2.5.1.22 additional information - additional information ratio of kcat/Km value of wild-type is 40000 for substrate spermidine, and 71000000 for S-adenosyl-L-methioninamine, respectively 687717 2.5.1.22 0.0001 - S-adenosylmethioninamine - 489873 2.5.1.22 0.0005 - S-adenosyl 3-(methylthio)propylamine wild type enzyme, at pH 7.5 and 37°C 739393 2.5.1.22 0.00054 - 7,7-Difluorospermidine - 489869 2.5.1.22 0.0006 - S-adenosylmethioninamine - 489863, 489864, 489875 2.5.1.22 0.0009 - S-adenosyl 3-(methylthio)propylamine mutant enzyme S165D/L175E/T178H/C206R, at pH 7.5 and 37°C 739393 2.5.1.22 0.001 - S-adenosylmethioninamine - 489868 2.5.1.22 0.0011 - 7-Monofluorospermidine - 489869 2.5.1.22 0.005 - S-adenosylmethioninamine - 489862 2.5.1.22 0.006 - spermidine - 489863, 489864, 489873 2.5.1.22 0.02 - spermidine - 489861 2.5.1.22 0.07 - spermidine - 489862 2.5.1.22 0.084 0.088 spermidine - 489869 2.5.1.22 0.093 - 6-monofluorospermidine - 489869 2.5.1.22 0.2 - spermidine placenta 489868 2.5.1.22 0.458 - 6,6-difluorospermidine - 489869 2.5.1.22 0.6 - spermidine mutant enzyme S165D/L175E/T178H/C206R, at pH 7.5 and 37°C 739393 2.5.1.22 0.8 - spermidine wild type enzyme, at pH 7.5 and 37°C 739393