2.7.11.16 cell membrane association of GRK6 with the cell membrane is mediated in part by the palmitoylation of cysteine residues that lie in a C-terminal region - 674574 2.7.11.16 centrosome GRK5 co-localizes with gamma-tubulin, centrin, and pericentrin in centrosomes. The centrosomal localization of GRK5 is observed predominantly at interphase and although its localization is not dependent on microtubules, it can mediate microtubule nucleation of centrosome 5813 725509 2.7.11.16 cytoplasm - 5737 671352, 726308 2.7.11.16 cytoplasm the GRK5 subcellular distribution in the human striatal neurons is altered by its phosphorylation: phosphorylated GRK5 is found in plasma membrane and cytosolic fractions 5737 726308 2.7.11.16 cytosol - 5829 661667 2.7.11.16 membrane - 16020 661667, 672408, 685121 2.7.11.16 membrane anchoring of GRK4 by palmitoyl residue at the C-terminus 16020 662921 2.7.11.16 membrane anchoring via palmitoylation 16020 662767 2.7.11.16 membrane cytosolic side of the plasma membrane 16020 762419 2.7.11.16 membrane GRK5 protein does not undergo agonist-dependent translocation from cytosol to membranes as do beta-adrenergic receptor kinase and rhodopsin kinase, but rather appears to associate with membranes constitutively 16020 491154