2.3.1.108 Ca2+ - 15 2.3.1.108 Ca2+ at 1 mM, almost complete inhibition; inhibition is due to the binding of calcium to the tubulin dimer rather than to the enzyme itself 15 2.3.1.108 CoA competitive inhibitor 18 2.3.1.108 Colchicine at 0.001 mM is inhibitory to microtubule acetylation 3334 2.3.1.108 additional information analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview 2