6.3.1.8 (2-[[([2-[(4-amino-4-carboxybutanoyl)amino]propanoyl]amino)methyl](hydroxy)phosphoryl]ethyl)(hydroxy)dioxophosphate(1-) inhibits the reaction in the presence of spermidine 135155 6.3.1.8 4-[(14-ammonio-5-hydroxy-1-methyl-5-oxido-2-oxo-6-oxa-3,10-diaza-5-phosphatetradec-1-yl)amino]-1-carboxy-4-oxobutan-1-aminium - 61963 6.3.1.8 4-[[2-([[[4-[(4-ammoniobutyl)amino]butyl](hydroxy)phosphoryl]methyl]amino)-1-methyl-2-oxoethyl]amino]-1-carboxy-4-oxobutan-1-aminium - 61962 6.3.1.8 buthionine sulfoximine - 2076 6.3.1.8 gamma-Aminobutyryl-L-Ala-Gly 5 mM, 10% inhibition 93433 6.3.1.8 gamma-glutamyl-N-[[(3-aminopropoxy)(2-phosphonoethyl)phosphoryl]methyl]alaninamide - 135154 6.3.1.8 gamma-L-Glu-D-Phe-Gly 5 mM, 10% inhibition 93452 6.3.1.8 gamma-L-Glu-L-Leu 5 mM, 10% inhibition 93462 6.3.1.8 gamma-L-Glu-L-Leu-Gly 5 mM, 58% inhibition 93463 6.3.1.8 gamma-L-Glu-L-leu-L-Ala 5 mM, 95% inhibition 93464 6.3.1.8 gamma-L-Glu-L-Phe-Gly 5 mM, 73% inhibition 93466 6.3.1.8 gamma-L-Glu-L-Ser-Gly 5 mM, 50% inhibition 44148 6.3.1.8 gamma-L-Glu-L-Val 5 mM, 10% inhibition 93469 6.3.1.8 gamma-L-Glu-L-Val-L-Ala 5 mM, 58% inhibition 93470 6.3.1.8 gamma-L-glutamyl-L-cysteinyl-diaminopropionic acid - 33878 6.3.1.8 Glutaryl-L-Val-Gly 5 mM, 10% inhibition 93508 6.3.1.8 Hydrogen O-[3-[N-(4-Aminobutyl)amino]propyl][[(gamma-glutamylalanyl)amino]methyl]phosphonate - 96614 6.3.1.8 L-beta-Asp-L-Leu-Gly 5 mM, 42% inhibition 93803 6.3.1.8 L-beta-Asp-L-Val-Gly 5 mM, 15% inhibition 93804 6.3.1.8 L-Cys-Gly 5 mM, 20% inhibition 20334 6.3.1.8 megazol - 57907 6.3.1.8 Melarsen oxide - 3825 6.3.1.8 additional information a series of glutathione analogs where the glycine moiety is substituted for other amino acids can act as inhibitors 2 6.3.1.8 additional information the enzyme mediates resistance to H2O2 and organic hyperoxids, and to trypanocidic drugs 2 6.3.1.8 additional information H2O2 leads to inhibition of the amidase activity, while the glutathionylspermidine synthase activity is almost unaffected 2 6.3.1.8 additional information design, synthesis, and biochemical evaluation of phosphonate and phosphonamidate analogs of glutathionylspermidine as inhibitors 2 6.3.1.8 N1-glutathionylspermidine analogs selective inhibitors against EC 6.3.1.8 and EC 3.5.1.78 activities provide evidence of interdomain communication in the bifunctional enzyme 96906 6.3.1.8 nifurtimox - 3221 6.3.1.8 Non-polyamine-containing phosphoamidate - 98513 6.3.1.8 Pentamidine - 2216 6.3.1.8 Phosphinate behaves as a slow-binding bisubstrate inhibitor, competitive with respect to GSH and spermidine 20466 6.3.1.8 phosphinate analogue of glutathionylspermidine slow tight-binding inhibition 72000 6.3.1.8 phosphonate acts as a a simple ground state analogue of glutathione 3397 6.3.1.8 phosphonate analogue of glutathionylspermidine classical, linear competitive inhibition with respect to GSH 72001 6.3.1.8 Polyamine-containing phosphapeptides potent and selective 99627 6.3.1.8 reduced trypanothione - 12887 6.3.1.8 triostam - 32741