2.5.1.16	1,3-diaminopropane	34% inhibition	721	
2.5.1.16	1,3-diaminopropane	96% inhibition at 0.01 mM and 100% inhibition at 0.1 mM	721	
2.5.1.16	1,5-Diaminopentane	weak, competitive	3172	
2.5.1.16	1,6-diaminohexane	23% inhibition	1524	
2.5.1.16	1-Aminooxy-3-aminopropane	brain enzyme, specific, no inhibition of spermine synthase, reversible, competitive with 1,4-diaminobutane	29267	
2.5.1.16	1-Aminooxy-3-aminopropane	poor inhibition	29267	
2.5.1.16	1H-benzimidazol-5-yl(4-[(2Z)-3-phenylprop-2-en-1-yl]piperazin-1-yl)methanone	identified by a five-step structure-based virtual screening procedure as a binder to spermidine synthase active site. Binds reversibly to the active site and partially competes with binding of methylthioadenosine	142992	
2.5.1.16	2-mercaptoethylamine	competitive with 1,4-diaminobutane, reversible, its removal restores the enzyme activity, the amino group is necessary to inhibit the enzyme	6431	
2.5.1.16	2-mercaptoethylamine	poor inhibition	6431	
2.5.1.16	2-phenyl-1,2-thiazol-3(2H)-one	-	212864