1.14.14.127 1-(2-methylpropyl)-5-[4-([4-[3-(trifluoromethyl)-3H-diaziren-3-yl]benzyl]oxy)phenyl]-1H-imidazole bifunctional compound, inhibits juvenile hormone III synthesis by intact glands as well as methyl farnesoate epoxidation by gland homogenates. Using the compound, a radiolabeled and photoactivatable diazirine or benzophenone group can be introduced to label the hydrophobic substrate binding site of the enzyme 199390 1.14.14.127 5-(2-(benzyloxy)phenyl)-1-(3,7-dimethyloct-6-en-1-yl)-1H-imidazole - 201135 1.14.14.127 5-(3-[[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy]phenyl)-1-(2-methylpropyl)-1H-imidazole - 196519 1.14.14.127 5-[3-(benzyloxy)phenyl]-1-(2-methylpropyl)-1H-imidazole - 196518 1.14.14.127 carbon monoxide/oxygen atmosphere half-maximal inhibition at a CO/O ratio of 4.0. Inhibition is reversed by white-light irradiation 201134 1.14.14.127 cytochrome c inhibition by oxidized cytochrome c, 20 microM, 52.4% residual activity 84 1.14.14.127 methyl (2E,6E)-3,7-dimethyl-8-(3,4-methylenedioxyphenoxy)-octadienoate inhibits juvenile hormone biosynthesis in vitro by spontaneously active glands, presumably by direct inhibition of the epoxidase, and also inhibits the production of total methyl ester 201136 1.14.14.127 additional information inhibition 1,5-disubstituted imidazoles 2 1.14.14.127 NADP+ 2 mM, 57.2% residual activity 10 1.14.14.127 [4-([4-[1-(2-methylpropyl)-1H-imidazol-5-yl]phenoxy]methyl)phenyl](phenyl)methanone bifunctional compound, inhibits juvenile hormone III synthesis by intact glands as well as methyl farnesoate epoxidation by gland homogenates. Using the compound, a radiolabeled and photoactivatable diazirine or benzophenone group can be introduced to label the hydrophobic substrate binding site of the enzyme 199391