3.4.21.117 kallikrein 5 activates proform of kallikrein 7 665944 3.4.21.117 additional information estrogen and glucocorticoids cause up-regulation of gene expression 647332, 647349 3.4.21.117 additional information KLK7 is activated by proteolytic cleavage through meprin alpha and beta, and through trypsin, overview. Cleavage by meprins enhances activation of LKL7 through trypsin 707623 3.4.21.117 plasmin - 717274 3.4.21.117 Thermolysin - 717274