2.6.1.45 additional information not inhibited with or without NH4+ by oxalate, formate, acetaldehyde, pyruvate, hydroxypyruvate, 2-oxoglutarate 2 2.6.1.45 additional information not inhibited by NaBH4, 3-chloro-D-alanine, 1,10-phenanthroline, 2,2'-dipyridyl, 8-hydroxyquinoline, EDTA, iodoacetate, FeCl3, AlCl3, CdCl2, CoCl2, NiCl2, CaCl2, NaN3, ZnCl2, PbCl2, LiCl, CuCl2, BaCl2, ascorbate, cysteamine, N-ethylmaleimide 2 2.6.1.45 additional information not inhibited by 5,5'-dithio-bis(2-nitrobenzoate) 2 2.6.1.45 pyruvate competitive vs. glyoxylate 31 2.6.1.45 2-oxoglutarate 2-oxoglutarate at a concentration above 12.5 mM inhibits enzyme SgaBath in the serine-2-oxoglutarate aminotransferase (SKAT) reaction, but has no effect on the serine-glyoxylate aminotranferase (SGAT) reaction, substrate inhibition 34 2.6.1.45 2-oxoglutarate 2-oxoglutarate at a concentration above 12.5 mM inhibits enzyme Sga20Z in the serine-2-oxoglutarate aminotransferase (SKAT) reaction, but has no effect on the serine-glyoxylate aminotranferase (SGAT) reaction, substrate inhibition 34 2.6.1.45 p-chloromercuribenzoate 1 mM, 37% inhibition 43 2.6.1.45 p-chloromercuribenzoate - 43 2.6.1.45 N-ethylmaleimide 1 mM, 41% inhibition 49 2.6.1.45 N-ethylmaleimide - 49 2.6.1.45 N-ethylmaleimide weak, but significant inhibition 49 2.6.1.45 NH4+ reversible inhibition 54 2.6.1.45 NH4+ - 54 2.6.1.45 iodoacetamide - 67 2.6.1.45 glycine competitive vs. L-serine 72 2.6.1.45 hydroxylamine 0.01 mM, 98% inhibition of serine-glyoxylate transamination 85 2.6.1.45 hydroxylamine 0.01 mM, 85% inhibition of glycin-hydroxypyruvate transamination 85 2.6.1.45 hydroxylamine 0.1 mM, 97% inhibition, 85% inhibition in the presence of 0.1 mM pyridoxal phosphate 85 2.6.1.45 hydroxylamine 0.002 mM, 92% inhibition, serine, L-alanine and glycine protect 85 2.6.1.45 hydroxylamine - 85 2.6.1.45 hydroxylamine 0.1 mM, 70% inhibition 85 2.6.1.45 L-serine competitive vs. asparagine 95 2.6.1.45 p-hydroxymercuribenzoate - 98 2.6.1.45 p-hydroxymercuribenzoate weak but significant inhibition 98 2.6.1.45 p-hydroxymercuribenzoate the 24.1% decrease in enzyme activity achieved using 1.0 mM inhibitor might be considered to be unspecific 98 2.6.1.45 glyoxylate competitive vs. pyruvate 101 2.6.1.45 glyoxylate irreversible inhibition only in the presence of NH4+, inactivation in the absence of amino acid substrates 101 2.6.1.45 glyoxylate amino acid substrates partially protect 101 2.6.1.45 glyoxylate presence of D-serine protects against inhibition 101 2.6.1.45 glyoxylate inhibited by glyoxylate above 6 mM 101 2.6.1.45 L-alanine competitive vs. L-serine 103 2.6.1.45 HgCl2 strong inhibition 110 2.6.1.45 formaldehyde glyoxylate protects 130 2.6.1.45 KCN weak inhibition 161 2.6.1.45 oxalate competitive vs. 2-oxomalonate, uncompetitive vs. L-serine 185 2.6.1.45 MgCl2 weak inhibition 196 2.6.1.45 NaF weak inhibition 235 2.6.1.45 L-asparagine competitive vs. serine 266 2.6.1.45 NH4Cl 0.1 mM, 42% inhibition, 10 mM, complete inhibition 329 2.6.1.45 NH4Cl glycine-hydroxypyruvate transamination is only weakly inhibited 329 2.6.1.45 NH4Cl competitive vs. L-serine 329 2.6.1.45 AgNO3 strong inhibition 360 2.6.1.45 Semicarbazide - 382 2.6.1.45 phenylhydrazine weak inhibition 398 2.6.1.45 (NH4)2SO4 0.05 mM, 45% inhibition, 5 mM, complete inhibition 399 2.6.1.45 D-serine competitive inhibition 481 2.6.1.45 D-serine competitive inhibition with L-serine 481 2.6.1.45 Aminooxyacetate 1 mM, complete inhibition 1374 2.6.1.45 Aminooxyacetate competitive inhibition 1374 2.6.1.45 Aminooxyacetate reacts with the carbonyl group of pyridoxal phosphate, 88% inhibition at 0.01 mM 1374 2.6.1.45 beta-chloro-L-alanine reacts with the carbonyl group of pyridoxal phosphate. 53.9% inhibition at 1 mM 1641 2.6.1.45 Isonicotinic acid hydrazide 0.1 mM, 20% inhibition 2409 2.6.1.45 Penicillamine weak inhibition 2496 2.6.1.45 cycloserine weak inhibition 2837 2.6.1.45 3-chloro-L-alanine - 3967 2.6.1.45 beta-chloroalanine competitive vs. L-alanine, uncompetitive vs. 2-oxomalonate 5134 2.6.1.45 ammonium acetate 0.1 mM, 42% inhibition, 10 mM, complete inhibition 9097 2.6.1.45 SH-group inhibitor - 114430