1.1.1.26 glyoxylate reductase peroxisome - 5777 286418, 737745, 762165 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase peroxisome - 5777 286473 1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase peroxisome - 5777 723896, 763054 1.1.1.29 glycerate dehydrogenase peroxisome - 5777 286509, 726102, 728436, 737736, 737745, 762162, 762165 1.1.1.300 NADP-retinol dehydrogenase peroxisome - 5777 687139, 690876 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase peroxisome - 5777 286601 1.1.1.36 acetoacetyl-CoA reductase peroxisome - 5777 652075, 687492 1.1.1.37 malate dehydrogenase peroxisome - 5777 -, 286628, 286653, 286672, 286676, 689534, 700816, 760377 1.1.1.41 isocitrate dehydrogenase (NAD+) peroxisome - 5777 -, 762313 1.1.1.42 isocitrate dehydrogenase (NADP+) peroxisome - 5777 -, 711006, 722338, 741388, 761477 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) peroxisome - 5777 660941, 741438, 761625 1.1.1.81 hydroxypyruvate reductase peroxisome - 5777 737745 1.1.1.98 (R)-2-hydroxy-fatty-acid dehydrogenase peroxisome - 5777 287560 1.1.1.99 (S)-2-hydroxy-fatty-acid dehydrogenase peroxisome - 5777 287560 1.1.3.13 alcohol oxidase peroxisome - 5777 484914, 484915, 673755, 686817, 695721, 741256 1.1.3.15 (S)-2-hydroxy-acid oxidase peroxisome - 5777 -, 287560, 389677, 389680, 389681, 389682, 389684, 389687, 389694, 389697, 671994, 673694, 677109, 677279, 698951, 700821, 723811, 724535, 741999, 745481, 745737, 745815, 763461 1.1.3.2 L-lactate oxidase peroxisome - 5777 -, 745729 1.1.3.20 long-chain-alcohol oxidase peroxisome - 5777 -, 740470 1.1.3.27 hydroxyphytanate oxidase peroxisome - 5777 389759, 389760, 389761 1.1.3.4 glucose oxidase peroxisome - 5777 389813 1.11.1.11 L-ascorbate peroxidase peroxisome - 5777 689652, 697013, 700220, 700703, 765656 1.11.1.21 catalase-peroxidase peroxisome - 5777 -, 765406 1.11.1.24 thioredoxin-dependent peroxiredoxin peroxisome - 5777 655981, 656491 1.11.1.6 catalase peroxisome - 5777 -, 439775, 439781, 439791, 725156 1.11.1.9 glutathione peroxidase peroxisome - 5777 396645 1.13.12.7 firefly luciferase peroxisome - 5777 484857, 658709 1.14.11.1 gamma-butyrobetaine dioxygenase peroxisome - 5777 439299 1.14.11.18 phytanoyl-CoA dioxygenase peroxisome - 5777 285264, 285265, 285268, 285271, 658877, 659669, 674512 1.14.14.18 heme oxygenase (biliverdin-producing) peroxisome - 5777 659620 1.14.15.15 cholestanetriol 26-monooxygenase peroxisome - 5777 439031 1.14.15.7 choline monooxygenase peroxisome - 5777 726250 1.17.99.3 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase peroxisome - 5777 391048, 657715, 657798, 657799, 658589, 658691, 659122 1.2.1.19 aminobutyraldehyde dehydrogenase peroxisome - 5777 742521, 743820, 763552 1.2.1.48 long-chain-aldehyde dehydrogenase peroxisome - 5777 347796, 390323, 763641 1.2.1.8 betaine-aldehyde dehydrogenase peroxisome - 5777 700697, 712013, 726249, 740510, 741394, 762849 1.2.1.84 alcohol-forming fatty acyl-CoA reductase peroxisome - 5777 656242, 763306 1.2.3.4 oxalate oxidase peroxisome - 5777 288386 1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) peroxisome - 5777 349076 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] peroxisome - 5777 390711, 390719, 685405, 690046, 700872, 745258, 758835, 759440, 759455 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing] peroxisome - 5777 390725, 725482 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH) peroxisome - 5777 390760, 673644 1.3.3.6 acyl-CoA oxidase peroxisome - 5777 -, 391039, 391041, 391042, 391043, 391044, 391045, 391046, 391047, 391048, 391049, 391052, 391053, 391054, 391057, 391058, 391061, 391063, 391064, 391066, 391067, 391068, 391069, 391070, 391071, 391072, 655280, 655671, 657279, 672370, 673719, 673774, 674357, 676339, 684293, 686539, 689558, 689649, 700546, 712822, 712913, 724805, 726186, 745377, 764225, 764720 1.3.8.7 medium-chain acyl-CoA dehydrogenase peroxisome - 5777 391338 1.4.1.4 glutamate dehydrogenase (NADP+) peroxisome - 5777 -, 763355 1.4.3.1 D-aspartate oxidase peroxisome - 5777 -, 391706, 391719, 656415, 711719, 711721 1.4.3.2 L-amino-acid oxidase peroxisome - 5777 391769, 391794 1.4.3.21 primary-amine oxidase peroxisome - 5777 -, 391949, 391956, 742600 1.4.3.3 D-amino-acid oxidase peroxisome - 5777 391834, 391853, 391864, 656415, 686020, 686277, 686831, 689217, 699644, 699761, 699830, 700451, 701073, 711718, 712324, 723920, 741796, 763091 1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] peroxisome - 5777 743355 1.5.1.25 thiomorpholine-carboxylate dehydrogenase peroxisome - 5777 743355 1.5.3.13 N1-acetylpolyamine oxidase peroxisome - 5777 764138, 764331, 765150 1.5.3.16 spermine oxidase peroxisome - 5777 694651 1.5.3.17 non-specific polyamine oxidase peroxisome - 5777 -, 694651, 723919, 724126, 725625, 742588, 764331 1.5.3.25 fructosyl amine oxidase (glucosone-forming) peroxisome - 5777 763944 1.5.3.7 L-pipecolate oxidase peroxisome - 5777 392475, 392476, 743036 1.6.5.4 monodehydroascorbate reductase (NADH) peroxisome - 5777 676498, 676536, 676573, 743001, 743436 1.7.3.3 factor-independent urate hydroxylase peroxisome - 5777 394154, 394168, 394172, 394175, 394177, 673545, 675091, 765701 1.8.1.7 glutathione-disulfide reductase peroxisome - 5777 676198 1.8.3.1 sulfite oxidase peroxisome - 5777 393031, 659599, 660516, 667207, 669515, 670497, 694617, 698956, 712146, 712624, 743565, 764788, 765870 1.8.5.1 glutathione dehydrogenase (ascorbate) peroxisome - 5777 -, 765156, 765592, 765593 2.2.1.1 transketolase peroxisome - 5777 675191 2.2.1.2 transaldolase peroxisome - 5777 -, 756247 2.2.1.3 formaldehyde transketolase peroxisome - 5777 -, 486048, 486052, 756248 2.3.1.137 carnitine O-octanoyltransferase peroxisome - 5777 -, 486292, 486294, 486295, 486297, 486298, 486299, 486300, 486301, 486304, 486305, 486306, 486307, 486308, 486309, 659372, 686028, 718746 2.3.1.155 acetyl-CoA C-myristoyltransferase peroxisome - 5777 -, 288678, 288681, 288682 2.3.1.16 acetyl-CoA C-acyltransferase peroxisome - 5777 288674, 288675, 288676, 288677, 288678, 486422, 486424, 486437, 658349, 674357, 675383, 676105, 719874 2.3.1.164 isopenicillin-N N-acyltransferase peroxisome - 5777 686918 2.3.1.176 propanoyl-CoA C-acyltransferase peroxisome - 5777 661716, 662092, 662586, 685342, 758130 2.3.1.21 carnitine O-palmitoyltransferase peroxisome - 5777 486525, 486527, 486534, 486549, 688981 2.3.1.42 glycerone-phosphate O-acyltransferase peroxisome - 5777 -, 486338, 486952, 486953, 486954, 486956, 486957, 486958, 486969, 486971, 486972, 486973, 659671, 672439, 736453, 756338 2.3.1.65 bile acid-CoA:amino acid N-acyltransferase peroxisome - 5777 659664, 673916, 757369 2.3.1.7 carnitine O-acetyltransferase peroxisome - 5777 -, 486295, 487404, 487406, 487407, 487408, 487410, 487411, 487413, 487415, 487416, 487417, 487421, 487422, 487423, 487424, 487425, 487426, 487427, 487429, 487430, 487431, 487432, 659194, 659815, 735697 2.3.1.9 acetyl-CoA C-acetyltransferase peroxisome - 5777 -, 288676, 487699, 736771 2.3.1.B43 protein-lysine desuccinylase (NAD+) peroxisome - 5777 756522 2.3.3.16 citrate synthase (unknown stereospecificity) peroxisome - 5777 488068, 660134 2.3.3.9 malate synthase peroxisome - 5777 670169 2.5.1.10 (2E,6E)-farnesyl diphosphate synthase peroxisome - 5777 723047, 737749 2.5.1.21 squalene synthase peroxisome - 5777 489840, 697143 2.5.1.26 alkylglycerone-phosphate synthase peroxisome - 5777 489882, 489886, 489887, 489888, 489896, 723024 2.5.1.39 4-hydroxybenzoate polyprenyltransferase peroxisome - 5777 637004 2.6.1.4 glycine transaminase peroxisome - 5777 639988 2.6.1.44 alanine-glyoxylate transaminase peroxisome - 5777 -, 640065, 640069, 640073, 640075, 640076, 640078, 640079, 640080, 640081, 640082, 640083, 640086, 640087, 640088, 663117, 663312, 671206, 676030, 685389, 689026, 689893, 701547, 704634, 721240, 721718, 721754, 722393, 722812, 723487, 723562, 723614, 739610, 758763, 758860 2.6.1.45 serine-glyoxylate transaminase peroxisome - 5777 -, 636689, 636690, 636700, 657439, 759565 2.6.1.51 serine-pyruvate transaminase peroxisome - 5777 -, 640077, 640082, 640138, 640139, 640141, 640142, 640143, 640144, 640146, 640148, 658995 2.6.1.60 aromatic-amino-acid-glyoxylate transaminase peroxisome - 5777 637008 2.7.1.137 phosphatidylinositol 3-kinase peroxisome - 5777 760661 2.7.1.83 pseudouridine kinase peroxisome - 5777 762128 3.1.1.28 acylcarnitine hydrolase peroxisome - 5777 -, 649489 3.1.1.5 lysophospholipase peroxisome - 5777 716535 3.1.2.1 acetyl-CoA hydrolase peroxisome - 5777 750619, 94490, 94492, 94493 3.1.2.18 ADP-dependent short-chain-acyl-CoA hydrolase peroxisome - 5777 646115, 686028 3.1.2.2 palmitoyl-CoA hydrolase peroxisome - 5777 646115, 646136, 646138, 646141, 646144, 646151, 646155, 646156, 646162, 646164, 646170, 646172, 646190, 646193, 646201, 94478 3.1.2.20 acyl-CoA hydrolase peroxisome - 5777 646115, 646136, 646138, 646141, 646144, 646151, 646155, 646156, 646162, 646164, 646170, 646172, 646190, 646193, 646201, 665707, 679724, 686028, 94478 3.1.2.27 choloyl-CoA hydrolase peroxisome - 5777 646200, 657550, 660497 3.1.2.28 1,4-dihydroxy-2-naphthoyl-CoA hydrolase peroxisome - 5777 730609 3.1.2.3 succinyl-CoA hydrolase peroxisome - 5777 665676 3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase peroxisome - 5777 710015 3.1.3.21 glycerol-1-phosphatase peroxisome - 5777 729762 3.1.3.66 phosphatidylinositol-3,4-bisphosphate 4-phosphatase peroxisome - 5777 679841 3.2.1.147 thioglucosidase peroxisome - 5777 -, 755037 3.3.2.10 soluble epoxide hydrolase peroxisome - 5777 208928, 662565, 708022, 731877 3.4.18.1 cathepsin X peroxisome - 5777 696995 3.4.21.53 Endopeptidase La peroxisome - 5777 -, 710314, 753718 3.4.22.27 cathepsin S peroxisome - 5777 696995 3.4.24.56 insulysin peroxisome - 5777 654006, 683342, 683920, 710682 3.5.1.116 ureidoglycolate amidohydrolase peroxisome - 5777 34479 3.5.2.17 hydroxyisourate hydrolase peroxisome - 5777 644455 3.5.2.5 allantoinase peroxisome - 5777 246652, 246666 3.5.3.9 allantoate deiminase peroxisome - 5777 689608 3.6.1.22 NAD+ diphosphatase peroxisome - 5777 654332, 758387 3.6.4.7 peroxisome-assembly ATPase peroxisome - 5777 -, 701006, 733235, 734186, 734571, 734883, 734948, 755919, 756224, 757199, 757772, 758016 3.6.5.5 dynamin GTPase peroxisome - 5777 686581, 687638 4.1.1.33 diphosphomevalonate decarboxylase peroxisome - 5777 678380, 728536 4.1.1.47 tartronate-semialdehyde synthase peroxisome - 5777 727247 4.1.1.9 malonyl-CoA decarboxylase peroxisome - 5777 690446, 727260, 727943, 728812 4.1.2.63 2-hydroxyacyl-CoA lyase peroxisome - 5777 760472, 760544, 760613, 760615, 760638, 761438, 761949, 762299 4.1.3.1 isocitrate lyase peroxisome - 5777 -, 33119, 670169, 679367, 705567 4.1.3.36 1,4-dihydroxy-2-naphthoyl-CoA synthase peroxisome - 5777 704888 4.1.3.4 hydroxymethylglutaryl-CoA lyase peroxisome - 5777 649475, 681959 4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase peroxisome - 5777 657540, 657714, 657721, 684952 4.2.1.119 enoyl-CoA hydratase 2 peroxisome - 5777 -, 33737, 680715, 684455, 684952, 687492, 689308, 696077, 714098, 730243, 730244, 747869 4.2.1.17 enoyl-CoA hydratase peroxisome - 5777 649739, 684952, 696077, 704681, 715522, 730242, 746582 4.2.1.74 medium-chain-enoyl-CoA hydratase peroxisome - 5777 694522 4.3.1.24 phenylalanine ammonia-lyase peroxisome - 5777 34334 4.3.2.3 ureidoglycolate lyase peroxisome - 5777 34470 5.1.2.3 3-hydroxybutyryl-CoA epimerase peroxisome - 5777 2211, 2212 5.1.99.4 alpha-methylacyl-CoA racemase peroxisome - 5777 649732, 680093, 681308, 681814, 682220, 701681, 703387, 704836, 705416, 706046, 727322 5.3.3.2 isopentenyl-diphosphate DELTA-isomerase peroxisome - 5777 2934, 680882, 728493 5.3.3.21 DELTA3,5-DELTA2,4-dienoyl-CoA isomerase peroxisome - 5777 -, 744206, 745258, 745264, 745267, 746100, 746519 5.3.3.3 vinylacetyl-CoA DELTA-isomerase peroxisome - 5777 2967 5.3.3.8 DELTA3-DELTA2-enoyl-CoA isomerase peroxisome - 5777 -, 2997, 3005, 3008, 3011, 3014, 649676, 651339, 651909, 661257, 661258, 744209, 746625, 747727, 747742 5.6.2.3 DNA 5'-3' helicase peroxisome - 5777 757877 6.2.1.14 6-carboxyhexanoate-CoA ligase peroxisome - 5777 632 6.2.1.24 phytanate-CoA ligase peroxisome - 5777 705 6.2.1.3 long-chain-fatty-acid-CoA ligase peroxisome - 5777 658709, 663057, 672419, 674830, 693420, 728689, 738, 746245, 752 6.2.1.B3 OPC-8:CoA ligase peroxisome - 5777 693420, 722649, 728532 6.3.2.26 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase peroxisome - 5777 706449 7.6.2.4 ABC-type fatty-acyl-CoA transporter peroxisome - 5777 -, 210404, 210406, 210407, 210408, 210411, 656347, 667893, 720022 1.11.1.6 catalase peroxisome 80% of the total activity 5777 439800 3.3.2.10 soluble epoxide hydrolase peroxisome a recombinant modified enzyme in HeLa cells, recombinant wild-type enzyme and recombinant modified enzyme in plant BY-2 cells 5777 661717 3.3.2.10 soluble epoxide hydrolase peroxisome a recombinant modified enzyme in V79 cells 5777 661717 2.6.1.1 aspartate transaminase peroxisome AAT-2: major isoenzyme in mitochondria and peroxisomes, very low activity of AAT-1 5777 639819 7.6.2.4 ABC-type fatty-acyl-CoA transporter peroxisome ABC transporter ALDP interacts with ACLY and FATP4, ABC transporter PMP70 interacts with FASN and FATP4 involved in fatty acid metabolism, thus constituting a fatty acid synthesis-transport machinery at the cytoplasmic side of the peroxisomal membrane 5777 720023 2.3.3.9 malate synthase peroxisome abundant cells grown on oleic acid 5777 638503 2.6.1.44 alanine-glyoxylate transaminase peroxisome AGT is synthetized and folded in the cell cytosol before being imported into peroxisomes via the interaction with the Pex5p carrier 5777 759584 1.1.3.15 (S)-2-hydroxy-acid oxidase peroxisome an N-terminal fluorescent fusion protein colocalizes with an peroxisomal marker in tobacco protoplasts 5777 763602 2.6.1.44 alanine-glyoxylate transaminase peroxisome apoenzyme in the peroxisomes, holoenzyme in the mitochondrion 5777 640074 1.11.1.11 L-ascorbate peroxidase peroxisome APX4, APX5 5777 700220 2.5.1.26 alkylglycerone-phosphate synthase peroxisome at least the active site of the integral membrane protein is localized exclusively at the inner surface of the peroxisomal membrane 5777 486965 1.5.3.16 spermine oxidase peroxisome AtPAO4 is the major isoform in root peroxisomes 5777 694651 3.6.4.7 peroxisome-assembly ATPase peroxisome AWP1 interacts with Pex6 on the peroxisome 5777 721087 1.2.1.8 betaine-aldehyde dehydrogenase peroxisome BADH1 5777 700697 2.3.1.164 isopenicillin-N N-acyltransferase peroxisome both native and recombinant enzyme 5777 673752 5.1.99.4 alpha-methylacyl-CoA racemase peroxisome bulk activity 5777 2447 1.1.1.184 carbonyl reductase (NADPH) peroxisome C-terminal peroxisomal targeting sequence 1 of each subunit is involved in intersubunit interactions and buried in the interior of the tetrameric enzyme 5777 690091 2.3.1.42 glycerone-phosphate O-acyltransferase peroxisome catalytic site at inner surface of peroxisomal membrane 5777 486964, 486965, 486974 3.4.21.53 Endopeptidase La peroxisome cells overexpressing lon contain large peroxisomes, but number of peroxisomes in these cells are less than that in wild-type cells 5777 680569 3.4.24.56 insulysin peroxisome cloned cDNAs of insulin degrading enzyme (human, rat and Drosophila melanogaster) reveal a deduced classical peroxisomal targeting sequence A/SKL at their carboxyl termini, this may account for the peroxisomal location of the enzyme 5777 31331 3.1.1.31 6-phosphogluconolactonase peroxisome co-localization with thioredoxin m-type, Trx_m2 5777 730428 2.3.1.164 isopenicillin-N N-acyltransferase peroxisome colocalization of isopenicillin N-acyltransferase and phenylacetyl-CoA ligase 5777 -, 661021 1.1.3.15 (S)-2-hydroxy-acid oxidase peroxisome confocal immunofluorescence microscopy reveals that capsid protein P8 is colocalized with GOX in peroxisomes 5777 673694 4.1.1.33 diphosphomevalonate decarboxylase peroxisome contains a small amount of the 45000 Da enzyme species, but not the 37000 Da species. The 45000 Da enzyme species is localized in the matrix 5777 650488 6.2.1.3 long-chain-fatty-acid-CoA ligase peroxisome cytoplasmic side of the peroxisomal membrane 5777 757 4.2.1.119 enoyl-CoA hydratase 2 peroxisome D-specific 2-trans-enoyl-CoA hydratase is exclusively located in 5777 697692 1.4.3.1 D-aspartate oxidase peroxisome DDO-1 5777 711718, 711719 2.4.2.22 xanthine phosphoribosyltransferase peroxisome deletion of the peroxisomal targeting sequence is not required for activity 5777 659904 3.1.2.12 S-formylglutathione hydrolase peroxisome detection of recombinant GFP-fusion protein 5777 653164 5.3.3.8 DELTA3-DELTA2-enoyl-CoA isomerase peroxisome determined by producing constructs between enhanced yellow fluorescent protein (EYFP) at the N-terminus and the AtECI proteins at the C-terminus. The localization of EYFP-AtECI1 and EYFP-AtECI2 indicate that AtECI1 and AtECI2 are peroxisomal proteins. The EYFP-AtECI3 construct results in diffuse fluorescence throughout the cytosol and nucleus, indicating the absence of peroxisomal targeting. AtECI1, AtECI2, and AtECI3 show high overall homology to peroximal mammalian isomerases, but have only one coserved glutamate reisdue in an position similar to that in the mitochondrial isoemrases 5777 694684 4.3.2.3 ureidoglycolate lyase peroxisome detoxification of the reaction product glyoxylate in the peroxisomes by the malate synthase reaction 5777 34469 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) peroxisome dual localization to cytosol and peroxisomes 5777 722302 1.1.3.38 vanillyl-alcohol oxidase peroxisome dual location: in peroxisomes and in cytosol 5777 10667 3.6.5.5 dynamin GTPase peroxisome dynamin-related protein 1, DRP1 5777 720524 5.3.3.8 DELTA3-DELTA2-enoyl-CoA isomerase peroxisome ECI and MFE1 5777 652357 2.5.1.26 alkylglycerone-phosphate synthase peroxisome entire enzyme is located inside peroxisomes 5777 489890 1.1.1.36 acetoacetyl-CoA reductase peroxisome enzyme contains a C-terminal peroxisomal targeting signal sequence 5777 657366 7.6.2.4 ABC-type fatty-acyl-CoA transporter peroxisome enzyme contains six membrane-spanning segments and a putative ATP-binding domain, the C-terminal hydrophilic domain of the enzyme is on the cytoplasmic surface of peroxisomes 5777 210405 1.11.1.6 catalase peroxisome enzyme contains the peroxisome-PTS-1-targeting signal 5777 -, 657421 4.2.1.119 enoyl-CoA hydratase 2 peroxisome enzyme different from microsomal hydratase 2 though their kinetic properties are similar. They differ in immunological data, subunit size, and chromatographic behaviour, the peroxisomal isoform is not recognized by the antibody to its microsomal counterpart 5777 5870 4.1.3.4 hydroxymethylglutaryl-CoA lyase peroxisome enzyme differs from mitochondrial enzyme according to immunoreactivity and other properties, mitochondrial leader sequence influences quaternary structure 5777 5369 2.5.1.26 alkylglycerone-phosphate synthase peroxisome enzyme is not an integral membrane protein 5777 489894 4.6.1.14 glycosylphosphatidylinositol diacylglycerol-lyase peroxisome enzyme is translocated from glycosomes to the endoplasmic reticulum when cells are treated with mild alkaline or hypo-osmotic conditions 5777 -, 679738 4.1.1.9 malonyl-CoA decarboxylase peroxisome enzyme may be targeted to peroxisomes in addition to, or possibly instead of, mitochondria 5777 652698 2.7.4.2 phosphomevalonate kinase peroxisome exclusive localisation 5777 -, 723054 5.3.3.8 DELTA3-DELTA2-enoyl-CoA isomerase peroxisome exclusively localized in 5777 3020 1.3.3.6 acyl-CoA oxidase peroxisome existence of two independent, Pex5p-mediated import pathways into peroxisomes in yeast: 1. a classical peroxisomal targeting signal 1 pathway and a novel, non-PTS1 pathway for Pox1p 5777 656057 6.2.1.3 long-chain-fatty-acid-CoA ligase peroxisome FaaB 5777 713991 1.3.3.6 acyl-CoA oxidase peroxisome fluorescent protein-tagging points to a peroxisomal location of CrACX2 5777 746084 1.1.1.37 malate dehydrogenase peroxisome gene YlMDH2 encodes the cytosolic and peroxisomal forms of MDH 5777 721236 2.5.1.18 glutathione transferase peroxisome GFP-tagged recombinant theta class GSTs 5777 704872 3.1.2.18 ADP-dependent short-chain-acyl-CoA hydrolase peroxisome highest activity 5777 94490 3.1.2.27 choloyl-CoA hydrolase peroxisome highest enzyme activity 5777 659661 2.6.1.44 alanine-glyoxylate transaminase peroxisome holoenzyme in the peroxisomes 5777 640074 3.6.4.7 peroxisome-assembly ATPase peroxisome HpPln is localized in peroxisomes in Hansenula polymorpha, subcellular localization study 5777 -, 733235 1.1.1.81 hydroxypyruvate reductase peroxisome HPR! 5777 700736 2.3.1.164 isopenicillin-N N-acyltransferase peroxisome IAT encoded by the aatA gene, containing a peroxisomal targeting signal PTS1 5777 705776 1.1.1.42 isocitrate dehydrogenase (NADP+) peroxisome IDH1 5777 712614, 713508 1.1.1.42 isocitrate dehydrogenase (NADP+) peroxisome IDP3 contains a canonical type I peroxisomal targeting sequence, a carboxyl-terminal Cys-Lys-Leu tripeptide. IDP3 is normally strictly peroxisomal 5777 -, 711006 5.3.3.8 DELTA3-DELTA2-enoyl-CoA isomerase peroxisome in addition to the peroxisomal trifunctional enzyme and the mitochondrial enzyme which shows a preference for short-chain substrates, a separate isomerase with a preference for C10-C12 substrates is observed 5777 3018 1.4.3.3 D-amino-acid oxidase peroxisome in kidney and hepatopancreas 5777 656415 1.17.1.4 xanthine dehydrogenase peroxisome in leaf peroxisomes, the superoxide-generating form, xanthine oxidase XOD is predominant over the xanthine dehydrogenase form XDH, with a XDH/XOD ratio of 0.5. Enzyme is localized to the matrix of peroxisome 5777 688639 3.3.2.10 soluble epoxide hydrolase peroxisome in some cell types sEH shows a dual localisation, both cytosolic and peroxisomal 5777 695933 3.3.2.10 soluble epoxide hydrolase peroxisome in the light mitochondrial fraction 5777 663275 2.3.1.137 carnitine O-octanoyltransferase peroxisome in the peroxisomal CRAT mRNA, there is an in-frame stop codon and translation starts at a downstream second start codon, resulting in a protein that contains 605 amino acids 5777 -, 686028 4.1.1.9 malonyl-CoA decarboxylase peroxisome INS-1 MCD, expression most likely inside, the C-terminal part of enzyme ends with a peroxisomal targeting motif 5777 649668 1.1.3.13 alcohol oxidase peroxisome is impaired in peroxisome biogenesis at 43°C but not at 37°C, the enzyme shows unusual oligomerisation in peroxisomes instead of in the cytosol, overiew 5777 673755 2.5.1.29 geranylgeranyl diphosphate synthase peroxisome isform PaxG 5777 705746 2.3.1.7 carnitine O-acetyltransferase peroxisome isoform Cat2 5777 719875 1.4.3.21 primary-amine oxidase peroxisome isoform CuAO2 5777 724675 1.4.3.21 primary-amine oxidase peroxisome isoform CuAO3 5777 724675 1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+) peroxisome isoform Gdp1p, partly 5777 656246 1.8.1.7 glutathione-disulfide reductase peroxisome isoform GR1 5777 -, 741875 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) peroxisome isoform PGD2 5777 741213 1.1.1.42 isocitrate dehydrogenase (NADP+) peroxisome isoyzme ICD2 5777 656431 1.1.1.42 isocitrate dehydrogenase (NADP+) peroxisome isoyzme IDP3 5777 656233 3.1.2.2 palmitoyl-CoA hydrolase peroxisome isozmes PTE-Ia and PTE-Ib 5777 646197 1.1.1.62 17beta-estradiol 17-dehydrogenase peroxisome isozyme 17beta-HSD4 5777 675982 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+) peroxisome isozyme 17beta-HSD4 5777 675982 2.3.1.9 acetyl-CoA C-acetyltransferase peroxisome isozyme AACT1, its peroxisomal localisation depends on the presence of a C-terminal peroxisomal targeting sequence, PTS1, motif, Ser-Ala-Leu 5777 703818 3.1.2.2 palmitoyl-CoA hydrolase peroxisome isozyme ACH2 5777 646195 3.1.2.20 acyl-CoA hydrolase peroxisome isozyme ACH2 5777 646195 1.5.3.17 non-specific polyamine oxidase peroxisome isozyme AtPAO3 contains a peroxisomal targeting motif at the C terminus 5777 694719 3.1.2.2 palmitoyl-CoA hydrolase peroxisome isozyme family built of ACH1 and ACH2 5777 646196 2.5.1.18 glutathione transferase peroxisome isozyme GSTT 5777 723365 1.1.1.42 isocitrate dehydrogenase (NADP+) peroxisome isozyme IDP3 5777 654367 1.6.5.4 monodehydroascorbate reductase (NADH) peroxisome isozyme MDHAR3 5777 -, 726130 1.3.1.42 12-oxophytodienoate reductase peroxisome isozyme OPR3 5777 656998 3.1.2.2 palmitoyl-CoA hydrolase peroxisome isozyme PTE I 5777 646163 3.1.2.20 acyl-CoA hydrolase peroxisome isozyme PTE I 5777 646163 3.1.2.2 palmitoyl-CoA hydrolase peroxisome isozyme PTE-2, major acyl-CoA thioesterase in peroxisomes 5777 646200 3.1.2.2 palmitoyl-CoA hydrolase peroxisome isozyme PTE-II 5777 646200 3.1.2.20 acyl-CoA hydrolase peroxisome isozyme PTE-II 5777 646200 3.1.2.2 palmitoyl-CoA hydrolase peroxisome isozymes AtACH1 and AtACH2 5777 646196 3.1.2.20 acyl-CoA hydrolase peroxisome isozymes AtACH1 and AtACH2 5777 646196 3.1.2.2 palmitoyl-CoA hydrolase peroxisome isozymes PTE-Ia and PTE-Ib 5777 646197, 651962 3.1.2.20 acyl-CoA hydrolase peroxisome isozymes PTE-Ia and PTE-Ib 5777 646197 6.2.1.30 phenylacetate-CoA ligase peroxisome it is proposed that phenylacetate-CoA ligase and isopenicillin N-acyltransferase form a peroxisomal functional complex 5777 -, 661021 1.4.3.1 D-aspartate oxidase peroxisome its C-terminus has a peroxisome targeting signal 5777 391709 1.7.3.3 factor-independent urate hydroxylase peroxisome limited to large peroxisomes in uninfected cells of root nodules of Glycine max inoculated with Bradyrhizobium japonicum 5777 394138 3.4.21.53 Endopeptidase La peroxisome lon2 5777 682349 1.11.1.6 catalase peroxisome main localization 5777 686756 1.11.1.6 catalase peroxisome mainly in liver and kidney 5777 439797 2.6.1.45 serine-glyoxylate transaminase peroxisome marker enzyme 5777 636691 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+) peroxisome matrix 5777 660941 2.3.3.9 malate synthase peroxisome matrix 5777 -, 638474, 638496, 638503 2.5.1.18 glutathione transferase peroxisome matrix 5777 721532 5.3.3.8 DELTA3-DELTA2-enoyl-CoA isomerase peroxisome matrix 5777 651935 1.17.3.2 xanthine oxidase peroxisome matrix and core of peroxisomes of liver parenchymal cells, xanthine oxidoreductase and xanthine oxidase detected 5777 657487 1.17.1.4 xanthine dehydrogenase peroxisome matrix and core, of parenchymal cells, both oxidase and dehydrogenase activity 5777 657487 2.6.1.60 aromatic-amino-acid-glyoxylate transaminase peroxisome matrix and soluble 5777 637008 2.3.1.137 carnitine O-octanoyltransferase peroxisome matrix of liver peroxisomes 5777 486294 1.5.3.1 sarcosine oxidase (formaldehyde-forming) peroxisome membrane 5777 392398 2.5.1.26 alkylglycerone-phosphate synthase peroxisome membrane 5777 489885 3.5.3.4 allantoicase peroxisome membrane 5777 172141 3.6.4.6 vesicle-fusing ATPase peroxisome membrane, Pex1p possesses two distinct oligomeric forms, a homo-oligomer in the cytosol and a hetero-oligomer on peroxisome membranes, possibly playing distinct functions in peroxisome biogenesis 5777 669490 1.5.3.7 L-pipecolate oxidase peroxisome membrane-associated 5777 392471, 392473, 392477 2.3.1.42 glycerone-phosphate O-acyltransferase peroxisome membrane-bound 5777 486968, 486974 2.7.1.36 mevalonate kinase peroxisome mevalonate kinase is predominantly localized in peroxisomes, but is easily solubilized and released into the cytosol 5777 641453 2.3.1.42 glycerone-phosphate O-acyltransferase peroxisome microperoxisome of brain, intestinal mucosa 5777 486974 5.3.3.8 DELTA3-DELTA2-enoyl-CoA isomerase peroxisome minor intracellular site 5777 3024 1.15.1.1 superoxide dismutase peroxisome Mn-SOD 5777 -, 438184 1.1.1.26 glyoxylate reductase peroxisome NAD+/NADH preferring type 5777 286418, 286419 2.7.1.86 NADH kinase peroxisome NADK3 localizes to the peroxisomal matrix via a novel type 1 peroxisomal targeting signal 5777 706395 1.8.3.1 sulfite oxidase peroxisome nearly exclusively in 5777 660148 4.1.3.4 hydroxymethylglutaryl-CoA lyase peroxisome no activity in lymphoblasts of Zellweger patients 5777 652699 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) peroxisome non-AUG translation initiation generates peroxisomal isoforms of 6-phosphogluconate dehydrogenase 5777 -, 761127 1.15.1.1 superoxide dismutase peroxisome one copper chaperone gene for superoxide dismutase is responsible for the activation of cytosolic, peroxisomal and chloroplast enzyme 5777 676585 1.3.1.42 12-oxophytodienoate reductase peroxisome OPR3 5777 700835 4.2.1.119 enoyl-CoA hydratase 2 peroxisome peroxisomal hydratase 2 together with (3R)-hydroxyacyl-CoA dehydrogenase, and hydratase 1 together with (3S)-hydroxyacyl-CoA dehydrogenase, are present as multifunctional enzymes. When present simultaneously in peroxisomes, beta-oxidation has two stereochemical possibilities 5777 652075 2.3.3.16 citrate synthase (unknown stereospecificity) peroxisome peroxisomal isozyme 5777 488086 3.1.2.2 palmitoyl-CoA hydrolase peroxisome peroxisomal isozyme PTE-I 5777 650787 1.11.1.6 catalase peroxisome peroxisomal matrix 5777 439806 1.5.1.7 saccharopine dehydrogenase (NAD+, L-lysine-forming) peroxisome peroxisomal matrix, the enzyme has a peroxisomal targeting signal type 1 (PTS1) 5777 -, 765801 3.6.4.7 peroxisome-assembly ATPase peroxisome peroxisomal Pex1/Pex6 ATPase complex 5777 735192 2.3.1.9 acetyl-CoA C-acetyltransferase peroxisome peroxisomal thiolase I 5777 487694 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] peroxisome peroxisome matrix 5777 390723 1.1.3.13 alcohol oxidase peroxisome peroxisome targeting requires the peroxisomal targeting signal 1, PTS1 5777 673663 3.6.4.7 peroxisome-assembly ATPase peroxisome peroxisome-specific isoform of Lon protease, peroxisomal proteome analysis 5777 734186 2.7.6.2 thiamine diphosphokinase peroxisome Peroxisomes are devoid of thiamine pyrophosphokinase activity. 5777 672792 3.6.4.7 peroxisome-assembly ATPase peroxisome Pex1p is targeted to peroxisomes in a manner dependent on ATP hydrolysis, while Pex6p targeting requires ATP but not its hydrolysis 5777 733421 3.6.4.7 peroxisome-assembly ATPase peroxisome Pex1p is targeted to peroxisomes in a manner dependent on ATP hydrolysis. Transport of Pex1p and Pex6p is temperature-dependent 5777 721086 3.6.4.6 vesicle-fusing ATPase peroxisome Pex6p is predominantly localized on peroxisomes 5777 669490 3.6.4.7 peroxisome-assembly ATPase peroxisome Pex6p targeting to peroxisomes requires ATP but not its hydrolysis. Transport of Pex1p and Pex6p is temperature-dependent 5777 721086 2.7.4.2 phosphomevalonate kinase peroxisome phosphomevalonate kinase cDNA contains a putative peroxisomal target signal, phosphomevalonate kinase-green fluorescent fusion protein is imported into peroxisomes 5777 645181 2.3.1.42 glycerone-phosphate O-acyltransferase peroxisome predominantly, marker enzyme for peroxisomal membrane 5777 486962 1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase peroxisome presence of S-nitrosoglutathione, S-nitrosoglutathione reductase and nitrated proteins 5777 723896 1.2.1.84 alcohol-forming fatty acyl-CoA reductase peroxisome primarily localized in the microperoxisomes, on the cytosolic surface 5777 719776 6.2.1.30 phenylacetate-CoA ligase peroxisome proliferation rates in strain DS17690, overview 5777 -, 713830 6.2.1.30 phenylacetate-CoA ligase peroxisome proliferation rates in strain NRRL1951, overview 5777 -, 713830 6.2.1.30 phenylacetate-CoA ligase peroxisome proliferation rates in strain Wis54-1255, overview 5777 -, 713830 3.1.1.5 lysophospholipase peroxisome protein contians a putative peroxisomal targeting sequence 5777 704231 1.2.1.8 betaine-aldehyde dehydrogenase peroxisome putative 5777 686072 2.3.1.176 propanoyl-CoA C-acyltransferase peroxisome Scp2 localized to peroxisomes and peroxisomal targeting is necessary for its virulence function 5777 757822 3.3.2.10 soluble epoxide hydrolase peroxisome sEH shows both, peroxisomal and cytosolic localizations in vivo, peroxisomal import occurs when expression levels are high or when the Ser-Lys-Met motif (amino acids 553-555) is accessible 5777 699541 2.3.1.7 carnitine O-acetyltransferase peroxisome sequence contains a N-terminal mitochondrial targeting sequence and a C-terminal peroxisomal targeting sequence and protein is localized to both peroxisomes and mitochondria 5777 719381 1.1.1.184 carbonyl reductase (NADPH) peroxisome sequence contains peroxisomal targeting signal Ser-His-Leu 5777 685454 2.6.1.44 alanine-glyoxylate transaminase peroxisome sequence contains two sites of peroxisomal targeting sequences around amino acids 59-66 and 389-392 5777 685460 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] peroxisome sequence terminates in a consensus type-1 peroxisomal targeting signal. Recombinant PDCR is efficiently transported to the peroxisome lumen 5777 759456 3.6.4.7 peroxisome-assembly ATPase peroxisome structural organization and localization of peroxisomal AAA+ ATPases 5777 733421 3.6.4.7 peroxisome-assembly ATPase peroxisome structural organization and localization of peroxisomal AAA+ ATPases, peroxisomal matrix isozyme 5777 733421 3.6.4.7 peroxisome-assembly ATPase peroxisome structural organization and localization of peroxisomal AAA+ ATPases. Dynamic Pex1p-Pex6p complex assembly at the peroxisomal membrane 5777 733421 3.6.4.7 peroxisome-assembly ATPase peroxisome structural organization and localization of peroxisomal AAA+ ATPases. The peroxisome specific isozyme is Lon2, which carries a PTS1-signal 5777 733421 3.6.4.7 peroxisome-assembly ATPase peroxisome subcellular localization study using recombinant GFP-tagged enzyme expression 5777 682349 2.6.1.14 asparagine-oxo-acid transaminase peroxisome the C-terminal tripeptide Ser-Arg-Ile (residues 399-401) constitute a type 1 peroxisomal targeting sequence (PTS1) 5777 759257 2.6.1.44 alanine-glyoxylate transaminase peroxisome the C-terminal tripeptide Ser-Arg-Ile (residues 399-401) constitute a type 1 peroxisomal targeting sequence (PTS1) 5777 759257 2.6.1.45 serine-glyoxylate transaminase peroxisome the C-terminal tripeptide Ser-Arg-Ile (residues 399-401) constitute a type 1 peroxisomal targeting sequence (PTS1) 5777 759257 2.3.1.65 bile acid-CoA:amino acid N-acyltransferase peroxisome the cytosolic enzyme localization is due to a carboxyterminal non-consensus peroxisomal targeting signal, SQL, since mutation of the SQL to SKL results in BAAT being efficiently imported into peroxisomes 5777 702070 1.1.2.3 L-lactate dehydrogenase (cytochrome) peroxisome the enzyme contains a canonical peroxisomal targeting signal 5777 743494 6.2.1.30 phenylacetate-CoA ligase peroxisome the enzyme contains a peroxisomal targeting signal 1, A-K-L, on its C terminus, indicating its peroxisomal location 5777 -, 727565 1.1.3.15 (S)-2-hydroxy-acid oxidase peroxisome the enzyme contains a peroxisomal targeting signale -ARL 5777 673927 3.3.2.10 soluble epoxide hydrolase peroxisome the enzyme contains an impaired peroxisomal targeting sequence leading to dual localization 5777 663275 1.7.3.3 factor-independent urate hydroxylase peroxisome the enzyme is mainly localized in the peroxisomal matrix of wild-type cells 5777 657736 6.2.1.24 phytanate-CoA ligase peroxisome the enzyme is synthesized on the cytoplasmic surface and is translocated through the membrane for its alpha-oxidation to pristanic acid in the matrix of peroxisomes 5777 703 1.2.1.19 aminobutyraldehyde dehydrogenase peroxisome the isozyme carries the SKL C-terminal peroxisomal targeting signal (PTS-1) 5777 742854 2.3.1.7 carnitine O-acetyltransferase peroxisome the majority of Crat mRNA in mouse is mitochondrial, with only about 1–20% of Crat mRNA being peroxisomal, except for liver, where peroxisomal Crat represents about 38%of total Crat mRNA 5777 686028 3.6.4.6 vesicle-fusing ATPase peroxisome the Walker A1 motif of Pex1p is essential for Pex1p-pex6p interaction and Pex1p targeting to peroxisomes 5777 667439 3.1.2.2 palmitoyl-CoA hydrolase peroxisome thioesterase II 5777 646198 3.1.2.20 acyl-CoA hydrolase peroxisome thioesterase II 5777 646198 2.3.1.16 acetyl-CoA C-acyltransferase peroxisome thiolase A from normal rat liver peroxisomes and thiolase B from livers of clofibrate-treated rats 5777 486435 7.6.2.4 ABC-type fatty-acyl-CoA transporter peroxisome transmembrane protein anchored in the peroxisomal membrane by its amino-terminal hydrophobic domain, possibly forming a channel, the ATP-binding domain is exposed to the cytosol 5777 210403 5.3.3.8 DELTA3-DELTA2-enoyl-CoA isomerase peroxisome trifunctional enzyme which exhibits the activities of EC5.3.3.8, EC 4.2.1.17 and EC 1.1.1.35 5777 3015 2.5.1.26 alkylglycerone-phosphate synthase peroxisome type-1 peroxisomal targeting signal 5777 489891, 489892 2.5.1.26 alkylglycerone-phosphate synthase peroxisome type-2 peroxisomal targeting signal 5777 489892 2.5.1.26 alkylglycerone-phosphate synthase peroxisome Uniprot 5777 737578 7.6.2.4 ABC-type fatty-acyl-CoA transporter peroxisome upon expression in Saccharomyces cerevisiae, CTS is correctly targeted to yeast peroxisomes, and assembled into the membrane with its nucleotide binding domains in the cytosol 5777 719885 7.6.2.4 ABC-type fatty-acyl-CoA transporter peroxisome when both the N-terminal 80-segment and the following TM1-TM2 region are present, the fusion protein locates exclusively to the peroxisome 5777 712319 2.6.1.44 alanine-glyoxylate transaminase peroxisome wild type enzyme 5777 676835 2.7.4.2 phosphomevalonate kinase peroxisome wild-type PMVK 5777 760138