2.4.2.9 additional information - additional information - 658679 2.4.2.9 additional information - additional information allosteric transition, structural and kinetic studies, overview 705159 2.4.2.9 additional information - additional information kinetics 638369 2.4.2.9 additional information - additional information Km-value for 5-phosphoribose 1-diphosphate of the mutant P131D is very low and difficult to determine 638372 2.4.2.9 additional information - additional information Km-values, recombinant mutant enzymes 638374 2.4.2.9 0.0004 - Uracil - 638360 2.4.2.9 0.00063 - Uracil recombinant wild-type 638372 2.4.2.9 0.001 - Uracil pH 6.1, without GTP 678368 2.4.2.9 0.002 - Uracil - 638370 2.4.2.9 0.002 - Uracil pH 8.0, without GTP 678368 2.4.2.9 0.0035 - Uracil recombinant enzyme 638367 2.4.2.9 0.004 - Uracil pH 6.1, presence of 1 mM GTP 678368 2.4.2.9 0.0042 - Uracil - 638363 2.4.2.9 0.005 - Uracil pH 8.0, presence of 1 mM GTP 678368 2.4.2.9 0.0064 - 5-fluorouracil at pH 7.5 and 25°C 736431 2.4.2.9 0.0069 - 5-phospho-alpha-D-ribose 1-diphosphate - 638360 2.4.2.9 0.007 - Uracil - 638362 2.4.2.9 0.0071 - 4-thiouracil at pH 7.5 and 25°C 736431 2.4.2.9 0.0077 - Uracil - 638364 2.4.2.9 0.0124 - Uracil at pH 7.5 and 25°C 737104 2.4.2.9 0.016 - 5-phospho-alpha-D-ribose 1-diphosphate pH 8.0, without GTP 678368 2.4.2.9 0.0204 - Uracil at pH 7.5 and 25°C 736431 2.4.2.9 0.021 - Uracil - 638365 2.4.2.9 0.024 - Uracil - 638368 2.4.2.9 0.026 - 5-phospho-alpha-D-ribose 1-diphosphate - 638365 2.4.2.9 0.037 - 5-phospho-alpha-D-ribose 1-diphosphate recombinant wild-type, with GTP 638374 2.4.2.9 0.044 - 5-phospho-alpha-D-ribose 1-diphosphate - 638358 2.4.2.9 0.049 - 5-phospho-alpha-D-ribose 1-diphosphate pH 8.0, presence of 1 mM GTP 678368 2.4.2.9 0.05 - 5-phospho-alpha-D-ribose 1-diphosphate - 638370 2.4.2.9 0.06 - Uracil recombinant mutant P131D 638372 2.4.2.9 0.066 - 5-phospho-alpha-D-ribose 1-diphosphate - 638363 2.4.2.9 0.068 - 5-phospho-alpha-D-ribose 1-diphosphate - 638371 2.4.2.9 0.0705 - Uracil - 638366 2.4.2.9 0.073 - 5-phospho-alpha-D-ribose 1-diphosphate recombinant wild-type 638372 2.4.2.9 0.079 - 5-phospho-alpha-D-ribose 1-diphosphate pH 6.1, without GTP 678368 2.4.2.9 0.0993 - 5-phospho-alpha-D-ribose 1-diphosphate with uracil as cosubstrate, at pH 7.5 and 25°C 736431 2.4.2.9 0.115 - 5-phospho-alpha-D-ribose 1-diphosphate pH 6.1, presence of 1 mM GTP 678368 2.4.2.9 0.13 - UMP - 638371 2.4.2.9 0.159 - Uracil - 638371 2.4.2.9 0.186 - 5-phospho-alpha-D-ribose 1-diphosphate - 638366 2.4.2.9 0.2 - 5-phospho-alpha-D-ribose 1-diphosphate - 638368 2.4.2.9 0.216 - 5-phospho-alpha-D-ribose 1-diphosphate recombinant wild-type, without GTP 638374 2.4.2.9 0.243 - 5-phospho-alpha-D-ribose 1-diphosphate recombinant enzyme 638367 2.4.2.9 0.3 - 5-phospho-alpha-D-ribose 1-diphosphate - 638362 2.4.2.9 0.67 - 2-Thiouracil - 638364 2.4.2.9 1 - diphosphate - 638371