3.2.1.130 (3R,4R,5R)-3-(alpha-D-glucopyranosyloxy)-4-hydroxy-5-(hydroxymethyl)piperidine - 201145 3.2.1.130 alpha-glucopyranosyl-(1->3)-deoxymannojirimycin - 201144 3.2.1.130 alpha-Man-1,3-noeuromycin potent inhibitor 232770 3.2.1.130 alpha-mannopyranosyl-(1->3)-isofagomine - 201142 3.2.1.130 alpha-mannopyranosyl-1->3-isofagomine - 201143 3.2.1.130 alpha-mannosyl-1,3-(2-aminodeoxymannojirimycin) the inhibitor binds like other iminosugar inhibitors. The poor inhibition shown by this compound is not a result of a failure to achieve the expected interaction with the general base, but rather the reduction in basicity of the endocyclic nitrogen caused by introduction of a vicinal, protonated amine at C2 232768 3.2.1.130 alpha-mannosyl-1,3-mannoimidazole the inhibitor binds with the imidazole headgroup distorted downwards, a result of an unfavourable interaction with a conserved active site tyrosine 232769 3.2.1.130 Glucosyl alpha1-3(1-deoxy)mannojirimycin - 93502 3.2.1.130 additional information not impaired by 1-deoxynojirimycin, no inhibition by EDTA 2 3.2.1.130 additional information unaffected by glucosidase inhibitors 2 3.2.1.130 additional information brefeldin A prevents the maturation of endomannosidase 2