 succinate dehydrogenase mitochondrial inner membrane the membrane domain consists of two subunits SdhC and SdhD. The membrane domain contains a bound heme b moiety at the subunit interface with SdhC and SdhD each providing one of the two axial His ligands 5743 712976 1.3.5.2 dihydroorotate dehydrogenase (quinone) mitochondrial inner membrane - 5743 712071 1.3.8.6 glutaryl-CoA dehydrogenase (ETF) mitochondrial inner membrane - 5743 712280 1.3.99.32 glutaryl-CoA dehydrogenase (acceptor) mitochondrial inner membrane - 5743 712280 1.5.1.2 pyrroline-5-carboxylate reductase mitochondrial inner membrane - 5743 672935, 674605, 676262 1.5.5.1 electron-transferring-flavoprotein dehydrogenase mitochondrial inner membrane - 5743 726447 1.5.5.1 electron-transferring-flavoprotein dehydrogenase mitochondrial inner membrane bound to via ubiquinone binding domain, overview 5743 724410 1.5.5.2 proline dehydrogenase mitochondrial inner membrane co-localization with the electron transport chain on the inner membrane of the mitochondria 5743 741588 1.5.5.2 proline dehydrogenase mitochondrial inner membrane TcPRODH is associated with the mitochondrial inner membrane, identification of a predicted N-terminal mitochondrial targeting signal, followed by a putative transmembrane alpha helix spanning domain 5743 -, 743635 1.5.99.B2 proline dehydrogenase (acceptor) mitochondrial inner membrane - 5743 699706, 742204 1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific) mitochondrial inner membrane - 5743 -, 658473, 696513, 724435, 725068, 725514 1.6.1.3 NAD(P)+ transhydrogenase mitochondrial inner membrane - 5743 724928 1.8.5.8 eukaryotic sulfide quinone oxidoreductase mitochondrial inner membrane membrane-anchored 5743 764977 1.8.5.8 eukaryotic sulfide quinone oxidoreductase mitochondrial inner membrane mitochondrial inner membrane-anchored enzyme 5743 764484 2.1.1.41 sterol 24-C-methyltransferase mitochondrial inner membrane some activity 5743 485327, 485328 2.1.2.10 aminomethyltransferase mitochondrial inner membrane - 5743 391993, 706478 2.1.4.1 glycine amidinotransferase mitochondrial inner membrane - 5743 485975 2.3.1.12 dihydrolipoyllysine-residue acetyltransferase mitochondrial inner membrane pyruvate dehydrogenase complex bound to inner mitochondrial membrane 5743 348927 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase mitochondrial inner membrane - 5743 486362, 486372 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase mitochondrial inner membrane cytoplasmic side of inner membrane 5743 486381 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase mitochondrial inner membrane significant acyltransferase activity in inner membrane 5743 486377 2.3.1.21 carnitine O-palmitoyltransferase mitochondrial inner membrane - 5743 486541, 486544, 703967, 705753 2.3.1.21 carnitine O-palmitoyltransferase mitochondrial inner membrane CPT2 5743 659899 2.3.1.21 carnitine O-palmitoyltransferase mitochondrial inner membrane enzyme from outer and from inner membrane have different properties 5743 486535, 486536 2.3.1.21 carnitine O-palmitoyltransferase mitochondrial inner membrane enzyme is present on both sides of the inner membrane, not on the outer membrane 5743 486537, 486557 2.3.1.21 carnitine O-palmitoyltransferase mitochondrial inner membrane inner face of inner membrane 5743 486552, 486553, 486555, 486558, 486561, 486566 2.3.1.21 carnitine O-palmitoyltransferase mitochondrial inner membrane outer face of inner membrane 5743 486523, 486538, 486553, 486555, 486556 2.3.1.37 5-aminolevulinate synthase mitochondrial inner membrane loosely bound 5743 486818 2.3.1.B43 protein-lysine desuccinylase (NAD+) mitochondrial inner membrane SIRT5 is targeted to protein complexes on the inner mitochondrial membrane via affinity for cardiolipin 5743 757175 2.3.3.16 citrate synthase (unknown stereospecificity) mitochondrial inner membrane 45% of CS II is bound to mitochondrial inner membrane and 2% of CS I 5743 488068 2.5.1.39 4-hydroxybenzoate polyprenyltransferase mitochondrial inner membrane - 5743 636998 2.6.1.7 kynurenine-oxoglutarate transaminase mitochondrial inner membrane - 5743 -, 636623 2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase mitochondrial inner membrane - 5743 642137 2.7.3.2 creatine kinase mitochondrial inner membrane - 5743 737427 2.7.4.6 nucleoside-diphosphate kinase mitochondrial inner membrane NDPK is attached to the outer side of the inner the membrane 5743 672407 2.7.4.6 nucleoside-diphosphate kinase mitochondrial inner membrane structural basis of NDPK-D/mitochondrial membrane interactions via binding of cardiolipin, overview 5743 693134 2.7.4.6 nucleoside-diphosphate kinase mitochondrial inner membrane structural basis of NDPK-D/mitochondrial membrane interactions, overview 5743 693134 2.7.7.41 phosphatidate cytidylyltransferase mitochondrial inner membrane - 5743 738000 2.8.2.B1 APS sulfotransferase mitochondrial inner membrane periplasmic side 5743 289091 3.1.3.43 [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase mitochondrial inner membrane inner surface of the inner membrane 5743 94914 3.4.21.105 rhomboid protease mitochondrial inner membrane - 5743 659997 3.4.21.89 Signal peptidase I mitochondrial inner membrane - 5743 29808, 29815 3.4.24.B18 m-AAA protease mitochondrial inner membrane - 5743 653198, 681927, 711611, 712130, 712541, 712981, 713349, 718997 3.4.24.B18 m-AAA protease mitochondrial inner membrane both subunit types span the membrane twice, integral, active at the matrix side of the inner membrane 5743 649814 3.4.24.B18 m-AAA protease mitochondrial inner membrane inner side, exposes catalytic sites to the mitochondrial matrix 5743 650958 3.4.24.B18 m-AAA protease mitochondrial inner membrane integral, active at the matrix side of the inner membrane 5743 649814, 650372 3.4.24.B19 i-AAA protease mitochondrial inner membrane - 5743 653183, 681916, 692511, 694091 3.4.24.B19 i-AAA protease mitochondrial inner membrane integral, a large domain is exposed to the intermembrane space 5743 650958 3.4.24.B19 i-AAA protease mitochondrial inner membrane integral, catalytic site facing the intermembrane space 5743 649814 3.4.24.B19 i-AAA protease mitochondrial inner membrane only subunit type Yme1p spans the membrane once, integral, catalytic site facing the inter membrane space 5743 649814 3.4.24.B19 i-AAA protease mitochondrial inner membrane outer surface of 5743 653335 3.4.99.B2 D-aspartyl endopeptidase mitochondrial inner membrane - 5743 667380, 695517 3.6.4.10 non-chaperonin molecular chaperone ATPase mitochondrial inner membrane associated to on the matrix side 5743 734351 3.6.5.5 dynamin GTPase mitochondrial inner membrane - 5743 689227 3.6.5.5 dynamin GTPase mitochondrial inner membrane Drp1 assembles into large complexes at future scission sites on the inner mitochondrial membrane 5743 686382 4.1.1.65 phosphatidylserine decarboxylase mitochondrial inner membrane - 5743 4765, 4771, 4782, 4783, 4788 4.1.1.65 phosphatidylserine decarboxylase mitochondrial inner membrane exclusively in the inner mitochondrial membrane 5743 4779, 4791 4.1.1.65 phosphatidylserine decarboxylase mitochondrial inner membrane external side of the inner membrane 5743 4777 4.1.1.65 phosphatidylserine decarboxylase mitochondrial inner membrane inner membrane 5743 4776, 4783 4.1.1.65 phosphatidylserine decarboxylase mitochondrial inner membrane membrane 5743 4761, 4776 4.1.2.27 sphinganine-1-phosphate aldolase mitochondrial inner membrane inner mitochondrial membrane possesses the highest activity 5743 5112 4.1.2.27 sphinganine-1-phosphate aldolase mitochondrial inner membrane membrane-bound 5743 5112 4.2.1.17 enoyl-CoA hydratase mitochondrial inner membrane - 5743 714222 4.4.1.17 Holocytochrome-c synthase mitochondrial inner membrane - 5743 94056, 94057, 94058 4.4.1.17 Holocytochrome-c synthase mitochondrial inner membrane integral membrane protein, facing cytoplasmic surface 5743 94055 4.4.1.17 Holocytochrome-c synthase mitochondrial inner membrane separation of mitochondrial inner and outer membrane on a sucrose gradient 5743 665678 4.98.1.1 protoporphyrin ferrochelatase mitochondrial inner membrane - 5743 729221, 729863 5.6.2.3 DNA 5'-3' helicase mitochondrial inner membrane - 5743 757877 6.3.2.17 tetrahydrofolate synthase mitochondrial inner membrane the mitochondrial isoform is an integral membrane protein 5743 744775