1.1.1.284	formaldehyde	in the presence of NAD+ and initial absence of NADH, ADH3-mediated S-nitrosoglutathione reduction is triggered by the presence of formaldehyde	696092	
1.1.1.284	glutathione	dependent on	742700	
1.1.1.284	additional information	formaldehyde induces the enzyme expression	686818	
1.1.1.284	additional information	the GSNOR1/HOT5/PAR2 protein level, other than its steady-state mRNA level, is induced by paraquat	703110	
1.1.1.284	NADH	increasing intracellular NADH levels are likely to trigger S-nitrosoglutathione reduction	697214	
1.1.1.284	pyrazole	no effect	287866	
1.1.1.284	pyrazole	stimulates	287866	
1.1.1.284	S-nitrosoglutathione	i.e. GSNO, kinetic activation of GSNOR by its substrate S-nitrosoglutathione (GSNO). Enzyme GSNOR kinetic analysis data results in nonhyperbolic behavior that was successfully accommodated by the Hill-Langmuir equation with a Hill coex0ecient of +1.75, indicating that the substrate, GSNO, is acting as a positive allosteric affector. GSNO activates GSNOR by binding to an allosteric site comprised of the residues Asn185, Lys188, Gly321, and Lys323	762616