1.1.1.10 L-xylulose reductase intracellular - 5622 -, 760730 1.1.1.145 3beta-hydroxy-DELTA5-steroid dehydrogenase intracellular - 5622 685186 1.1.1.17 mannitol-1-phosphate 5-dehydrogenase intracellular - 5622 -, 285902, 285907, 389412, 389413, 389415, 389418, 389419, 389421, 389423, 389424, 389426 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+) intracellular - 5622 -, 286228 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+) intracellular - 5622 -, 672761 1.1.1.93 tartrate dehydrogenase intracellular - 5622 389613 1.1.3.10 pyranose oxidase intracellular - 5622 656544 1.1.3.18 secondary-alcohol oxidase intracellular - 5622 -, 348180 1.1.3.4 glucose oxidase intracellular - 5622 389792, 672763 1.1.3.4 glucose oxidase intracellular isozyme 1 5622 -, 676974 1.1.3.6 cholesterol oxidase intracellular - 5622 -, 688918, 697915, 742970 1.1.3.6 cholesterol oxidase intracellular the lack of a signal peptide indicated the intracellular localization of the enzyme in the native host 5622 -, 742195 1.1.3.9 galactose oxidase intracellular - 5622 389862 1.1.3.9 galactose oxidase intracellular intracellular enzyme possesses a more restricted substrate specificity than the extracellular form 5622 389858 1.1.99.29 pyranose dehydrogenase (acceptor) intracellular - 5622 -, 644546 1.10.3.2 laccase intracellular - 5622 396341, 396372 1.10.3.6 rifamycin-B oxidase intracellular - 5622 439884 1.11.1.21 catalase-peroxidase intracellular - 5622 -, 696108, 765406 1.11.1.6 catalase intracellular - 5622 654036, 687862 1.11.1.6 catalase intracellular catalase-peroxidase enzyme 5622 -, 439784 1.11.1.6 catalase intracellular mainly 5622 -, 654036 1.11.1.7 peroxidase intracellular - 5622 -, 439741, 663928 1.11.1.9 glutathione peroxidase intracellular - 5622 658820 1.13.11.1 catechol 1,2-dioxygenase intracellular - 5622 -, 676763 1.13.11.31 arachidonate 12-lipoxygenase intracellular - 5622 765361 1.13.11.52 indoleamine 2,3-dioxygenase intracellular - 5622 687056 1.13.12.7 firefly luciferase intracellular - 5622 484825, 701048 1.14.11.4 procollagen-lysine 5-dioxygenase intracellular - 5622 675766 1.14.13.7 phenol 2-monooxygenase (NADPH) intracellular - 5622 658569 1.14.14.20 phenol 2-monooxygenase (FADH2) intracellular - 5622 -, 736171 1.15.1.1 superoxide dismutase intracellular - 5622 728279 1.15.1.1 superoxide dismutase intracellular highest activity in early log phase culture 5622 673379 1.17.3.2 xanthine oxidase intracellular - 5622 -, 715069 1.17.4.1 ribonucleoside-diphosphate reductase intracellular almost entirely 5622 437960 1.2.1.92 3,6-anhydro-alpha-L-galactose dehydrogenase intracellular VvAHGD lacks an N-terminal signal peptide sequence based on SignalP 4.1 prediction, consistent with its intracellular location 5622 -, 763364 1.21.3.4 sulochrin oxidase [(+)-bisdechlorogeodin-forming] intracellular no extracellular activity 5622 -, 437825 1.21.3.5 sulochrin oxidase [(-)-bisdechlorogeodin-forming] intracellular no extracellular activity 5622 437825 1.21.99.1 beta-cyclopiazonate dehydrogenase intracellular - 5622 394676 1.4.1.1 alanine dehydrogenase intracellular - 5622 349594 1.4.1.20 phenylalanine dehydrogenase intracellular - 5622 -, 349642 1.4.3.25 L-arginine oxidase intracellular small part of the protein 5622 -, 740093 1.5.8.1 dimethylamine dehydrogenase intracellular - 5622 -, 393884 1.5.8.2 trimethylamine dehydrogenase intracellular - 5622 -, 393884 1.6.5.2 NAD(P)H dehydrogenase (quinone) intracellular - 5622 394360, 394370 1.7.1.6 azobenzene reductase intracellular - 5622 -, 394295, 741799 1.7.3.3 factor-independent urate hydroxylase intracellular - 5622 -, 394150, 658371, 659535 1.7.3.3 factor-independent urate hydroxylase intracellular isoform UIV 5622 724149 1.8.3.2 thiol oxidase intracellular both intra- and extracellular 5622 -, 723985 1.8.3.3 glutathione oxidase intracellular - 5622 -, 394886 1.8.4.12 peptide-methionine (R)-S-oxide reductase intracellular - 5622 668357 2.1.1.28 phenylethanolamine N-methyltransferase intracellular - 5622 -, 697358 2.1.2.10 aminomethyltransferase intracellular - 5622 705607 2.3.1.304 poly[(R)-3-hydroxyalkanoate] polymerase intracellular - 5622 755878 2.3.1.45 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase intracellular - 5622 487038 2.3.1.B41 protein-long-chain fatty-acyl-lysine deacylase (NAD+) intracellular - 5622 756689 2.3.2.13 protein-glutamine gamma-glutamyltransferase intracellular - 5622 759712 2.3.2.13 protein-glutamine gamma-glutamyltransferase intracellular intracellular TG1 activity is unlikely to contribute extracellularly to extracellular matrix crosslinking 5622 759166 2.4.1.10 levansucrase intracellular - 5622 -, 488324, 735800, 735894, 736891 2.4.1.10 levansucrase intracellular recombinant enzyme expressed in Escherichia coli 5622 -, 488326 2.4.1.16 chitin synthase intracellular - 5622 736241 2.4.1.16 chitin synthase intracellular membrane-bound vesicle, Chs3p is present in an active form 5622 658577 2.4.1.183 alpha-1,3-glucan synthase intracellular - 5622 -, 759245 2.4.1.19 cyclomaltodextrin glucanotransferase intracellular - 5622 -, 488824, 488855 2.4.1.2 dextrin dextranase intracellular cell surface, the cell-associated form (DDint) appears after depletion of glucose from the medium 5622 -, 735605 2.4.1.2 dextrin dextranase intracellular cytoplasmic 5622 659632 2.4.1.211 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase intracellular - 5622 288692 2.4.1.236 flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase intracellular - 5622 488818 2.4.1.319 beta-1,4-mannooligosaccharide phosphorylase intracellular - 5622 -, 725502 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase intracellular CHO ldlD-MUC1 cells in presence of GalNAc 5622 686971 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase intracellular CHO ldlD-MUC1 cells in presence of GalNAc: same pattern of biotinylated GalNAc-T2 like Tn (GalNAc-alpha-Ser/Thr) 5622 686971 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase intracellular CHO ldlD-MUC1 cells in presence of GalNAc: same pattern of biotinylated GalNAc-T4 and -T4 lectin like Tn (GalNAc-alpha-Ser/Thr) 5622 686971 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase intracellular human salivary glands 5622 686971 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase intracellular human salivary glands: same pattern of biotinylated GalNAc-T2 at Golgi-like supranuclear locations like Tn (GalNAc-alpha-Ser/Thr) 5622 686971 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase intracellular human salivary glands: same pattern of biotinylated GalNAc-T4 lectin at Golgi-like supranuclear locations like Tn (GalNAc-alpha-Ser/Thr) 5622 686971 2.4.1.5 dextransucrase intracellular - 5622 -, 720161 2.4.1.66 procollagen glucosyltransferase intracellular - 5622 636781 2.4.1.66 procollagen glucosyltransferase intracellular kidney enzyme 5622 675031 2.4.1.7 sucrose phosphorylase intracellular - 5622 -, 736139 2.4.1.90 N-acetyllactosamine synthase intracellular estrogen-induced expression of B4GALT1 is localized in intracellular compartments and in the plasma membrane 5622 718763 2.7.1.136 macrolide 2'-kinase intracellular - 5622 640839 2.7.1.158 inositol-pentakisphosphate 2-kinase intracellular spatial microheterogeneity in the intracellular localization of IP5K in NRK cells, COS7 cell and H1299 overexpressing EGFP-IP5K fusion proteins, also confirmed for the endogenous enzyme 5622 671904 2.7.1.171 protein-fructosamine 3-kinase intracellular - 5622 760800 2.7.1.189 autoinducer-2 kinase intracellular - 5622 734624, 752175 2.7.1.B20 broad specificity nucleoside kinase intracellular - 5622 728780 2.7.10.2 non-specific protein-tyrosine kinase intracellular - 5622 490444 2.7.11.13 protein kinase C intracellular intracellular localization pattern during cyst formation 5622 671653 2.7.11.13 protein kinase C intracellular localization of PKC isozymes alpha, delta, and gamma, is influenced by hypericin, high affinity binding and interaction with the C1B domain of PKC, molecular modeling 5622 676323 2.7.4.3 adenylate kinase intracellular extracellular activity is less than 1% of total activity and due to leaking from leaving cells or to dying cells 5622 674609 2.8.2.23 [heparan sulfate]-glucosamine 3-sulfotransferase 1 intracellular - 5622 762294 2.8.2.30 [heparan sulfate]-glucosamine 3-sulfotransferase 3 intracellular - 5622 762294 3.1.1.1 carboxylesterase intracellular - 5622 -, 724578, 728068, 749674 3.1.1.1 carboxylesterase intracellular the AT domain contains an N-terminal signal sequence that targets the enzyme to the Sec machinery in the inner membrane 5622 -, 752220 3.1.1.118 phospholipid sn-1 acylhydrolase intracellular - 5622 762106 3.1.1.13 sterol esterase intracellular - 5622 133845 3.1.1.20 tannase intracellular - 5622 -, 678756, 750838 3.1.1.20 tannase intracellular 5fold higher production level in culture than the extracellular form 5622 -, 651738 3.1.1.20 tannase intracellular intracellular tannase is tightly bound with the mycelium 5622 680530 3.1.1.22 hydroxybutyrate-dimer hydrolase intracellular - 5622 -, 650922, 652588, 664692, 750947, 751154 3.1.1.3 triacylglycerol lipase intracellular - 5622 -, 650654, 666381, 714773 3.1.1.3 triacylglycerol lipase intracellular second enzyme form 5622 -, 665891 3.1.1.3 triacylglycerol lipase intracellular second, minor enzyme form 5622 -, 664236 3.1.1.32 phospholipase A1 intracellular - 5622 -, 681568, 716165, 730037 3.1.1.39 actinomycin lactonase intracellular - 5622 80928 3.1.1.4 phospholipase A2 intracellular isozymes GIVA cPLA2 and GVIA iPLA2 5622 691210 3.1.1.42 chlorogenate hydrolase intracellular - 5622 651606 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase intracellular - 5622 651794, 652697, 653707, 669511, 681267, 714085, 715638 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase intracellular 4 isozymes, i.e. isozyme Ia, Ib, II, and the erythrocyte form, physiological functions, overview 5622 650326 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase intracellular isozymes Ib and II 5622 653695 3.1.1.53 sialate O-acetylesterase intracellular - 5622 730718 3.1.1.55 acetylsalicylate deacetylase intracellular - 5622 715638 3.1.1.75 poly(3-hydroxybutyrate) depolymerase intracellular - 5622 -, 208347, 663789, 664692, 664693, 680471, 680988, 702902, 728941, 729044, 750947, 751154 3.1.1.75 poly(3-hydroxybutyrate) depolymerase intracellular associated with poly(3-hydroxybutyrate) granules 5622 665369 3.1.1.75 poly(3-hydroxybutyrate) depolymerase intracellular partially at poly(3-hydroxybutyrate) bodies and in the cytosol 5622 -, 665392 3.1.1.76 poly(3-hydroxyoctanoate) depolymerase intracellular - 5622 -, 680871 3.1.1.B12 zearalenone hydrolase intracellular - 5622 -, 762862 3.1.2.22 palmitoyl[protein] hydrolase intracellular the most common mutation results in intracellular accumulation of the enzyme polypeptide and undetectable activity in the brain 5622 23912 3.1.26.12 ribonuclease E intracellular - 5622 -, 750962 3.1.26.12 ribonuclease E intracellular RNaseE is organized as a cytoskeletal structure in vivo. RNaseE and the other known degradosome components (RNA helicase B, polynucleotide phosphorylase, and enolase) are organized as helical filamentous structures that coil around the length of the cell. These resemble the helical structures formed by the MreB and MinD cytoskeletal proteins. Formation of the RNaseE cytoskeletal-like structure requires an internal domain of the protein that does not include the domains required for any of its known interactions or the minimal domain required for endonuclease activity. The constituents of the RNA degradosome are components of the Escherichia coli cytoskeleton, either assembled as a primary cytoskeletal structure or secondarily associated with another underlying cytoskeletal element 5622 -, 752028 3.1.3.1 alkaline phosphatase intracellular - 5622 680124, 692420 3.1.3.1 alkaline phosphatase intracellular mycelial enzyme form 5622 652689 3.1.3.10 glucose-1-phosphatase intracellular - 5622 -, 715067 3.1.3.16 protein-serine/threonine phosphatase intracellular - 5622 752314 3.1.3.2 acid phosphatase intracellular - 5622 651405, 663928, 664392, 730275 3.1.3.2 acid phosphatase intracellular isozyme 5a 5622 665956 3.1.3.26 4-phytase intracellular - 5622 -, 650693 3.1.3.26 4-phytase intracellular recombinant enzyme expressed in Escherichia coli 5622 -, 650754 3.1.3.48 protein-tyrosine-phosphatase intracellular - 5622 750465, 95012 3.1.3.5 5'-nucleotidase intracellular - 5622 716355 3.1.3.51 dolichyl-phosphatase intracellular perikaryon 5622 134909 3.1.3.64 phosphatidylinositol-3-phosphatase intracellular - 5622 715016 3.1.3.8 3-phytase intracellular - 5622 -, 114279, 650693, 715777 3.1.3.8 3-phytase intracellular among 10 yeast strains analyzed, Arxula adeninivorans and Pichia anomala display highest volumetric phytase activities and Arxula adeninivorans shows the highest intra- and extracellular specific activities 5622 708526 3.1.3.8 3-phytase intracellular recombinant enzyme expressed in Escherichia coli 5622 -, 650754 3.1.30.1 Aspergillus nuclease S1 intracellular - 5622 134997 3.1.4.12 sphingomyelin phosphodiesterase intracellular the ratio of secreted to intracellular activity is about 8fold greater in I-cells (skin fibroblasts from I-cell disease patients, in which one of the enzymes responsible for mannose phosphorylation, GlcNAc-phosphotransferase, is deficient) than in normal cells 5622 666964 3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase intracellular perikaryon 5622 135420 3.1.4.4 phospholipase D intracellular isozyme PLD1 is found throughout the cell, but primarily localizes to intracellular compartments, including the Golgi apparatus, endosomes, and the perinuclear region 5622 730316 3.1.4.4 phospholipase D intracellular phosphorylation of cofilin on Ser3 by LIM-kinase 1 correlates with a relocalisation of PLD1 from a predominantly intracellular localisation to the plasma membrane 5622 707550 3.1.6.1 arylsulfatase (type I) intracellular 32% of arylsulfatase acivity is intracellular 5622 -, 730337 3.2.1.1 alpha-amylase intracellular - 5622 -, 393426, 393429, 393447, 663719, 701883, 752105 3.2.1.1 alpha-amylase intracellular alpha-amylase is primarily extracellular 5622 721313 3.2.1.1 alpha-amylase intracellular AmyD 5622 681802 3.2.1.1 alpha-amylase intracellular contains cell-associated and secreted alpha-amylase. Inactivation of the amyA gene results in a complete loss of activity, suggesting that the same protein is responsible for the alpha-amylase activity at both locations 5622 -, 724931 3.2.1.1 alpha-amylase intracellular recombinant protein in Xanthomonas campestris, a Gram-negative bacterium 5622 690492 3.2.1.10 oligo-1,6-glucosidase intracellular - 5622 -, 725283 3.2.1.10 oligo-1,6-glucosidase intracellular no predicted signal peptide is observed, suggesting an intracellular localization for the enzyme 5622 -, 750849 3.2.1.11 dextranase intracellular - 5622 135735, 135741 3.2.1.11 dextranase intracellular dextranase D4 5622 -, 666256 3.2.1.113 mannosyl-oligosaccharide 1,2-alpha-mannosidase intracellular with strain 22A1, the ratio of intracellular to extracellular 1,2-alpha-mannosidase activity is about 4:1 5622 664385 3.2.1.114 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase intracellular SpGH38 may be intracellular, absence of any classical signal peptide 5622 710392 3.2.1.123 endoglycosylceramidase intracellular - 5622 646688 3.2.1.131 xylan alpha-1,2-glucuronosidase intracellular - 5622 -, 732768 3.2.1.132 chitosanase intracellular - 5622 708001 3.2.1.133 glucan 1,4-alpha-maltohydrolase intracellular - 5622 -, 646799, 664997, 727388 3.2.1.133 glucan 1,4-alpha-maltohydrolase intracellular recombinant enzyme MAUS149 5622 -, 681861 3.2.1.135 neopullulanase intracellular - 5622 664673 3.2.1.135 neopullulanase intracellular isozyme TVAII 5622 -, 664673 3.2.1.139 alpha-glucuronidase intracellular - 5622 -, 26100, 26103, 664345 3.2.1.14 chitinase intracellular - 5622 717732 3.2.1.147 thioglucosidase intracellular - 5622 -, 208564, 208567 3.2.1.156 oligosaccharide reducing-end xylanase intracellular - 5622 -, 659431 3.2.1.157 iota-carrageenase intracellular - 5622 -, 754224 3.2.1.158 alpha-agarase intracellular - 5622 -, 705484 3.2.1.166 heparanase intracellular heparanase is the only known mammalian endoglycosidase capable of degrading heparan sulfate glycosaminoglycan, both in extracellular space and within the cells 5622 732436 3.2.1.2 beta-amylase intracellular - 5622 -, 208609, 727388 3.2.1.20 alpha-glucosidase intracellular - 5622 -, 393264, 393276, 393279, 393283, 393286, 393292, 393345, 393349, 655050, 656703, 663905, 694053, 725283, 729647, 748424 3.2.1.20 alpha-glucosidase intracellular primarily an intracellular enzyme 5622 721313 3.2.1.21 beta-glucosidase intracellular - 5622 -, 326278, 326288, 326294, 326304, 326314, 326326, 326339, 326346, 326352, 326355, 326358, 326367, 654224, 663799, 664149, 664415, 665789, 666820, 666845, 742180, 744194 3.2.1.21 beta-glucosidase intracellular beta-glucosidase IV 5622 326324 3.2.1.21 beta-glucosidase intracellular expression of mRNA higher with cellobiose than with glucose as a carbon source 5622 326306 3.2.1.21 beta-glucosidase intracellular induction of enzyme synthesis by addition of cellobiose or laminaribiose to the medium 5622 326325 3.2.1.21 beta-glucosidase intracellular present in the very early growth phase 5622 326303 3.2.1.21 beta-glucosidase intracellular stimulation of enzyme synthesis by cellobiose as carbohydrate source 5622 326283, 326295 3.2.1.216 kojibiose hydrolase intracellular - 5622 -, 725283 3.2.1.22 alpha-galactosidase intracellular - 5622 -, 655085, 698429 3.2.1.23 beta-galactosidase intracellular - 5622 -, 171289, 171308, 171332, 171344, 171352, 657240, 665287, 679560, 681772 3.2.1.23 beta-galactosidase intracellular 12-16% of the activity 5622 171314 3.2.1.23 beta-galactosidase intracellular GH42 enzyme LacA 5622 677681 3.2.1.24 alpha-mannosidase intracellular SpGH38 may be intracellular, absence of any classical signal peptide 5622 710392 3.2.1.25 beta-mannosidase intracellular - 5622 -, 654244, 656701 3.2.1.26 beta-fructofuranosidase intracellular - 5622 -, 136071, 136081, 136103, 136125, 136133, 654834, 655084, 656676, 750987 3.2.1.26 beta-fructofuranosidase intracellular 90% of total enzyme amount 5622 666543 3.2.1.26 beta-fructofuranosidase intracellular extracellular and intracellular enzyme 5622 136132 3.2.1.28 alpha,alpha-trehalase intracellular - 5622 136179, 741947, 741949 3.2.1.28 alpha,alpha-trehalase intracellular intracellular and extracellular enzyme 5622 136164 3.2.1.28 alpha,alpha-trehalase intracellular neutral trehalase 5622 -, 664188 3.2.1.28 alpha,alpha-trehalase intracellular the internal trehalase can be separated into a cell wall-bound and a soluble intracellular fraction 5622 -, 136170 3.2.1.3 glucan 1,4-alpha-glucosidase intracellular - 5622 679524 3.2.1.31 beta-glucuronidase intracellular recombinant enzyme in BHK cells 5622 654474 3.2.1.35 hyaluronoglucosaminidase intracellular - 5622 690383 3.2.1.35 hyaluronoglucosaminidase intracellular venom gland enzyme 5622 665038 3.2.1.37 xylan 1,4-beta-xylosidase intracellular - 5622 136282, 136284, 136286, 136303, 136314, 655008, 683995, 750810 3.2.1.39 glucan endo-1,3-beta-D-glucosidase intracellular - 5622 136338, 136346, 136364, 136378 3.2.1.39 glucan endo-1,3-beta-D-glucosidase intracellular beta-glucanases I, IIIB and V 5622 136362 3.2.1.40 alpha-L-rhamnosidase intracellular - 5622 -, 654992, 679562, 750590 3.2.1.41 pullulanase intracellular - 5622 721313 3.2.1.43 beta-L-rhamnosidase intracellular - 5622 136443 3.2.1.48 sucrose alpha-glucosidase intracellular - 5622 655295 3.2.1.48 sucrose alpha-glucosidase intracellular Intracellular sucrase activity, remaining more or less constant around 75 nmoles/200000000cells for up to 3 h 5622 -, 715207 3.2.1.51 alpha-L-fucosidase intracellular - 5622 136753, 752101 3.2.1.52 beta-N-acetylhexosaminidase intracellular the fungus has the ability to store a high amount of EXC1Y in an active form and secrete it into the medium later 5622 655285 3.2.1.54 cyclomaltodextrinase intracellular - 5622 -, 136609, 136612, 664779 3.2.1.55 non-reducing end alpha-L-arabinofuranosidase intracellular - 5622 -, 288826, 288835, 288843, 677763 3.2.1.58 glucan 1,3-beta-glucosidase intracellular - 5622 136642, 739423 3.2.1.65 levanase intracellular small extent transported into periplasmic space 5622 136760 3.2.1.67 galacturonan 1,4-alpha-galacturonidase intracellular - 5622 -, 136778, 747730 3.2.1.7 inulinase intracellular - 5622 -, 749601 3.2.1.71 glucan endo-1,2-beta-glucosidase intracellular highly bound 5622 208781 3.2.1.75 glucan endo-1,6-beta-glucosidase intracellular - 5622 -, 136867 3.2.1.8 endo-1,4-beta-xylanase intracellular - 5622 -, 171638, 717395 3.2.1.8 endo-1,4-beta-xylanase intracellular 1.4% of the total xylanase activity 5622 -, 171656 3.2.1.81 beta-agarase intracellular - 5622 -, 136871, 705484 3.2.1.84 glucan 1,3-alpha-glucosidase intracellular - 5622 -, 725283 3.2.1.96 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase intracellular recombinant enzyme produced in Escherichia coli appears both in the periplasmic space and in the cell 5622 171692 3.2.1.B36 maltose-forming alpha-amylase intracellular - 5622 -, 727388 3.2.2.5 NAD+ glycohydrolase intracellular - 5622 656169 3.3.2.6 leukotriene-A4 hydrolase intracellular - 5622 752451 3.4.11.1 leucyl aminopeptidase intracellular - 5622 679197, 732461 3.4.11.10 bacterial leucyl aminopeptidase intracellular - 5622 -, 663559, 665203 3.4.11.16 Xaa-Trp aminopeptidase intracellular cells expressing the enzyme intracellularly do not necessarily express it at the surface 5622 643873 3.4.11.2 membrane alanyl aminopeptidase intracellular - 5622 35869, 663559 3.4.11.2 membrane alanyl aminopeptidase intracellular the enzyme contains no secretion signal sequence 5622 665114 3.4.11.24 aminopeptidase S intracellular - 5622 663559 3.4.11.7 glutamyl aminopeptidase intracellular in CHO cells, mutant enzyme N353D 5622 654587 3.4.11.B3 Sulfolobus solfataricus aminopeptidase intracellular - 5622 718953 3.4.11.B7 arginyl aminopeptidase PH1704 intracellular - 5622 -, 730838 3.4.13.9 Xaa-Pro dipeptidase intracellular - 5622 652035 3.4.13.9 Xaa-Pro dipeptidase intracellular dipeptidase function 5622 683061 3.4.14.11 Xaa-Pro dipeptidyl-peptidase intracellular - 5622 -, 36200, 36251, 682997, 755630 3.4.14.5 dipeptidyl-peptidase IV intracellular - 5622 -, 36251 3.4.17.B1 Sulfolobus solfataricus carboxypeptidase intracellular - 5622 -, 651034 3.4.19.9 folate gamma-glutamyl hydrolase intracellular - 5622 647307, 683179, 683368, 683802 3.4.21.103 physarolisin intracellular - 5622 647477, 649268 3.4.21.109 matriptase intracellular - 5622 683674 3.4.21.109 matriptase intracellular acid-induced matriptase activation takes place both on the cell surface and inside the cells, likely due to the parallel intracellular acidification that activates intracellular matriptase 5622 709136 3.4.21.20 cathepsin G intracellular - 5622 709983 3.4.21.34 plasma kallikrein intracellular prekallikrein 5622 683208 3.4.21.5 thrombin intracellular - 5622 717955 3.4.21.62 Subtilisin intracellular - 5622 731819 3.4.21.68 t-Plasminogen activator intracellular tPA activity in both the cellular extract and the supernatant of cultured astrocytes 5622 -, 718168 3.4.21.72 IgA-specific serine endopeptidase intracellular inactive pro-enzyme, the cleaved and maturated protein is secreted 5622 680138 3.4.21.75 Furin intracellular - 5622 708682, 717827 3.4.21.79 granzyme B intracellular - 5622 732275 3.4.21.84 limulus clotting factor C intracellular - 5622 29790 3.4.21.86 Limulus clotting enzyme intracellular zymogen 5622 29794 3.4.21.B52 thermostable serine endopeptidase (Sulfolobus) intracellular - 5622 -, 651211, 718954 3.4.21.B58 pernilase intracellular - 5622 -, 727450 3.4.22.26 cancer procoagulant intracellular - 5622 710603 3.4.22.34 Legumain intracellular crude worm protein extracts but not in excretion-secretion products of adult parasites, polyclonal antisera and activity assay 5622 683856 3.4.22.40 bleomycin hydrolase intracellular - 5622 36720, 649347, 669481 3.4.22.43 cathepsin V intracellular - 5622 669257 3.4.22.43 cathepsin V intracellular the corneal enzyme stays within cells and is not secreted 5622 137269 3.4.22.52 calpain-1 intracellular - 5622 696290 3.4.22.54 calpain-3 intracellular - 5622 755076 3.4.22.B20 PfpI endopeptidase intracellular - 5622 647388 3.4.22.B27 calpain 7 intracellular - 5622 731800 3.4.22.B30 calpain 10 intracellular - 5622 717063 3.4.22.B31 calpain 11 intracellular - 5622 648408 3.4.22.B77 Sulfolobus solfataricus peptidase intracellular - 5622 -, 718770 3.4.23.15 renin intracellular - 5622 667164, 95752 3.4.23.15 renin intracellular active renin is significantly higher in the cell lysate than in culture medium. Inactive prorenin is similar for the intracellular and extracellular compartments. Free active renin is the predominant form found in both cell compartments. Mesangial cells in culture are able to synthesize and translate renin mRNA probably as inactive prorenin which is mostly processed to active renin inside the cells. The cells secrete both forms of the enzyme but at lower level compared with intracellular content 5622 650745 3.4.23.23 Mucorpepsin intracellular - 5622 30649 3.4.23.24 Candidapepsin intracellular - 5622 30692 3.4.23.34 cathepsin E intracellular - 5622 651797, 677973 3.4.23.34 cathepsin E intracellular non-lysosomal proteinase 5622 30779, 30793, 30803 3.4.24.12 envelysin intracellular - 5622 36978 3.4.24.15 thimet oligopeptidase intracellular - 5622 -, 683026 3.4.24.15 thimet oligopeptidase intracellular intracellular EP24.15 is present throughout the cell, both cytosolic and particulate, with less nuclear localization and no co-localization with either the endoplasmatic reticulum marker calnexin or Golgi marker GM130, overview 5622 683813 3.4.24.17 stromelysin 1 intracellular - 5622 733275 3.4.24.23 matrilysin intracellular mucosal and tumor tissue 5622 683323 3.4.24.23 matrilysin intracellular pro-MMP-7 is diffusely distributed in epithelial cells of the endometrium, while the mature enzyme is located at the plasma membrane 5622 683345 3.4.24.36 leishmanolysin intracellular - 5622 -, 683418 3.4.24.36 leishmanolysin intracellular about two-thirds of newly synthesized enzyme becomes surface localized, the rest of enzyme does not reach the cell surface. Internal enzyme is stable without detectable decrease in abundance up to 6 days after biosynthesis 5622 670182 3.4.24.40 serralysin intracellular and extracellular 5622 696410 3.4.24.65 macrophage elastase intracellular - 5622 709559 3.4.24.87 ADAMTS13 endopeptidase intracellular - 5622 713534 3.4.24.B15 PHEX peptidase intracellular in squamous cell carcinoma cells 5622 753827 3.4.24.B3 matrix metalloproteinase-11 intracellular - 5622 754241 3.4.24.B4 matrix metalloproteinase-13 intracellular in cartilage 5622 712838 3.5.1.1 asparaginase intracellular - 5622 686239 3.5.1.1 asparaginase intracellular localized external to the cytoplasmic membrane 5622 -, 208951 3.5.1.11 penicillin amidase intracellular - 5622 171887, 171888, 171903, 171912, 712781, 753335, 755223 3.5.1.14 N-acyl-aliphatic-L-amino acid amidohydrolase intracellular - 5622 288867 3.5.1.19 nicotinamidase intracellular internal location 5622 246587 3.5.1.2 glutaminase intracellular enzyme from strain MA-27-IM 5622 669542 3.5.1.22 pantothenase intracellular - 5622 171976 3.5.1.23 ceramidase intracellular - 5622 734448 3.5.1.23 ceramidase intracellular recombinant CDase expressed in Escherichia coli DH5alpha and BL21 5622 657260 3.5.1.24 choloylglycine hydrolase intracellular - 5622 209046 3.5.1.26 N4-(beta-N-acetylglucosaminyl)-L-asparaginase intracellular - 5622 209054 3.5.1.28 N-acetylmuramoyl-L-alanine amidase intracellular - 5622 654534 3.5.1.28 N-acetylmuramoyl-L-alanine amidase intracellular recombinant PGRP-L shows primarily intracellular and cell surface location 5622 656179 3.5.1.41 chitin deacetylase intracellular - 5622 -, 669737 3.5.1.42 nicotinamide-nucleotide amidase intracellular - 5622 209136 3.5.1.46 6-aminohexanoate-oligomer exohydrolase intracellular - 5622 -, 172039, 172040, 172041, 172043 3.5.1.47 N-acetyldiaminopimelate deacetylase intracellular - 5622 172044, 172045 3.5.1.5 urease intracellular - 5622 685779 3.5.1.72 D-benzoylarginine-4-nitroanilide amidase intracellular - 5622 -, 209232 3.5.1.9 arylformamidase intracellular - 5622 209244, 209245, 209246 3.5.1.93 glutaryl-7-aminocephalosporanic-acid acylase intracellular - 5622 -, 661389 3.5.1.97 acyl-homoserine-lactone acylase intracellular PfmA lacks an N-terminal signal peptide and no activity is found in the cell medium 5622 -, 757621 3.5.2.6 beta-lactamase intracellular - 5622 -, 209340 3.5.4.2 adenine deaminase intracellular - 5622 172179, 696861 3.5.4.2 adenine deaminase intracellular probably cytosol 5622 172173 3.5.5.1 nitrilase intracellular - 5622 -, 758526 3.5.5.7 Aliphatic nitrilase intracellular - 5622 -, 655149, 670792 3.6.1.23 dUTP diphosphatase intracellular - 5622 670909 3.6.1.5 apyrase intracellular - 5622 756376 3.6.1.5 apyrase intracellular associated with membrane 5622 656001 3.7.1.2 fumarylacetoacetase intracellular - 5622 289245, 289246, 289247 3.7.1.4 phloretin hydrolase intracellular in galectin-3 knock-out mutant, not in wild-type (immunostaining) 5622 -, 699107 4.1.1.12 aspartate 4-decarboxylase intracellular - 5622 3964 4.1.1.15 glutamate decarboxylase intracellular - 5622 -, 655656, 749272 4.1.1.15 glutamate decarboxylase intracellular intracellular GAD system, GADi 5622 -, 726722 4.1.1.17 ornithine decarboxylase intracellular - 5622 697861 4.1.1.2 oxalate decarboxylase intracellular - 5622 -, 651021 4.1.1.2 oxalate decarboxylase intracellular localized close to the plasma membrane and in intracellular vesicles 5622 4106 4.1.1.22 histidine decarboxylase intracellular - 5622 665185 4.1.1.35 UDP-glucuronate decarboxylase intracellular lumenal orientation 5622 4405 4.1.1.36 phosphopantothenoylcysteine decarboxylase intracellular not bound to any cellular structure 5622 4408 4.1.1.4 acetoacetate decarboxylase intracellular - 5622 -, 4523 4.1.1.62 gentisate decarboxylase intracellular - 5622 4728 4.1.1.75 5-guanidino-2-oxopentanoate decarboxylase intracellular - 5622 4829 4.1.1.8 oxalyl-CoA decarboxylase intracellular whole-cell degrades oxalate while the cell-free culture supernatant does not 5622 653142 4.1.2.9 phosphoketolase intracellular - 5622 37323 4.1.99.16 geosmin synthase intracellular - 5622 -, 728186 4.1.99.2 tyrosine phenol-lyase intracellular - 5622 726700 4.2.1.1 carbonic anhydrase intracellular - 5622 33582, 33584, 716685 4.2.1.84 nitrile hydratase intracellular - 5622 -, 648422, 648423 4.2.2.11 guluronate-specific alginate lyase intracellular - 5622 -, 705481 4.2.2.11 guluronate-specific alginate lyase intracellular most of the alginate lyase activity is intracellular 5622 648523 4.2.2.2 pectate lyase intracellular more than 86% of the pectate lyase protein is present in the active state at pH 8 5622 -, 681783 4.2.2.3 mannuronate-specific alginate lyase intracellular - 5622 -, 34078, 648532 4.2.2.3 mannuronate-specific alginate lyase intracellular constitutive expression, intracellular isozymes also show hydrolase activity on alginate 5622 648532 4.2.2.3 mannuronate-specific alginate lyase intracellular recombinant enzyme 5622 -, 648532 4.2.2.7 heparin lyase intracellular - 5622 -, 693981, 713782 4.2.2.7 heparin lyase intracellular the fungus produces heparinase, both extracellularly and intracellularly, in its late log phase of growth 5622 693981 4.3.2.2 adenylosuccinate lyase intracellular - 5622 -, 728121 4.3.3.7 4-hydroxy-tetrahydrodipicolinate synthase intracellular - 5622 715195 4.4.1.11 methionine gamma-lyase intracellular - 5622 -, 701880 4.4.1.3 dimethylpropiothetin dethiomethylase intracellular - 5622 34604 4.6.1.19 ribonuclease T2 intracellular epidermal cells of lateral and adventitious root primordia 5622 681125 4.6.1.22 Bacillus subtilis ribonuclease intracellular lysosome 5622 134516 4.6.1.22 Bacillus subtilis ribonuclease intracellular not extracellular Rnase 5622 134516 5.1.1.4 proline racemase intracellular in replicative non-infective forms of Trypanosoma cruzi 5622 652377 5.1.1.4 proline racemase intracellular TcPRACB secretes the intracellular isoform of the enzyme. TcPRACA gene can generate both secreted and intracellular isoforms (by an alternative trans-splicing mechanism) 5622 662908 5.1.3.3 Aldose 1-epimerase intracellular isoform aep1, predicted gene location, there is no galactomutarotase activity present in Hypocrea jecorina when growing on lactose 5622 694901 5.1.3.3 Aldose 1-epimerase intracellular isoform aep2, predicted gene location, there is no galactomutarotase activity present in Hypocrea jecorina when growing on lactose 5622 694901 5.2.1.8 peptidylprolyl isomerase intracellular - 5622 728483 5.2.1.8 peptidylprolyl isomerase intracellular enzyme EF2898 5622 727618 5.4.99.11 isomaltulose synthase intracellular - 5622 3467 5.4.99.5 chorismate mutase intracellular - 5622 -, 703449 6.3.2.2 glutamate-cysteine ligase intracellular - 5622 745734 7.2.2.10 P-type Ca2+ transporter intracellular the enzyme is intracellular in epidermal keratinocytes 5622 718751 7.2.2.13 Na+/K+-exchanging ATPase intracellular rapid translocation for short-term regulation between membrane and intracellular compartments 5622 673611 7.2.2.19 H+/K+-exchanging ATPase intracellular labeling density of H+/K+-ATPase is 4fold higher on the intracellular canliculi membrane of histamine stimulated parietal cells than on that of resting parietal cells, in cimetidine-treated glands on the apical microvillar membranes of intracellular canliculi 5622 675189 7.2.2.8 P-type Cu+ transporter intracellular - 5622 -, 734718 7.2.2.8 P-type Cu+ transporter intracellular TgCuTP localizes to intraparasitic structures juxtaposed to the acidocalcisomes and/or plant-like vacuole 5622 734718 7.6.2.1 P-type phospholipid transporter intracellular - 5622 751691