3.1.3.6 cell surface the 3'-nucleotidase activity is exclusively located on the Leishmania amazonensis external surface 9986 714930 3.1.3.6 endoplasmic reticulum the N-terminal signal peptide targets the enzyme into the endoplasmic reticulum 5783 651998 3.1.3.6 membrane - 16020 714930 3.1.3.6 membrane cell surface membrane-anchored protein, the C-terminal domain of the enzyme functions to anchor this protein into the parasite cell surface membrane 16020 651998 3.1.3.6 membrane outer membrane 16020 -, 690524 3.1.3.6 membrane surface membrane 16020 651547 3.1.3.6 membrane surface membrane anchored enzyme 16020 -, 653205 3.1.3.6 plasma membrane - 5886 -, 690754, 95087, 95088 3.1.3.6 plasma membrane 55% on the outer surface and the remaining activity presumably on the inside of the plasma membrane 5886 95089 3.1.3.6 plasma membrane enzyme oriented outward 5886 95086 3.1.3.6 plasma membrane starvation for purines and/or phosphates leads to enhanced surface expression 5886 95094 3.1.3.6 plasma membrane surface membrane associated 5886 95091