2.7.11.30	actividin	activates Smad2 phosphorylation via type I receptor kinases	663984	
2.7.11.30	actividin	binds and activates the type I receptor ALK7	664721	
2.7.11.30	actividin	TGF-beta receptor I and ALK7 possess an actividin receptor-binding domain	664282	
2.7.11.30	actividin A	required for activity in a complex formed with ALK4 and ActRIIB or ActRII, identification of the functional binding site	665487	
2.7.11.30	actividin B	required for activity in a complex formed with ALK4 and ActRIIB or ActRII, identification of the functional binding site	665487	
2.7.11.30	ALK5	is important for ALK1/TGF-beta signaling	666312	
2.7.11.30	growth differentiation factor-9	i.e. GDF-9, interacts with bone morphogenetic protein type II receptor, and activates type I actividin receptor-like kinase 5, ALK5, GDF-9 belongs to the TGF-beta family, no stimulation of receptors ALK1, ALK2, ALK3, and ALKA6 by GDF-9	666359	
2.7.11.30	additional information	increased D-glucose and palmitate concentrations increase the ALK7 enzyme expression in INS-1 cells	664721	
2.7.11.30	nodal	-	664282	
2.7.11.30	SARA protein	i.e. Smad anchor for receptor activation protein, binding site for co-modulator Smad4, modulates self-association of partially phosphorylated Smad2 preventing premature release of monophosphorylated substrate, interaction with Smad2 via the Smad2 MH2 domain	664036