3.6.5.6	Br-	-	332	
3.6.5.6	citral dimethyl acetal	CDA, impairs the GTPase activity of gamma-tubulin	247644	
3.6.5.6	Cl-	enhancement of tubulin polymerization by Cl--induced blockade of intrinsic GTPase. GTPase activity of tubulin is lower (2/3-fold) in Cl--containing solutions than that in Cl--free solutions containing Br- or NO3-	141	
3.6.5.6	Colchicine	a small molecule inhibitor that binds to tubulin dimers rendering them unable to incorporate into filaments. It does not destabilize actively, but rather inhibit repolymerization after regular depolymerization	3334	
3.6.5.6	curcumin	-	696	
3.6.5.6	diethyldicarbonate	inhibits GTP hydrolysis, but not the assembly reaction	310	
3.6.5.6	EDTA	strong inhibition at 2 mM	21	
3.6.5.6	GDP	-	53	
3.6.5.6	GTP	inhibitory effect produced at concentrations above 3 mM, above 5 mM leads to depolymerization of microtubules	37	
3.6.5.6	guanosine 5'-(gamma-fluorotriphosphate)	reversible competitive dead-end inhibitor	106232	
3.6.5.6	guanosine 5'-(gamma-thiotriphosphate)	inhibits both tubulin polymerization and GTP hydrolysis	106233	
3.6.5.6	additional information	the phosphorylated protein shows hardly any activity	2	
3.6.5.6	additional information	a class of destabilizers consists of the microtubule-severing enzymes from the ATPases associated with various cellular activities (AAA+) family of ATP-enzymes. GTP-driven microtubule dynamics are coupled to ATP-driven destabilization by severing enzymes, examples and mechanism, detailed overview	2	
3.6.5.6	N-ethylmaleimide	inhibits GTP hydrolysis, but not the assembly reaction	49	
3.6.5.6	N-terminal part of stathimin like-domains	-	144085	
3.6.5.6	NO3-	-	673	
3.6.5.6	rotenone	rotenone inhibits both the assembly and the GTP hydrolysis rate of microtubules in vitro	777	
3.6.5.6	tubulin	unassembled tubulin denatures relatively easily, and the denatured tubulin can inhibit the assembly itself	3869	
3.6.5.6	vinblastine	-	3132	
3.6.5.6	vinblastine	a small molecule inhibitor that binds to tubulin dimers rendering them unable to incorporate into filaments. It does not destabilize actively, but rather inhibit repolymerization after regular depolymerization	3132