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TaxTree of Organism Trypanosoma brucei
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EC NUMBER 
COMMENTARY 
-
preliminary BRENDA-supplied EC number
preliminary BRENDA-supplied EC number
preliminary BRENDA-supplied EC number
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
(3R)-N-[(2S)-1-hydroxy-6-[(3R)-3-isocyanobutanamido]hexan-2-yl]-3-isocyanobutanamide biosynthesis
-
-
PWY-8320
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)
-
-
PWY-7726
(5R)-carbapenem carboxylate biosynthesis
(5Z)-dodecenoate biosynthesis I
-
-
PWY0-862
(5Z)-dodecenoate biosynthesis II
-
-
PWY-7858
(5Z)-icosenoate biosynthesis
-
-
PWY-5361
(9Z)-tricosene biosynthesis
-
-
PWY-7035
(aminomethyl)phosphonate degradation
-
-
PWY-7805
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)
-
-
PWY-7216
(R)-cysteate degradation
-
-
PWY-6642
(S)-lactate fermentation to propanoate, acetate and hydrogen
-
-
PWY-8086
(S)-propane-1,2-diol degradation
-
-
PWY-7013
(S)-reticuline biosynthesis I
-
-
PWY-3581
1,2-dichloroethane degradation
-
-
12DICHLORETHDEG-PWY
1,3-propanediol biosynthesis (engineered)
-
-
PWY-7385
1,5-anhydrofructose degradation
-
-
PWY-6992
1-butanol autotrophic biosynthesis (engineered)
-
-
PWY-6886
10-cis-heptadecenoyl-CoA degradation (yeast)
-
-
PWY-7337
10-trans-heptadecenoyl-CoA degradation (MFE-dependent, yeast)
-
-
PWY-7339
10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)
-
-
PWY-7338
1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)
-
-
PWY-6361
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
-
-
PWY-6362
1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)
-
-
PWY-4661
1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)
-
-
PWY-6372
1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)
-
-
PWY-6554
2'-deoxymugineic acid phytosiderophore biosynthesis
-
-
PWY-5912
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA
-
-
PWY-5652
2-aminoethylphosphonate biosynthesis
-
-
PWY-6839
2-arachidonoylglycerol biosynthesis
-
-
PWY-8052
2-deoxy-D-glucose 6-phosphate degradation
-
-
PWY-8121
2-methyl-branched fatty acid beta-oxidation
-
-
PWY-8181
2-methylcitrate cycle I
-
-
PWY0-42
2-methylcitrate cycle II
-
-
PWY-5747
2-methylpropene degradation
-
-
PWY-7778
2-oxoglutarate decarboxylation to succinyl-CoA
-
-
PWY-5084
2-oxoisovalerate decarboxylation to isobutanoyl-CoA
-
-
PWY-5046
24-epi-campesterol, fucosterol, and clionasterol biosynthesis (diatoms)
-
-
PWY-8238
3,6-anhydro-alpha-L-galactopyranose degradation
-
-
PWY-7562
3-(4-hydroxyphenyl)pyruvate biosynthesis
-
-
PWY-5886
3-hydroxy-4-methyl-anthranilate biosynthesis I
-
-
PWY-7717
3-hydroxy-4-methyl-anthranilate biosynthesis II
-
-
PWY-7765
3-hydroxypropanoate cycle
-
-
PWY-5743
3-hydroxypropanoate/4-hydroxybutanate cycle
-
-
PWY-5789
3-hydroxyquinaldate biosynthesis
-
-
PWY-7733
3-methyl-branched fatty acid alpha-oxidation
-
-
PWY66-387
3-methylbutanol biosynthesis (engineered)
-
-
PWY-6871
3-phenylpropanoate degradation
-
-
P281-PWY
3-phosphoinositide biosynthesis
-
-
PWY-6352
3-phosphoinositide degradation
-
-
PWY-6368
4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis II
-
-
PWY-7282
4-aminobutanoate degradation V
-
-
PWY-5022
4-deoxy-L-threo-hex-4-enopyranuronate degradation
-
-
PWY-6507
4-hydroxy-2(1H)-quinolone biosynthesis
-
-
PWY-6661
4-hydroxy-2-nonenal detoxification
-
-
PWY-7112
4-hydroxybenzoate biosynthesis I (eukaryotes)
-
-
PWY-5754
4-hydroxybenzoate biosynthesis III (plants)
-
-
PWY-6435
4-oxopentanoate degradation
-
-
PWY-7948
5'-deoxyadenosine degradation I
-
-
PWY-8130
5'-deoxyadenosine degradation II
-
-
PWY-8131
5,6-dimethylbenzimidazole biosynthesis I (aerobic)
-
-
PWY-5523
5-oxo-L-proline metabolism
-
-
PWY-7942
6-gingerol analog biosynthesis (engineered)
-
-
PWY-6920
7-(3-amino-3-carboxypropyl)-wyosine biosynthesis
-
-
PWY-7286
8-amino-7-oxononanoate biosynthesis I
-
-
PWY-6519
8-amino-7-oxononanoate biosynthesis IV
-
-
PWY-8203
9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)
-
-
PWY-7340
ABH and Lewis epitopes biosynthesis from type 1 precursor disaccharide
-
-
PWY-7832
ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide
-
-
PWY-7831
Ac/N-end rule pathway
-
-
PWY-7800
acetaldehyde biosynthesis I
-
-
PWY-6333
acetaldehyde biosynthesis II
-
-
PWY-6330
acetate and ATP formation from acetyl-CoA I
-
-
PWY0-1312
acetate and ATP formation from acetyl-CoA III
-
-
PWY-8328
acetate conversion to acetyl-CoA
-
-
PWY0-1313
acetate formation from acetyl-CoA (succinate)
-
-
PWY-5536
acetone degradation I (to methylglyoxal)
-
-
PWY-5451
acetone degradation III (to propane-1,2-diol)
-
-
PWY-7466
acetyl-CoA fermentation to butanoate
-
-
PWY-5676
acetylene degradation (anaerobic)
-
-
P161-PWY
acridone alkaloid biosynthesis
-
-
PWY-5958
acrylonitrile degradation I
-
-
PWY-7308
adenine and adenosine salvage I
-
-
P121-PWY
adenine and adenosine salvage II
-
-
PWY-6605
adenine and adenosine salvage III
-
-
PWY-6609
adenine and adenosine salvage V
-
-
PWY-6611
adenine and adenosine salvage VI
-
-
PWY-6619
adenine salvage
-
-
PWY-6610
adenosine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7227
adenosine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7220
adenosine nucleotides degradation I
-
-
PWY-6596
adenosine nucleotides degradation II
-
-
SALVADEHYPOX-PWY
adenosine ribonucleotides de novo biosynthesis
-
-
PWY-7219
adipate biosynthesis
-
-
PWY-8347
adipate degradation
adlupulone and adhumulone biosynthesis
-
-
PWY-7857
aerobic respiration I (cytochrome c)
-
-
PWY-3781
aerobic respiration II (cytochrome c) (yeast)
-
-
PWY-7279
aerobic respiration III (alternative oxidase pathway)
-
-
PWY-4302
agarose degradation
-
-
PWY-6816
alanine racemization
-
-
PWY-8072
alkane biosynthesis I
-
-
PWY-7032
alkane biosynthesis II
-
-
PWY-7033
all-trans-farnesol biosynthesis
-
-
PWY-6859
alliin metabolism
-
-
PWY-5706
alpha-linolenate metabolites biosynthesis
-
-
PWY-8398
Amaryllidacea alkaloids biosynthesis
-
-
PWY-7826
aminopropanol phosphate biosynthesis II
-
-
PWY-7378
aminopropylcadaverine biosynthesis
-
-
PWY0-1303
ammonia assimilation cycle I
-
-
PWY-6963
ammonia assimilation cycle II
-
-
PWY-6964
ammonia assimilation cycle III
-
-
AMMASSIM-PWY
ammonia oxidation II (anaerobic)
-
-
P303-PWY
amygdalin and prunasin degradation
-
-
PWY-6011
anaerobic energy metabolism (invertebrates, cytosol)
-
-
PWY-7383
anaerobic energy metabolism (invertebrates, mitochondrial)
-
-
PWY-7384
anandamide biosynthesis I
-
-
PWY-8051
anandamide biosynthesis II
-
-
PWY-8053
androstenedione degradation I (aerobic)
-
-
PWY-6944
androstenedione degradation II (anaerobic)
-
-
PWY-8152
ansatrienin biosynthesis
-
-
PWY-8040
anteiso-branched-chain fatty acid biosynthesis
-
-
PWY-8173
apratoxin A biosynthesis
-
-
PWY-8361
arachidonate biosynthesis I (6-desaturase, lower eukaryotes)
-
-
PWY-5353
arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)
-
-
PWY-7601
arachidonate biosynthesis V (8-detaturase, mammals)
-
-
PWY-7725
arachidonate metabolites biosynthesis
-
-
PWY-8397
Arg/N-end rule pathway (eukaryotic)
-
-
PWY-7799
arginine dependent acid resistance
-
-
PWY0-1299
aromatic biogenic amine degradation (bacteria)
-
-
PWY-7431
arsenate detoxification I
-
-
PWY-8264
arsenic detoxification (mammals)
-
-
PWY-4202
arsenite to oxygen electron transfer
-
-
PWY-4521
arsenite to oxygen electron transfer (via azurin)
-
-
PWY-7429
ascorbate recycling (cytosolic)
-
-
PWY-6370
aspirin triggered resolvin D biosynthesis
-
-
PWY66-395
aspirin triggered resolvin E biosynthesis
-
-
PWY66-394
ATP biosynthesis
-
-
PWY-7980
atromentin biosynthesis
-
-
PWY-7518
bacterial bioluminescence
-
-
PWY-7723
baicalein degradation (hydrogen peroxide detoxification)
-
-
PWY-7214
benzoate biosynthesis I (CoA-dependent, beta-oxidative)
-
-
PWY-6443
benzoyl-CoA biosynthesis
-
-
PWY-6458
benzoyl-CoA degradation I (aerobic)
-
-
PWY-1361
beta-(1,4)-mannan degradation
-
-
PWY-7456
beta-1,4-D-mannosyl-N-acetyl-D-glucosamine degradation
-
-
PWY-7586
beta-D-glucuronide and D-glucuronate degradation
-
-
PWY-7247
betanidin degradation
-
-
PWY-5461
Bifidobacterium shunt
-
-
P124-PWY
biosynthesis of Lewis epitopes (H. pylori)
-
-
PWY-7833
biotin-carboxyl carrier protein assembly
-
-
PWY0-1264
bis(guanylyl molybdopterin) cofactor sulfurylation
-
-
PWY-8164
bisabolene biosynthesis (engineered)
-
-
PWY-7102
bisucaberin biosynthesis
-
-
PWY-6381
brassicicene C biosynthesis
-
-
PWY-7517
bryostatin biosynthesis
-
-
PWY-8047
bupropion degradation
-
-
PWY66-241
butachlor degradation
-
-
PWY-7771
butanol and isobutanol biosynthesis (engineered)
-
-
PWY-7396
C20 prostanoid biosynthesis
-
-
PWY66-374
C4 photosynthetic carbon assimilation cycle, NAD-ME type
-
-
PWY-7115
C4 photosynthetic carbon assimilation cycle, NADP-ME type
-
-
PWY-241
C4 photosynthetic carbon assimilation cycle, PEPCK type
-
-
PWY-7117
cadaverine biosynthesis
-
-
PWY0-1601
caffeine biosynthesis I
-
-
PWY-5037
caffeine biosynthesis II (via paraxanthine)
-
-
PWY-5038
Calvin-Benson-Bassham cycle
-
-
CALVIN-PWY
camalexin biosynthesis
-
-
CAMALEXIN-SYN
canavanine degradation
-
-
PWY-31
cannabinoid biosynthesis
-
-
PWY-5140
capsaicin biosynthesis
-
-
PWY-5710
cardiolipin and phosphatidylethanolamine biosynthesis (Xanthomonas)
-
-
PWY-7509
cardiolipin biosynthesis I
-
-
PWY-5668
cardiolipin biosynthesis II
-
-
PWY-5269
cardiolipin biosynthesis III
-
-
PWY0-1545
CDP-6-deoxy-D-gulose biosynthesis
-
-
PWY-8139
CDP-diacylglycerol biosynthesis I
-
-
PWY-5667
CDP-diacylglycerol biosynthesis II
-
-
PWY0-1319
CDP-diacylglycerol biosynthesis III
-
-
PWY-5981
cell-surface glycoconjugate-linked phosphocholine biosynthesis
-
-
PWY-7886
ceramide and sphingolipid recycling and degradation (yeast)
-
-
PWY-7119
ceramide de novo biosynthesis
-
-
PWY3DJ-12
ceramide degradation (generic)
-
-
PWY-6483
ceramide degradation by alpha-oxidation
-
-
PWY66-388
chitin biosynthesis
-
-
PWY-6981
chitin deacetylation
-
-
PWY-7118
chitin degradation II (Vibrio)
-
-
PWY-6902
chitin degradation III (Serratia)
-
-
PWY-7822
chitin derivatives degradation
-
-
PWY-6906
chlorogenic acid degradation
-
-
PWY-6781
cholesterol biosynthesis (algae, late side-chain reductase)
-
-
PWY-8191
cholesterol biosynthesis (diatoms)
-
-
PWY-8239
cholesterol biosynthesis (plants, early side-chain reductase)
-
-
PWY18C3-1
cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
-
-
PWY66-3
cholesterol degradation to androstenedione I (cholesterol oxidase)
-
-
PWY-6945
cholesterol degradation to androstenedione II (cholesterol dehydrogenase)
-
-
PWY-6946
choline biosynthesis I
-
-
PWY-3385
choline biosynthesis III
-
-
PWY-3561
cis-geranyl-CoA degradation
-
-
PWY-6672
cis-vaccenate biosynthesis
cis-zeatin biosynthesis
-
-
PWY-2781
CMP phosphorylation
-
-
PWY-7205
CMP-legionaminate biosynthesis I
-
-
PWY-6749
CO2 fixation into oxaloacetate (anaplerotic)
-
-
PWYQT-4429
coenzyme A biosynthesis I (bacteria)
-
-
COA-PWY
coenzyme A biosynthesis II (eukaryotic)
-
-
PWY-7851
coenzyme A biosynthesis III (archaea)
-
-
PWY-8342
coenzyme B biosynthesis
-
-
P241-PWY
coenzyme M biosynthesis II
-
-
PWY-6643
colanic acid building blocks biosynthesis
-
-
COLANSYN-PWY
colupulone and cohumulone biosynthesis
-
-
PWY-5133
complex N-linked glycan biosynthesis (plants)
-
-
PWY-7920
complex N-linked glycan biosynthesis (vertebrates)
-
-
PWY-7426
conversion of succinate to propanoate
-
-
PWY0-43
creatine phosphate biosynthesis
-
-
PWY-6158
crepenynate biosynthesis
-
-
PWY-6013
crotonate fermentation (to acetate and cyclohexane carboxylate)
-
-
PWY-7401
curacin A biosynthesis
-
-
PWY-8358
cutin biosynthesis
-
-
PWY-321
cyanate degradation
cyclic electron flow
-
-
PWY-8270
cytidylyl molybdenum cofactor sulfurylation
-
-
PWY-8165
cytochrome c biogenesis (system II type)
-
-
PWY-8146
cytochrome c biogenesis (system III type)
-
-
PWY-8145
cytosolic NADPH production (yeast)
-
-
PWY-7268
D-fructuronate degradation
-
-
PWY-7242
D-galactose degradation I (Leloir pathway)
-
-
PWY-6317
D-galactose detoxification
-
-
PWY-3821
D-galacturonate degradation I
-
-
GALACTUROCAT-PWY
D-glucosaminate degradation
-
-
PWY-7310
D-glucuronate degradation I
-
-
PWY-5525
D-lactate to cytochrome bo oxidase electron transfer
-
-
PWY0-1565
D-mannose degradation I
-
-
MANNCAT-PWY
D-mannose degradation II
-
-
PWY3O-1743
D-myo-inositol (1,4,5)-trisphosphate biosynthesis
-
-
PWY-6351
D-myo-inositol (1,4,5)-trisphosphate degradation
-
-
PWY-6363
D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis
-
-
PWY-6366
D-myo-inositol-5-phosphate metabolism
-
-
PWY-6367
D-sorbitol biosynthesis I
-
-
PWY-5054
D-xylose degradation to ethylene glycol (engineered)
-
-
PWY-7178
degradation of aromatic, nitrogen containing compounds
-
-
dehydrophos biosynthesis
-
-
PWY-6682
desferrioxamine B biosynthesis
-
-
PWY-6376
desferrioxamine E biosynthesis
-
-
PWY-6375
detoxification of reactive carbonyls in chloroplasts
-
-
PWY-6786
di-homo-gamma-linolenate metabolites biosynthesis
-
-
PWY-8396
di-myo-inositol phosphate biosynthesis
-
-
PWY-6664
diacylglycerol and triacylglycerol biosynthesis
-
-
TRIGLSYN-PWY
diethylphosphate degradation
-
-
PWY-5491
dimorphecolate biosynthesis
-
-
PWY-5368
docosahexaenoate biosynthesis I (lower eukaryotes)
-
-
PWY-7053
docosahexaenoate biosynthesis III (6-desaturase, mammals)
-
-
PWY-7606
docosahexaenoate metabolites biosynthesis
-
-
PWY-8400
dolichol and dolichyl phosphate biosynthesis
dopamine degradation
-
-
PWY6666-2
dTDP-beta-L-rhamnose biosynthesis
-
-
DTDPRHAMSYN-PWY
dTMP de novo biosynthesis (mitochondrial)
-
-
PWY66-385
dZTP biosynthesis
-
-
PWY-8289
Entner-Doudoroff pathway I
-
-
PWY-8004
Entner-Doudoroff pathway II (non-phosphorylative)
-
-
NPGLUCAT-PWY
Entner-Doudoroff pathway III (semi-phosphorylative)
-
-
PWY-2221
Entner-Doudoroff shunt
-
-
ENTNER-DOUDOROFF-PWY
epoxysqualene biosynthesis
-
-
PWY-5670
ergosterol biosynthesis I
-
-
PWY-6075
ergosterol biosynthesis II
-
-
PWY-7154
ergothioneine biosynthesis I (bacteria)
-
-
PWY-7255
erythritol biosynthesis I
-
-
PWY-8372
erythritol biosynthesis II
-
-
PWY-8373
Escherichia coli serotype O:127 O antigen biosynthesis
-
-
PWY-8231
Escherichia coli serotype O:86 O antigen biosynthesis
-
-
PWY-7290
ethanol degradation I
-
-
ETOH-ACETYLCOA-ANA-PWY
ethanol degradation II
-
-
PWY66-21
ethanol degradation III
-
-
PWY66-161
ethanol degradation IV
-
-
PWY66-162
ethanolamine utilization
-
-
PWY0-1477
ethene biosynthesis I (plants)
-
-
ETHYL-PWY
ethene biosynthesis III (microbes)
-
-
PWY-6854
ethene biosynthesis IV (engineered)
-
-
PWY-7126
ethene biosynthesis V (engineered)
-
-
PWY-7124
even iso-branched-chain fatty acid biosynthesis
-
-
PWY-8175
fatty acid beta-oxidation I (generic)
-
-
FAO-PWY
fatty acid beta-oxidation II (plant peroxisome)
-
-
PWY-5136
fatty acid beta-oxidation IV (unsaturated, even number)
-
-
PWY-5138
fatty acid beta-oxidation VI (mammalian peroxisome)
-
-
PWY66-391
fatty acid beta-oxidation VII (yeast peroxisome)
-
-
PWY-7288
fatty acid biosynthesis initiation (mitochondria)
-
-
PWY66-429
fatty acid biosynthesis initiation (plant mitochondria)
-
-
PWY-6799
fatty acid biosynthesis initiation (type I)
-
-
PWY-5966-1
fatty acid biosynthesis initiation (type II)
-
-
PWY-4381
fatty acid elongation -- saturated
-
-
FASYN-ELONG-PWY
fatty acid salvage
-
-
PWY-7094
Fe(II) oxidation
-
-
PWY-6692
FeMo cofactor biosynthesis
-
-
PWY-7710
ferrichrome A biosynthesis
-
-
PWY-7571
flavin biosynthesis I (bacteria and plants)
-
-
RIBOSYN2-PWY
flavin biosynthesis III (fungi)
-
-
PWY-6168
flavin salvage
-
-
PWY66-366
fluoroacetate and fluorothreonine biosynthesis
-
-
PWY-6644
fluoroacetate degradation
-
-
PWY-6646
folate polyglutamylation
folate transformations I
-
-
PWY-2201
folate transformations II (plants)
-
-
PWY-3841
folate transformations III (E. coli)
-
-
1CMET2-PWY
formaldehyde assimilation I (serine pathway)
-
-
PWY-1622
formaldehyde assimilation II (assimilatory RuMP Cycle)
-
-
PWY-1861
formaldehyde assimilation III (dihydroxyacetone cycle)
-
-
P185-PWY
formaldehyde oxidation I
-
-
RUMP-PWY
formaldehyde oxidation II (glutathione-dependent)
-
-
PWY-1801
formaldehyde oxidation VII (THF pathway)
-
-
PWY-7909
formate assimilation into 5,10-methylenetetrahydrofolate
-
-
PWY-1722
formate to nitrite electron transfer
-
-
PWY0-1585
fosfomycin biosynthesis
-
-
PWY-5757
FR-900098 and FR-33289 antibiotics biosynthesis
-
-
PWY-7419
fructose 2,6-bisphosphate biosynthesis
-
-
PWY66-423
fusicoccin A biosynthesis
-
-
PWY-6659
gallate degradation III (anaerobic)
-
-
P3-PWY
gamma-linolenate biosynthesis II (animals)
-
-
PWY-6000
GDP-alpha-D-glucose biosynthesis
-
-
PWY-5661
GDP-mannose biosynthesis
-
-
PWY-5659
geranylgeranyl diphosphate biosynthesis
-
-
PWY-5120
gliotoxin biosynthesis
-
-
PWY-7533
gluconeogenesis I
-
-
GLUCONEO-PWY
gluconeogenesis II (Methanobacterium thermoautotrophicum)
-
-
PWY-6142
gluconeogenesis III
-
-
PWY66-399
glucose and glucose-1-phosphate degradation
-
-
GLUCOSE1PMETAB-PWY
glucose degradation (oxidative)
-
-
DHGLUCONATE-PYR-CAT-PWY
glucosinolate biosynthesis from dihomomethionine
-
-
PWYQT-4471
glucosinolate biosynthesis from hexahomomethionine
-
-
PWYQT-4475
glucosinolate biosynthesis from homomethionine
-
-
PWY-1187
glucosinolate biosynthesis from pentahomomethionine
-
-
PWYQT-4474
glucosinolate biosynthesis from phenylalanine
-
-
PWY-2821
glucosinolate biosynthesis from tetrahomomethionine
-
-
PWYQT-4473
glucosinolate biosynthesis from trihomomethionine
-
-
PWYQT-4472
glucosinolate biosynthesis from tryptophan
-
-
PWY-601
glucosinolate biosynthesis from tyrosine
-
-
PWY-7901
glucosylglycerol biosynthesis
-
-
PWY-7902
glutaminyl-tRNAgln biosynthesis via transamidation
-
-
PWY-5921
glutaryl-CoA degradation
-
-
PWY-5177
glutathione biosynthesis
-
-
GLUTATHIONESYN-PWY
glutathione-mediated detoxification I
-
-
PWY-4061
glutathione-mediated detoxification II
-
-
PWY-6842
glutathione-peroxide redox reactions
-
-
PWY-4081
glutathionylspermidine biosynthesis
-
-
PWY-4121
glycerol degradation I
-
-
PWY-4261
glycerol degradation II
-
-
PWY-6131
glycerol degradation to butanol
-
-
PWY-7003
glycerol-3-phosphate shuttle
-
-
PWY-6118
glycerol-3-phosphate to cytochrome bo oxidase electron transfer
-
-
PWY0-1561
glycerol-3-phosphate to fumarate electron transfer
-
-
PWY0-1582
glycerol-3-phosphate to hydrogen peroxide electron transport
-
-
PWY0-1591
glycerophosphodiester degradation
-
-
PWY-6952
glycine betaine degradation I
-
-
PWY-3661
glycine betaine degradation II (mammalian)
-
-
PWY-3661-1
glycine betaine degradation III
-
-
PWY-8325
glycine biosynthesis I
-
-
GLYSYN-PWY
glycine biosynthesis II
-
-
GLYCINE-SYN2-PWY
glycine cleavage
-
-
GLYCLEAV-PWY
glycine degradation (reductive Stickland reaction)
-
-
PWY-8015
glycogen biosynthesis I (from ADP-D-Glucose)
-
-
GLYCOGENSYNTH-PWY
glycogen biosynthesis III (from alpha-maltose 1-phosphate)
-
-
PWY-7900
glycogen degradation I
-
-
GLYCOCAT-PWY
glycogen degradation II
-
-
PWY-5941
glycolysis I (from glucose 6-phosphate)
-
-
GLYCOLYSIS
glycolysis II (from fructose 6-phosphate)
-
-
PWY-5484
glycolysis III (from glucose)
-
-
ANAGLYCOLYSIS-PWY
glycolysis IV
-
-
PWY-1042
glycolysis V (Pyrococcus)
-
-
P341-PWY
glyoxylate assimilation
-
-
PWY-5744
glyoxylate cycle
-
-
GLYOXYLATE-BYPASS
glyphosate degradation III
-
-
PWY-7807
gondoate biosynthesis (anaerobic)
-
-
PWY-7663
guanine and guanosine salvage I
-
-
PWY-6620
guanine and guanosine salvage II
-
-
PWY-6599
guanosine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7226
guanosine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7222
guanosine nucleotides degradation I
-
-
PWY-6607
guanosine nucleotides degradation II
-
-
PWY-6606
guanosine nucleotides degradation III
-
-
PWY-6608
guanosine ribonucleotides de novo biosynthesis
-
-
PWY-7221
H. pylori 26695 O-antigen biosynthesis
-
-
PWY2DNV-5
heme b biosynthesis I (aerobic)
-
-
HEME-BIOSYNTHESIS-II
heme b biosynthesis II (oxygen-independent)
-
-
HEMESYN2-PWY
heme b biosynthesis V (aerobic)
-
-
HEME-BIOSYNTHESIS-II-1
heme degradation I
-
-
PWY-5874
heptadecane biosynthesis
-
-
PWY-6622
heterolactic fermentation
-
-
P122-PWY
homocysteine and cysteine interconversion
-
-
PWY-801
homoglutathione biosynthesis
-
-
PWY-6840
homospermidine biosynthesis I
-
-
PWY-5907
homospermidine biosynthesis II
-
-
PWY-8149
hydrogen sulfide biosynthesis II (mammalian)
-
-
PWY66-426
hydrogen to fumarate electron transfer
-
-
PWY0-1576
hydroxylated fatty acid biosynthesis (plants)
-
-
PWY-6433
i antigen and I antigen biosynthesis
-
-
PWY-7837
icosapentaenoate biosynthesis I (lower eukaryotes)
-
-
PWY-6958
icosapentaenoate biosynthesis II (6-desaturase, mammals)
-
-
PWY-7049
icosapentaenoate biosynthesis III (8-desaturase, mammals)
-
-
PWY-7724
icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)
-
-
PWY-7602
icosapentaenoate metabolites biosynthesis
-
-
PWY-8399
incomplete reductive TCA cycle
-
-
P42-PWY
indole glucosinolate activation (intact plant cell)
-
-
PWYQT-4477
indole-3-acetate biosynthesis II
-
-
PWY-581
indole-3-acetate biosynthesis III (bacteria)
-
-
PWY-3161
indole-3-acetate biosynthesis IV (bacteria)
-
-
PWY-5025
indole-3-acetate biosynthesis VI (bacteria)
-
-
TRPIAACAT-PWY
inosine 5'-phosphate degradation
-
-
PWY-5695
inositol diphosphates biosynthesis
-
-
PWY-6369
inulin degradation
-
-
PWY-8314
isoprene biosynthesis II (engineered)
-
-
PWY-7391
isopropanol biosynthesis (engineered)
-
-
PWY-6876
itaconate degradation
-
-
PWY-5749
jadomycin biosynthesis
-
-
PWY-6679
juniperonate biosynthesis
-
-
PWY-7619
justicidin B biosynthesis
-
-
PWY-6824
ketogenesis
-
-
PWY66-367
ketogluconate metabolism
ketolysis
-
-
PWY66-368
L-alanine biosynthesis II
-
-
ALANINE-SYN2-PWY
L-alanine biosynthesis III
-
-
PWY0-1021
L-alanine degradation I
-
-
ALADEG-PWY
L-alanine degradation II (to D-lactate)
-
-
ALACAT2-PWY
L-alanine degradation III
-
-
ALANINE-DEG3-PWY
L-alanine degradation V (oxidative Stickland reaction)
-
-
PWY-8189
L-alanine degradation VI (reductive Stickland reaction)
-
-
PWY-8188
L-arabinose degradation II
-
-
PWY-5515
L-arginine degradation I (arginase pathway)
-
-
ARGASEDEG-PWY
L-arginine degradation III (arginine decarboxylase/agmatinase pathway)
-
-
PWY0-823
L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway)
-
-
ARGDEG-III-PWY
L-arginine degradation VI (arginase 2 pathway)
-
-
ARG-PRO-PWY
L-arginine degradation VII (arginase 3 pathway)
-
-
ARG-GLU-PWY
L-arginine degradation X (arginine monooxygenase pathway)
-
-
ARGDEG-V-PWY
L-arginine degradation XIII (reductive Stickland reaction)
-
-
PWY-8187
L-ascorbate biosynthesis IV (animals, D-glucuronate pathway)
-
-
PWY3DJ-35471
L-ascorbate biosynthesis VI (plants, myo-inositol pathway)
-
-
PWY-8142
L-ascorbate biosynthesis VIII (engineered pathway)
-
-
PWY-7165
L-ascorbate degradation II (bacterial, aerobic)
-
-
PWY-6961
L-ascorbate degradation III
-
-
PWY-6960
L-asparagine biosynthesis I
-
-
ASPARAGINE-BIOSYNTHESIS
L-asparagine biosynthesis II
-
-
ASPARAGINESYN-PWY
L-asparagine biosynthesis III (tRNA-dependent)
-
-
PWY490-4
L-asparagine degradation I
-
-
ASPARAGINE-DEG1-PWY
L-asparagine degradation III (mammalian)
-
-
ASPARAGINE-DEG1-PWY-1
L-aspartate biosynthesis
-
-
ASPARTATESYN-PWY
L-aspartate degradation I
-
-
ASPARTATE-DEG1-PWY
L-aspartate degradation II (aerobic)
-
-
PWY-8291
L-aspartate degradation III (anaerobic)
-
-
PWY-8294
L-carnitine degradation II
-
-
PWY-3641
L-citrulline biosynthesis
-
-
CITRULBIO-PWY
L-cysteine biosynthesis III (from L-homocysteine)
-
-
HOMOCYSDEGR-PWY
L-cysteine degradation III
-
-
PWY-5329
L-glutamate biosynthesis I
-
-
GLUTSYN-PWY
L-glutamate degradation I
-
-
GLUTAMATE-DEG1-PWY
L-glutamate degradation II
-
-
GLUTDEG-PWY
L-glutamate degradation V (via hydroxyglutarate)
-
-
P162-PWY
L-glutamate degradation VII (to butanoate)
-
-
GLUDEG-II-PWY
L-glutamate degradation XI (reductive Stickland reaction)
-
-
PWY-8190
L-glutamine biosynthesis I
-
-
GLNSYN-PWY
L-glutamine degradation I
-
-
GLUTAMINDEG-PWY
L-histidine degradation III
-
-
PWY-5030
L-histidine degradation V
-
-
PWY-5031
L-isoleucine biosynthesis I (from threonine)
-
-
ILEUSYN-PWY
L-isoleucine biosynthesis III
-
-
PWY-5103
L-isoleucine biosynthesis V
-
-
PWY-5108
L-isoleucine degradation II
-
-
PWY-5078
L-lactaldehyde degradation (aerobic)
-
-
PWY0-1317
L-leucine degradation I
-
-
LEU-DEG2-PWY
L-leucine degradation III
-
-
PWY-5076
L-lysine biosynthesis IV
-
-
LYSINE-AMINOAD-PWY
L-lysine biosynthesis V
-
-
PWY-3081
L-lysine degradation I
-
-
PWY0-461
L-lysine degradation II (L-pipecolate pathway)
-
-
PWY66-425
L-lysine degradation X
-
-
PWY-6328
L-lysine degradation XI
-
-
LYSINE-DEG1-PWY
L-lysine fermentation to acetate and butanoate
-
-
P163-PWY
L-malate degradation II
-
-
PWY-7686
L-methionine biosynthesis I
-
-
HOMOSER-METSYN-PWY
L-methionine biosynthesis II
-
-
PWY-702
L-methionine degradation I (to L-homocysteine)
-
-
METHIONINE-DEG1-PWY
L-methionine degradation III
-
-
PWY-5082
L-Ndelta-acetylornithine biosynthesis
-
-
PWY-6922
L-phenylalanine biosynthesis I
-
-
PHESYN
L-phenylalanine biosynthesis III (cytosolic, plants)
-
-
PWY-7432
L-phenylalanine degradation II (anaerobic)
-
-
ANAPHENOXI-PWY
L-phenylalanine degradation III
-
-
PWY-5079
L-phenylalanine degradation IV (mammalian, via side chain)
-
-
PWY-6318
L-phenylalanine degradation V
-
-
PWY-7158
L-phenylalanine degradation VI (reductive Stickland reaction)
-
-
PWY-8014
L-proline biosynthesis I (from L-glutamate)
-
-
PROSYN-PWY
L-proline biosynthesis III (from L-ornithine)
-
-
PWY-3341
L-proline degradation I
-
-
PROUT-PWY
L-proline degradation II (reductive Stickland reaction)
-
-
PWY-8186
L-rhamnose degradation II
-
-
PWY-6713
L-selenocysteine biosynthesis I (bacteria)
-
-
PWY0-901
L-selenocysteine biosynthesis II (archaea and eukaryotes)
-
-
PWY-6281
L-serine biosynthesis I
-
-
SERSYN-PWY
L-threonine biosynthesis
-
-
HOMOSER-THRESYN-PWY
L-threonine degradation I
-
-
PWY-5437
L-threonine degradation II
-
-
THREONINE-DEG2-PWY
L-threonine degradation III (to methylglyoxal)
-
-
THRDLCTCAT-PWY
L-tryptophan biosynthesis
-
-
TRPSYN-PWY
L-tryptophan degradation I (via anthranilate)
-
-
TRPCAT-PWY
L-tryptophan degradation IV (via indole-3-lactate)
-
-
TRPKYNCAT-PWY
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
-
-
PWY-5651
L-tryptophan degradation V (side chain pathway)
-
-
PWY-3162
L-tryptophan degradation VI (via tryptamine)
-
-
PWY-3181
L-tryptophan degradation VIII (to tryptophol)
-
-
PWY-5081
L-tryptophan degradation X (mammalian, via tryptamine)
-
-
PWY-6307
L-tryptophan degradation XI (mammalian, via kynurenine)
-
-
PWY-6309
L-tryptophan degradation XIII (reductive Stickland reaction)
-
-
PWY-8017
L-tyrosine biosynthesis I
-
-
TYRSYN
L-tyrosine degradation I
-
-
TYRFUMCAT-PWY
L-tyrosine degradation II
-
-
PWY-5151
L-tyrosine degradation III
-
-
PWY3O-4108
L-tyrosine degradation IV (to 4-methylphenol)
-
-
PWY-7514
L-tyrosine degradation V (reductive Stickland reaction)
-
-
PWY-8016
L-valine biosynthesis
-
-
VALSYN-PWY
L-valine degradation II
-
-
PWY-5057
lactate biosynthesis (archaea)
-
-
PWY-5197
lactate fermentation to acetate, CO2 and hydrogen (Desulfovibrionales)
-
-
PWY-8377
lacto-series glycosphingolipids biosynthesis
-
-
PWY-7839
lanosterol biosynthesis
-
-
PWY-6132
linoleate biosynthesis I (plants)
-
-
PWY-5995
linoleate biosynthesis II (animals)
-
-
PWY-6001
linoleate metabolites biosynthesis
-
-
PWY-8395
lipid A-core biosynthesis (E. coli K-12)
-
-
LIPA-CORESYN-PWY
lipid A-core biosynthesis (Salmonella)
-
-
PWY1R65-1
lipid IVA biosynthesis (2,3-diamino-2,3-dideoxy-D-glucopyranose-containing)
-
-
PWY2B4Q-4
lipid IVA biosynthesis (E. coli)
-
-
NAGLIPASYN-PWY
lipid IVA biosynthesis (generic)
-
-
PWY-8283
lipid IVA biosynthesis (H. pylori)
-
-
PWYI-14
lipid IVA biosynthesis (P. gingivalis)
-
-
PWY-8245
lipid IVA biosynthesis (P. putida)
-
-
PWY-8073
lipid IVA biosynthesis (Vibrio cholerae serogroup O1 El Tor)
-
-
PWY2G6Z-2
lipoxin biosynthesis
-
-
PWY66-392
long chain fatty acid ester synthesis (engineered)
-
-
PWY-6873
long-chain fatty acid activation
-
-
PWY-5143
lupanine biosynthesis
-
-
PWY-5468
lupulone and humulone biosynthesis
-
-
PWY-5132
luteolin triglucuronide degradation
-
-
PWY-7445
malate/L-aspartate shuttle pathway
-
-
MALATE-ASPARTATE-SHUTTLE-PWY
mannitol biosynthesis
-
-
PWY-3881
mannitol degradation II
-
-
PWY-3861
maresin biosynthesis
-
-
PWY-8356
matairesinol biosynthesis
-
-
PWY-5466
melatonin degradation I
-
-
PWY-6398
melatonin degradation II
-
-
PWY-6399
melibiose degradation
-
-
PWY0-1301
menaquinol-4 biosynthesis II
-
-
PWY-7998
Methanobacterium thermoautotrophicum biosynthetic metabolism
-
-
PWY-6146
methanogenesis from acetate
-
-
METH-ACETATE-PWY
methanol oxidation to formaldehyde IV
-
-
PWY-5506
methiin metabolism
-
-
PWY-7614
methyl indole-3-acetate interconversion
-
-
PWY-6303
methyl ketone biosynthesis (engineered)
-
-
PWY-7007
methyl phomopsenoate biosynthesis
-
-
PWY-7721
methyl tert-butyl ether degradation
-
-
PWY-7779
methylaspartate cycle
methylerythritol phosphate pathway I
-
-
NONMEVIPP-PWY
methylerythritol phosphate pathway II
-
-
PWY-7560
methylglyoxal degradation I
-
-
PWY-5386
methylglyoxal degradation IV
-
-
PWY-5459
methylglyoxal degradation V
-
-
PWY-5458
methylglyoxal degradation VI
-
-
MGLDLCTANA-PWY
methylglyoxal degradation VIII
-
-
PWY-5386-1
methylphosphonate biosynthesis
-
-
PWY-8067
methylsalicylate degradation
-
-
PWY18C3-24
methylwyosine biosynthesis
-
-
PWY-7285
mevalonate pathway I (eukaryotes and bacteria)
-
-
PWY-922
mevalonate pathway II (haloarchaea)
-
-
PWY-6174
mevalonate pathway III (Thermoplasma)
-
-
PWY-7524
mevalonate pathway IV (archaea)
-
-
PWY-8125
mitochondrial NADPH production (yeast)
-
-
PWY-7269
mixed acid fermentation
-
-
FERMENTATION-PWY
molybdopterin biosynthesis
-
-
PWY-6823
mRNA capping I
-
-
PWY-7375
mRNA capping II
-
-
PWY-7379
mucin core 1 and core 2 O-glycosylation
-
-
PWY-7433
mucin core 3 and core 4 O-glycosylation
-
-
PWY-7435
mupirocin biosynthesis
-
-
PWY-8012
muropeptide degradation
-
-
PWY0-1546
mycobactin biosynthesis
-
-
PWY185E-1
mycolate biosynthesis
-
-
PWYG-321
mycolyl-arabinogalactan-peptidoglycan complex biosynthesis
-
-
PWY-6397
mycothiol biosynthesis
-
-
PWY1G-0
myo-inositol biosynthesis
NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde
-
-
PWY-5653
NAD de novo biosynthesis I
-
-
PYRIDNUCSYN-PWY
NAD de novo biosynthesis III
-
-
PWY-8352
NAD de novo biosynthesis IV (anaerobic)
-
-
PWY-8277
NAD salvage (plants)
-
-
PWY-5381
NAD salvage pathway I (PNC VI cycle)
-
-
PYRIDNUCSAL-PWY
NAD salvage pathway II (PNC IV cycle)
-
-
PWY-7761
NAD salvage pathway III (to nicotinamide riboside)
-
-
NAD-BIOSYNTHESIS-II
NAD salvage pathway V (PNC V cycle)
-
-
PWY3O-4107
NAD(P)/NADPH interconversion
-
-
PWY-5083
NADH to cytochrome bd oxidase electron transfer I
-
-
PWY0-1334
NADH to cytochrome bd oxidase electron transfer II
-
-
PWY0-1568
NADH to cytochrome bo oxidase electron transfer I
-
-
PWY0-1335
NADH to cytochrome bo oxidase electron transfer II
-
-
PWY0-1567
NADH to fumarate electron transfer
-
-
PWY0-1336
NADPH to cytochrome c oxidase via plastocyanin
-
-
PWY-8271
neolacto-series glycosphingolipids biosynthesis
-
-
PWY-7841
nicotine degradation IV
-
-
PWY66-201
nicotine degradation V
-
-
PWY66-221
nitrate reduction I (denitrification)
-
-
DENITRIFICATION-PWY
nitrate reduction IX (dissimilatory)
-
-
PWY0-1581
nitrate reduction VII (denitrification)
-
-
PWY-6748
nitrate reduction VIIIb (dissimilatory)
-
-
PWY0-1573
nitrate reduction X (dissimilatory, periplasmic)
-
-
PWY0-1584
nitric oxide biosynthesis II (mammals)
-
-
PWY-4983
nitrifier denitrification
-
-
PWY-7084
nitrite-dependent anaerobic methane oxidation
-
-
PWY-6523
nitrogen remobilization from senescing leaves
-
-
PWY-6549
nocardicin A biosynthesis
-
-
PWY-7797
nonaprenyl diphosphate biosynthesis I
-
-
PWY-5805
nonaprenyl diphosphate biosynthesis II
-
-
PWY-6520
noradrenaline and adrenaline degradation
-
-
PWY-6342
nucleoside and nucleotide degradation (archaea)
-
-
PWY-5532
O-antigen building blocks biosynthesis (E. coli)
-
-
OANTIGEN-PWY
octane oxidation
octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)
-
-
PWY-7388
odd iso-branched-chain fatty acid biosynthesis
-
-
PWY-8174
oleandomycin activation/inactivation
-
-
PWY-6972
oleate beta-oxidation
-
-
PWY0-1337
oleate biosynthesis I (plants)
-
-
PWY-5147
oleate biosynthesis II (animals and fungi)
-
-
PWY-5996
oleate biosynthesis III (cyanobacteria)
-
-
PWY-7587
oleate biosynthesis IV (anaerobic)
-
-
PWY-7664
ophiobolin F biosynthesis
-
-
PWY-7720
ophthalmate biosynthesis
-
-
PWY-8043
palmitate biosynthesis I (type I fatty acid synthase)
-
-
PWY-5994
palmitate biosynthesis II (type II fatty acid synthase)
-
-
PWY-5971
palmitate biosynthesis III
-
-
PWY-8279
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)
-
-
PWY-6282
palmitoleate biosynthesis IV (fungi and animals)
-
-
PWY3O-1801
palmitoyl ethanolamide biosynthesis
-
-
PWY-8055
partial TCA cycle (obligate autotrophs)
-
-
PWY-5913
paspaline biosynthesis
-
-
PWY-7492
patulin biosynthesis
-
-
PWY-7490
pectin degradation II
-
-
PWY-7248
pederin biosynthesis
-
-
PWY-8049
pentachlorophenol degradation
-
-
PCPDEG-PWY
pentose phosphate pathway (non-oxidative branch) I
-
-
NONOXIPENT-PWY
pentose phosphate pathway (non-oxidative branch) II
-
-
PWY-8178
pentose phosphate pathway (oxidative branch) I
-
-
OXIDATIVEPENT-PWY
pentose phosphate pathway (partial)
-
-
P21-PWY
peptido-conjugates in tissue regeneration biosynthesis
-
-
PWY-8355
peptidoglycan maturation (meso-diaminopimelate containing)
-
-
PWY0-1586
peptidoglycan recycling I
-
-
PWY0-1261
peptidoglycan recycling II
-
-
PWY-7883
petroselinate biosynthesis
-
-
PWY-5367
phenylacetate degradation I (aerobic)
-
-
PWY0-321
phenylethanol biosynthesis
-
-
PWY-5751
phenylethylamine degradation I
-
-
2PHENDEG-PWY
phosalacine biosynthesis
-
-
PWY-7769
phosphate acquisition
-
-
PWY-6348
phosphatidate biosynthesis (yeast)
-
-
PWY-7411
phosphatidate metabolism, as a signaling molecule
-
-
PWY-7039
phosphatidylcholine acyl editing
-
-
PWY-6803
phosphatidylcholine biosynthesis I
-
-
PWY3O-450
phosphatidylcholine biosynthesis VII
-
-
PWY-7470
phosphatidylethanolamine biosynthesis II
-
-
PWY4FS-6
phosphatidylethanolamine biosynthesis III
-
-
PWY-6273
phosphatidylglycerol biosynthesis I
-
-
PWY4FS-7
phosphatidylglycerol biosynthesis II
-
-
PWY4FS-8
phosphatidylinositol biosynthesis I (bacteria)
-
-
PWY-6580
phosphatidylinositol biosynthesis II (eukaryotes)
-
-
PWY-7625
phosphatidylserine and phosphatidylethanolamine biosynthesis I
-
-
PWY-5669
phosphatidylserine biosynthesis I
-
-
PWY-7501
phosphatidylserine biosynthesis II
-
-
PWY-7506
phosphinothricin tripeptide biosynthesis
-
-
PWY-6322
phospholipases
-
-
LIPASYN-PWY
phospholipid desaturation
-
-
PWY-762
phospholipid remodeling (phosphatidate, yeast)
-
-
PWY-7417
phospholipid remodeling (phosphatidylcholine, yeast)
-
-
PWY-7416
phospholipid remodeling (phosphatidylethanolamine, yeast)
-
-
PWY-7409
phosphopantothenate biosynthesis I
-
-
PANTO-PWY
photorespiration I
-
-
PWY-181
photorespiration II
-
-
PWY-8362
photorespiration III
-
-
PWY-8363
photosynthesis light reactions
-
-
PWY-101
photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
-
-
PWY-7218
phytate degradation I
-
-
PWY-4702
phytochromobilin biosynthesis
-
-
PWY-7170
phytol degradation
-
-
PWY66-389
phytosterol biosynthesis (plants)
-
-
PWY-2541
plasmalogen biosynthesis I (aerobic)
-
-
PWY-7782
plasmalogen degradation
-
-
PWY-7783
platensimycin biosynthesis
-
-
PWY-8179
plaunotol biosynthesis
-
-
PWY-6691
polyhydroxydecanoate biosynthesis
-
-
PWY-6657
polyphosphate metabolism
-
-
PWY-8138
porphyran degradation
-
-
PWY-6815
ppGpp metabolism
-
-
PPGPPMET-PWY
proline to cytochrome bo oxidase electron transfer
-
-
PWY0-1544
propanethial S-oxide biosynthesis
-
-
PWY-5707
protectin biosynthesis
-
-
PWY-8357
protein N-glycosylation (Haloferax volcanii)
-
-
PWY-7661
protein N-glycosylation initial phase (eukaryotic)
-
-
MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
protein N-glycosylation processing of mannoproteins (cis-Golgi, yeast)
-
-
PWY-8323
protein N-glycosylation processing of proteins targeted for retention in cellular organelles (cis-Golgi, yeast)
-
-
PWY-8322
protein N-glycosylation processing phase (endoplasmic reticulum, yeast)
-
-
PWY-7918
protein N-glycosylation processing phase (plants and animals)
-
-
PWY-7919
protein O-mannosylation I (yeast)
-
-
PWY-7921
protein O-mannosylation II (mammals, core M1 and core M2)
-
-
PWY-7922
protein O-mannosylation III (mammals, core M3)
-
-
PWY-7979
protein S-nitrosylation and denitrosylation
-
-
PWY-7798
protein ubiquitination
-
-
PWY-7511
pseudouridine degradation
-
-
PWY-6019
purine deoxyribonucleosides degradation I
-
-
PWY-7179
purine deoxyribonucleosides degradation II
-
-
PWY-7179-1
purine deoxyribonucleosides salvage
-
-
PWY-7224
purine nucleobases degradation I (anaerobic)
-
-
P164-PWY
purine nucleobases degradation II (anaerobic)
-
-
PWY-5497
purine ribonucleosides degradation
-
-
PWY0-1296
putrescine biosynthesis I
-
-
PWY-40
putrescine biosynthesis II
-
-
PWY-43
putrescine biosynthesis III
-
-
PWY-46
putrescine degradation III
-
-
PWY-0
pyridoxal 5'-phosphate salvage I
-
-
PLPSAL-PWY
pyridoxal 5'-phosphate salvage II (plants)
-
-
PWY-7204
pyrimidine deoxyribonucleosides degradation
-
-
PWY-7181
pyrimidine deoxyribonucleosides salvage
-
-
PWY-7199
pyrimidine deoxyribonucleotide phosphorylation
-
-
PWY-7197
pyrimidine deoxyribonucleotides biosynthesis from CTP
-
-
PWY-7210
pyrimidine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7184
pyrimidine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7187
pyrimidine deoxyribonucleotides de novo biosynthesis III
-
-
PWY-6545
pyrimidine deoxyribonucleotides de novo biosynthesis IV
-
-
PWY-7198
pyrimidine deoxyribonucleotides dephosphorylation
-
-
PWY-7206
pyrimidine nucleobases salvage I
-
-
PWY-7183
pyrimidine nucleobases salvage II
-
-
PWY-7194
pyrimidine ribonucleosides degradation
-
-
PWY0-1295
pyrimidine ribonucleosides salvage I
-
-
PWY-7193
pyrimidine ribonucleosides salvage II
-
-
PWY-6556
pyrimidine ribonucleosides salvage III
-
-
PWY-7195
pyruvate decarboxylation to acetyl CoA I
-
-
PYRUVDEHYD-PWY
pyruvate decarboxylation to acetyl CoA II
-
-
PWY-6970
pyruvate decarboxylation to acetyl CoA III
-
-
PWY-8275
pyruvate fermentation to (R)-lactate
-
-
PWY-8274
pyruvate fermentation to (S)-lactate
-
-
PWY-5481
pyruvate fermentation to acetate I
-
-
P142-PWY
pyruvate fermentation to acetate II
-
-
PWY-5482
pyruvate fermentation to acetate III
-
-
PWY-5483
pyruvate fermentation to acetate IV
-
-
PWY-5485
pyruvate fermentation to acetate VI
-
-
PWY-5538
pyruvate fermentation to acetate VII
-
-
PWY-5600
pyruvate fermentation to acetate VIII
-
-
PWY-5768
pyruvate fermentation to acetoin III
-
-
PWY3O-440
pyruvate fermentation to acetone
-
-
PWY-6588
pyruvate fermentation to butanoate
-
-
CENTFERM-PWY
pyruvate fermentation to butanol I
-
-
PWY-6583
pyruvate fermentation to butanol II (engineered)
-
-
PWY-6883
pyruvate fermentation to ethanol I
-
-
PWY-5480
pyruvate fermentation to ethanol II
-
-
PWY-5486
pyruvate fermentation to ethanol III
-
-
PWY-6587
pyruvate fermentation to hexanol (engineered)
-
-
PWY-6863
pyruvate fermentation to isobutanol (engineered)
-
-
PWY-7111
pyruvate fermentation to propanoate I
-
-
P108-PWY
pyruvate to cytochrome bo oxidase electron transfer
-
-
PWY-7544
queuosine biosynthesis I (de novo)
-
-
PWY-6700
queuosine biosynthesis III (queuosine salvage)
-
-
PWY-8106
quinoxaline-2-carboxylate biosynthesis
-
-
PWY-7734
reactive oxygen species degradation
-
-
DETOX1-PWY-1
reductive acetyl coenzyme A pathway I (homoacetogenic bacteria)
-
-
CODH-PWY
reductive glycine pathway of autotrophic CO2 fixation
-
-
PWY-8303
reductive monocarboxylic acid cycle
-
-
PWY-5493
reductive TCA cycle I
-
-
P23-PWY
reductive TCA cycle II
-
-
PWY-5392
resolvin D biosynthesis
-
-
PWY66-397
retinol biosynthesis
-
-
PWY-6857
rhizocticin A and B biosynthesis
-
-
PWY-7510
ribose phosphorylation
-
-
RIBOKIN-PWY
ricinoleate biosynthesis
-
-
PWY-7618
roseoflavin biosynthesis
-
-
PWY-7863
rosmarinic acid biosynthesis I
-
-
PWY-5048
Rubisco shunt
-
-
PWY-5723
S-(6-hydroxy-4-methylhexan-4-yl)-L-cysteinylglycine degradation
-
-
PWY-8302
S-adenosyl-L-methionine biosynthesis
-
-
SAM-PWY
S-adenosyl-L-methionine salvage I
-
-
PWY-6151
S-adenosyl-L-methionine salvage II
-
-
PWY-5041
S-methyl-5'-thioadenosine degradation II
-
-
PWY-6756
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I
-
-
PWY-4361
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II
-
-
PWY-7174
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation III
-
-
PWY-8132
salidroside biosynthesis
-
-
PWY-6802
salinosporamide A biosynthesis
-
-
PWY-6627
Salmonella enterica serotype O:13 O antigen biosynthesis
-
-
PWY-8230
sciadonate biosynthesis
-
-
PWY-6598
sedoheptulose bisphosphate bypass
-
-
PWY0-1517
seleno-amino acid biosynthesis (plants)
-
-
PWY-6936
serotonin degradation
-
-
PWY-6313
sesamin biosynthesis
-
-
PWY-5469
sophorosyloxydocosanoate deacetylation
-
-
SOPHOROSYLOXYDOCOSANOATE-DEG-PWY
sorbitol biosynthesis II
-
-
PWY-5530
sorgoleone biosynthesis
-
-
PWY-5987
spermidine biosynthesis I
-
-
BSUBPOLYAMSYN-PWY
spermidine biosynthesis III
-
-
PWY-6834
spermine and spermidine degradation I
-
-
PWY-6117
spermine biosynthesis
-
-
ARGSPECAT-PWY
sphingolipid biosynthesis (mammals)
-
-
PWY-7277
sphingolipid biosynthesis (plants)
-
-
PWY-5129
sphingolipid biosynthesis (yeast)
-
-
SPHINGOLIPID-SYN-PWY
sphingomyelin metabolism
-
-
PWY3DJ-11281
sphingosine and sphingosine-1-phosphate metabolism
-
-
PWY3DJ-11470
sporopollenin precursors biosynthesis
-
-
PWY-6733
stachyose degradation
-
-
PWY-6527
starch biosynthesis
-
-
PWY-622
starch degradation I
-
-
PWY-842
starch degradation II
-
-
PWY-6724
starch degradation III
-
-
PWY-6731
starch degradation V
-
-
PWY-6737
stearate biosynthesis I (animals)
-
-
PWY-5972
stearate biosynthesis II (bacteria and plants)
-
-
PWY-5989
stearate biosynthesis III (fungi)
-
-
PWY3O-355
stearate biosynthesis IV
-
-
PWY-8280
stellatic acid biosynthesis
-
-
PWY-7736
sterol:steryl ester interconversion (yeast)
-
-
PWY-7424
stigma estolide biosynthesis
-
-
PWY-6453
streptomycin biosynthesis
-
-
PWY-5940
streptorubin B biosynthesis
-
-
PWY1A0-6120
suberin monomers biosynthesis
-
-
PWY-1121
succinate fermentation to butanoate
-
-
PWY-5677
succinate to chytochrome c oxidase via cytochrome c6
-
-
PWY1YI0-2
succinate to cytochrome bd oxidase electron transfer
-
-
PWY0-1353
succinate to cytochrome bo oxidase electron transfer
-
-
PWY0-1329
succinate to cytochrome c oxidase via plastocyanin
-
-
PWY1YI0-3
succinate to plastoquinol oxidase
-
-
PWY1YI0-8
sucrose biosynthesis I (from photosynthesis)
-
-
SUCSYN-PWY
sucrose biosynthesis II
-
-
PWY-7238
sucrose biosynthesis III
-
-
PWY-7347
sucrose degradation II (sucrose synthase)
-
-
PWY-3801
sucrose degradation III (sucrose invertase)
-
-
PWY-621
sucrose degradation IV (sucrose phosphorylase)
-
-
PWY-5384
sucrose degradation V (sucrose alpha-glucosidase)
-
-
PWY66-373
sulfide oxidation IV (mitochondria)
-
-
PWY-7927
sulfoacetaldehyde degradation I
-
-
PWY-1281
sulfolactate degradation II
-
-
PWY-6637
sulfolactate degradation III
-
-
PWY-6638
sulfur volatiles biosynthesis
-
-
PWY-6736
superoxide radicals degradation
-
-
DETOX1-PWY
superpathway of fatty acid biosynthesis initiation
-
-
FASYN-INITIAL-PWY
superpathway of fermentation (Chlamydomonas reinhardtii)
-
-
PWY4LZ-257
superpathway of glucose and xylose degradation
-
-
PWY-6901
superpathway of glycolysis and the Entner-Doudoroff pathway
-
-
GLYCOLYSIS-E-D
superpathway of glyoxylate cycle and fatty acid degradation
-
-
PWY-561
superpathway of L-aspartate and L-asparagine biosynthesis
-
-
ASPASN-PWY
superpathway of methylsalicylate metabolism
-
-
PWY18C3-25
superpathway of ornithine degradation
-
-
ORNDEG-PWY
superpathway of phospholipid biosynthesis II (plants)
-
-
PHOSLIPSYN2-PWY
superpathway of photosynthetic hydrogen production
-
-
PWY-7731
superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)
-
-
PWY0-166
superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis
-
-
PWY-7328
taurine biosynthesis III
-
-
PWY-8359
TCA cycle I (prokaryotic)
-
-
TCA
TCA cycle II (plants and fungi)
-
-
PWY-5690
TCA cycle III (animals)
-
-
PWY66-398
TCA cycle IV (2-oxoglutarate decarboxylase)
-
-
P105-PWY
TCA cycle V (2-oxoglutarate synthase)
-
-
PWY-6969
TCA cycle VI (Helicobacter)
-
-
REDCITCYC
TCA cycle VII (acetate-producers)
-
-
PWY-7254
TCA cycle VIII (Chlamydia)
-
-
TCA-1
terminal O-glycans residues modification (via type 2 precursor disaccharide)
-
-
PWY-7434
tetracenomycin C biosynthesis
-
-
PWY-7485
tetradecanoate biosynthesis (mitochondria)
-
-
PWY66-430
tetrahydrofolate biosynthesis I
-
-
PWY-6614
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate
-
-
PWY-6613
tetrahydropteridine recycling
-
-
PWY-8099
tetrapyrrole biosynthesis I (from glutamate)
-
-
PWY-5188
theobromine biosynthesis I
-
-
PWY-5039
thiazole component of thiamine diphosphate biosynthesis I
-
-
PWY-6892
thioredoxin pathway
-
-
THIOREDOX-PWY
thiosulfate disproportionation IV (rhodanese)
-
-
PWY-5350
trans, trans-farnesyl diphosphate biosynthesis
-
-
PWY-5123
traumatin and (Z)-3-hexen-1-yl acetate biosynthesis
-
-
PWY-5410
trehalose degradation I (low osmolarity)
-
-
TREDEGLOW-PWY
trehalose degradation II (cytosolic)
-
-
PWY0-1182
trehalose degradation IV
-
-
PWY-2722
trehalose degradation V
-
-
PWY-2723
triacylglycerol degradation
-
-
LIPAS-PWY
tRNA charging
-
-
TRNA-CHARGING-PWY
tRNA methylation (yeast)
-
-
PWY-6829
tRNA processing
-
-
PWY0-1479
tRNA splicing I
-
-
PWY-6689
tRNA splicing II
-
-
PWY-7803
tRNA-uridine 2-thiolation and selenation (bacteria)
-
-
PWY-7892
tropane alkaloids biosynthesis
-
-
PWY-5317
trypanothione biosynthesis
-
-
TRYPANOSYN-PWY
tunicamycin biosynthesis
-
-
PWY-7821
type I lipoteichoic acid biosynthesis (S. aureus)
-
-
PWY-7817
type IV lipoteichoic acid biosynthesis (S. pneumoniae)
-
-
PWY-7818
UDP-alpha-D-galactofuranose biosynthesis
-
-
PWY-7622
UDP-alpha-D-galactose biosynthesis
-
-
PWY-7344
UDP-alpha-D-glucose biosynthesis
-
-
PWY-7343
UDP-N-acetyl-D-galactosamine biosynthesis II
-
-
PWY-5514
UDP-N-acetyl-D-galactosamine biosynthesis III
-
-
PWY-8013
UDP-N-acetyl-D-glucosamine biosynthesis I
-
-
UDPNAGSYN-PWY
UDP-N-acetyl-D-glucosamine biosynthesis II
-
-
UDPNACETYLGALSYN-PWY
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)
-
-
PWY-6387
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)
-
-
PWY-6386
UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)
-
-
PWY-7953
ultra-long-chain fatty acid biosynthesis
-
-
PWY-8041
UMP biosynthesis I
-
-
PWY-5686
UMP biosynthesis II
-
-
PWY-7790
UMP biosynthesis III
-
-
PWY-7791
urea cycle
UTP and CTP de novo biosynthesis
-
-
PWY-7176
UTP and CTP dephosphorylation I
-
-
PWY-7185
UTP and CTP dephosphorylation II
-
-
PWY-7177
valproate beta-oxidation
-
-
PWY-8182
vancomycin resistance I
-
-
PWY-6454
vanillin biosynthesis I
-
-
PWY-5665
very long chain fatty acid biosynthesis I
-
-
PWY-5080
very long chain fatty acid biosynthesis II
-
-
PWY-7036
vitamin K-epoxide cycle
wax esters biosynthesis II
-
-
PWY-5885
xanthine and xanthosine salvage
-
-
SALVPURINE2-PWY
xanthommatin biosynthesis
-
-
PWY-8249
xylitol degradation I
-
-
LARABITOLUTIL-PWY
xyloglucan degradation II (exoglucanase)
-
-
PWY-6807
zymosterol biosynthesis
-
-
PWY-6074
[2Fe-2S] iron-sulfur cluster biosynthesis
-
-
PWY-7250
(5R)-carbapenem carboxylate biosynthesis
-
-
PWY-5737
adipate degradation
-
-
PWY-8354
cis-vaccenate biosynthesis
-
-
PWY-5973
cyanate degradation
-
-
CYANCAT-PWY
dolichol and dolichyl phosphate biosynthesis
-
-
PWY-6129
folate polyglutamylation
-
-
PWY-2161
ketogluconate metabolism
-
-
KETOGLUCONMET-PWY
methylaspartate cycle
-
-
PWY-6728
myo-inositol biosynthesis
-
-
PWY-2301
octane oxidation
-
-
P221-PWY
urea cycle
-
-
PWY-4984
vitamin K-epoxide cycle
-
-
PWY-7999
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
784, 1148, 1996, 2572, 2573, 2578, 2579, 2580, 2581, 2582, 2583, 2587, 2588, 2791, 2850, 2858, 3097, 3999, 4003, 4026, 4031, 4046, 4632, 4955, 4958, 34777, 35231, 95003, 134779, 135294, 137330, 137344, 171171, 210262, 210605, 286903, 287012, 287356, 287900, 287901, 389446, 392696, 393965, 394780, 394782, 394803, 438159, 440015, 485045, 485374, 489711, 636664, 640451, 640452, 640516, 641288, 641312, 641426, 641517, 641544, 641572, 641578, 641606, 642286, 642288, 642469, 643502, 643650, 645461, 648773, 648774, 648775, 648776, 648777, 648778, 648779, 648780, 648781, 648782, 648783, 648972, 649134, 649652, 649717, 649760, 649857, 650135, 650149, 650980, 651858, 651896, 652192, 652307, 652398, 652750, 653042, 653217, 653869, 653889, 655266, 655670, 655915, 656470, 657211, 657390, 657645, 658546, 659297, 659311, 659462, 661039, 661742, 662276, 662286, 662323, 662337, 662636, 662797, 662799, 662808, 663245, 663547, 665665, 667525, 668467, 668604, 669585, 671153, 671381, 671727, 671933, 672414, 672608, 672817, 673409, 673414, 674757, 674786, 674811, 675307, 675809, 675870, 675891, 676067, 677097, 677098, 678178, 679129, 679729, 679738, 681278, 681566, 681818, 681820, 682002, 682787, 682829, 682836, 683025, 685567, 685820, 686025, 686094, 686656, 687755, 687787, 688829, 688893, 689043, 689056, 689059, 689246, 690940, 691064, 692329, 692365, 693090, 694074, 694537, 694917, 697000, 697252, 697338, 699998, 700280, 700501, 700875, 701584, 701648, 702559, 702570, 702691, 703220, 703221, 703505, 703514, 703519, 703682, 704603, 704833, 705557, 705604, 705608, 705609, 705789, 705970, 706402, 708330, 708449, 708953, 709517, 709568, 710348, 710429, 711463, 711751, 711756, 712042, 713060, 713502, 713772, 714875, 715854, 716252, 716265, 716905, 717284, 718790, 719226, 719934, 720195, 720405, 720558, 720892, 721030, 722149, 722365, 722415, 722722, 722758, 722871, 722966, 722967, 723172, 723219, 723221, 723808, 724770, 724891, 725417, 725472, 726002, 726096, 726861, 727139, 727329, 727946, 727951, 727974, 728026, 728337, 728395, 728551, 729623, 730355, 730795, 730906, 730931, 731956, 732011, 733611, 733944, 734572, 734614, 734654, 734656, 734824, 735017, 736501, 737319, 738144, 738158, 738969, 739471, 739542, 740099, 740404, 740994, 742867, 743060, 743268, 747666, 747683, 748625, 749153, 751562, 751632, 751793, 757395, 757637, 758156, 758656, 761829, 761960, 764698, 765448
-
-
-
390844, 489891, 645456, 649263, 651058, 652037, 652168, 652537, 655475, 656234, 665630, 671860, 671861, 675434, 677099, 679729, 687513, 689819, 699454, 700087, 705786, 708605, 727472, 728268, 738071, 738616, 739918, 740826
A8E112, B9WNA0, O76283, O97157, P39051, Q26820, Q381M1, Q382X3, Q385S9, Q388H8, Q38DJ3, Q6KBS8, Q6KF36, Q6UCJ6, Q6WZI6, Q7Z029, Q7Z1X2, Q86DE0, Q8ITL2, Q8WQX9, Q9GQU6, Q9GRG6, Q9NG18
SwissProt
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649919, 650031, 650207, 654952, 664015, 669002, 673410, 675433, 678177, 678377, 681295, 681448, 682576, 683194, 684992, 690232, 693367, 694072, 694881, 694946, 700501, 702148, 703193, 703682, 704488, 705176, 709103, 711604, 712697, 715578, 716670, 719382, 719908, 720501, 720806, 722346, 722964, 723131, 724281, 726097, 726398, 728811, 732089, 733294, 735220, 742196, 743569, 744439, 744840, 746175, 747666, 748671, 749523, 751633, 752230, 755173, 756231, 756513, 756675, 759064, 761745, 762255, 762567
A5HNV7, B9WNA1, C7AJA4, C9ZVV9, D0A003, D3HTY9, E3Q1H1, O15769, P04789, P07378, P07805, P31072, P50098, P86927, Q25B82, Q26710, Q27783, Q382P7, Q384Y1, Q385D6, Q386Y7, Q387Q3, Q388P2, Q389Z4, Q38A34, Q38AQ2, Q38AS1, Q38B76, Q38C91, Q38CB4, Q38DE2, Q38DZ5, Q38EH6, Q38F97, Q4DA54, Q57VZ2, Q57WJ1, Q57X12, Q57X81, Q57XC6, Q57ZH3, Q57ZL6, Q580G3, Q580M5, Q581U6, Q581U8, Q581W1, Q583R7, Q585M3, Q585M6, Q6R7Z5, Q7YW97, Q7Z032, Q86C09, Q8I8A5, Q95PL2, Q9NFL8
Uniprot
bifunctional enzyme with glutathionylspermidine synthase and trypanothione synthase activity
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bifuntional enzyme with dihydrofolate reductase and thymidylate synthase activity
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can be classified as DELTA4 desaturase due to its HX3HH motif; gene Tb10.6k15.3610
UniProt
editosome protein TbMP57, distinct from mitochondrial enzyme form, i.e. TbTUTase 108
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enzyme is not a RNA-dependent ribozyme, but may contain an RNA component
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isoform EK2, bifunctional choline kinase/ethanolamine kinase
UniProt
isozyme FRDg; soluble glycosomal and mitochondrial enzyme forms, the latter as 2 isozymes
SwissProt
isozyme FRDm1; soluble glycosomal and mitochondrial enzyme forms, the latter as 2 isozymes
SwissProt
isozyme FRDm2; soluble glycosomal and mitochondrial enzyme forms, the latter as 2 isozymes
SwissProt
MIT at 1.1, formerly designated 427-12/ICI-060, procyclic and bloodstream forms
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mitochondrial beta-ketoacyl synthase; ssp. brucei, strain 427, procyclic trypanosomes
SwissProt
PDI-2; two PDI enzyme forms, which contain one or two double-cysteine redox-active sites and correspond to a single domain PDI and a class 1 PDI, i.e. PDI-1 and PDI-2
SwissProt
RET1 and RET2, i.e. RNA editing TUTases 1 and 2, as components of different editing complexes
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strains 29-13 and TREU927/4, single gene Tb09.160.4300, identical in both strains
UniProt
subspecies Trypanosoma brucei rhodesiense strain STIB 900 and subspecies Trypanosoma brucei brucei strains LAB 110 EATRO and STIB 795
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the Trypanosoma brucei genome contains separate cytosolic and mitochondrial isoforms of TrpRS that are both required and have diverged in their respective tRNA recognition domains
UniProt
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
culture-adapted bloodstream and procyclic Trypanosoma brucei of cell line 449, descendants of the strain Lister 427, stably transfected with pHD449 encoding the tetracycline repressor
additional information
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784, 2791, 95003, 134779, 137330, 326380, 393965, 655670, 657390, 659297, 665665, 667525, 668467, 671381, 679729, 682002, 694074, 725475, 737319, 738143
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enzyme is expressed in both insect and mammalian bloodstream forms of Trypanosoma brucei
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PGKB and PGKC genes-encoding phosphoglycerate kinase are co-transcribed as part of a polycistronic RNA. PGKC mRNA and glycosomal PGKC protein are specific to bloodstream forms
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quantitative analysis of the expression of phosphoglycerate kinase in bloodstream form
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TbHK1 is essential to the bloodstream form. Silencing the gene for 4 days reduces cellular hexokinase about 60% and leads to parasite death
the cytosolic isoenzyme is the only isoform of malate dehydrogenase expressed in the bloodstream form
for RNA interference experiments a cell line (427 1313 514) is employed that encodes a second tetracycline repressor and constitutively expresses a T7-polymerase
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from insect and bloodstream, the latter enzyme form shows a 3fold higher activity
additional information
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bloodstream forms and procyclic forms of trypanosomes
additional information
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bloodstream-form Trypanosoma brucei RUMP528 (GPI-PLC-/-)
additional information
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both cytosolic and mitochondrial isozymes are more abundant in the insect stage, although they can be immunodetected in the bloodstream forms
additional information
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both isozymes appear to be clearly more abundant in the insect stage, although they can be immunodetected in the bloodstream forms
additional information
developmentally regulated expression of both PDI enzyme forms, the enzymes are not essential for growth of trypanosomes
additional information
in the parental 29-13 cells, enzyme TbSPPS is abundantly transcribed
additional information
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no activity in the bloodstream stage of the parasite
additional information
quantitative proteomic analysis show that the TbPAGM protein is present in both life cycle stages, procyclic and bloodstream forms
additional information
quantitative proteomic analysis show that the TbPMM protein is present in both life cycle stages, procyclic and bloodstream forms
additional information
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TbSTT3A transcribed in the bloodstream nor procyclic form
additional information
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TbSTT3B transcribed in the bloodstream nor procyclic form
additional information
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TbSTT3C not transcribed in the bloodstream nor procyclic form
additional information
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the enzyme is expressed in different life stages. Trypanosoma brucei brucei bloodstream form cell line S16 and the procyclic cell line 449
additional information
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transketolase activity is absent from the long slender bloodstream form of the parasite and the protein is not detectable in this life cycle stage, with the RNA present only at low abundance
additional information
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Trypanosomatids possess three different PARN genes, PARN-1, -2, and -3, each of which is expressed at the mRNA level in two life-cycle stages of the human parasite Trypanosoma brucei
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
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TbSIR2RP1 is a nuclear protein that colocalizes with telomeric sequences and minichromosomes
orphan kinesin TbKIN-D associates with cytoskeletal microtubules and is distributed throughout the cytoskeleton at all cell cycle stages
the enzyme is mainly cytosolic yet upon nutritional stress it redistributes and accumulates in stress granules colocalizing with the DEAD-box helicase TbDhh1
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additional information
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35231, 438159, 652036, 657390, 670186, 679729, 682002, 693367, 703682, 711604, 714876, 716265, 730355, 751633
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TbPLK trans-localizes from the flagellum attachment zone to the cytoplasm during anaphase
TbrPDEB2 is distributed between flagellum and cytoplasm
B9WNA0, F4NCC3, Q2KN28, Q2KN29, Q2KN30, Q381J5, Q386Y7, Q38CB4, Q4DA54, Q52MQ5, Q580R7, Q583R7, Q585M3, Q6PY95, Q9NDH8
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287012, 287900, 287901, 389446, 651157, 655915, 657211, 661698, 671381, 673792, 681566, 699998, 703682, 704488, 704833, 705786, 716156, 725417, 728329, 744439, 756231
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both cytosolic and mitochondrial isozymes are more abundant in the insect stage, although they can be immunodetected in the bloodstream forms
cytosolic isoenzyme is the only isoform of malate dehydrogenase expressed in the bloodstream form
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cytosolic isozyme, appears to be clearly more abundant in the insect stage, although it can be immunodetected in the bloodstream form
the enzyme is mainly cytosolic yet upon nutritional stress it redistributes and accumulates in stress granules colocalizing with the DEAD-box helicase TbDhh1
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under normal growth conditions, PP5 is primarily localized in the cytosol
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Cys347 is part of a peptide motif required for post-translational targeting of GPI-PLC to the endoplasmic reticulum
isozyme AK1, the 22 N-terminal amino acids are responsible for flagellum targeting. The flagellar targeting sequence of AK1 shares close similarity with that of calflagins. The flagellar localisation of AK1 persists throughout the Trypanosoma brucei life cycle, overview
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TbPLK trans-localizes from the flagellum attachment zone to the cytoplasm during anaphase
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TbrPDEB2 is distributed between flagellum and cytoplasm
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the enzyme is enriched at the anterior tip of the flagellum attachment zone
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2572, 2850, 2858, 4632, 4958, 287012, 287356, 287358, 640451, 640452, 641288, 645456, 669002, 673792, 675433, 681818, 719382, 722346, 728329, 730906, 738616, 740826, 758156, 758656
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gene contains PTS1-like targeting sequence for glycosomal localization
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in case of mutations on the endosome targeting motif, glycosomal GPI-PLC from Trypanosoma brucei fails to produce the glycosylphosphatidylinositol deficiency in Leishmania major
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N-terminal 18 amino acids of alpha-KDE1 contain overlapping mitochondrion- and peroxisome-targeting sequences and are sufficient to direct localization to the glycosome
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C7AJA4, O15769, Q2KN28, Q2KN29, Q2KN30, Q381J5, Q386Y7, Q38CB4, Q38DZ5, Q38F97, Q57X12, Q585M3, Q9NJQ8, Q9NJQ9, Q9XZJ9
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1996, 643502, 643503, 650982, 651858, 652036, 653217, 653869, 653889, 654200, 659311, 669002, 673792, 689043, 694241, 697000, 703682, 704488, 714876, 716905, 722964, 722966, 725472, 734656, 738144, 740404, 743268, 748671, 749153, 751633, 761829, 764698
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both cytosolic and mitochondrial isozymes are more abundant in the insect stage, although they can be immunodetected in the bloodstream forms
enzyme is down-regulated in bloddstream forms of Trypanosoma brucei
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isozyme TrpRS2 contains a mitochondrial targeting signal, two genes exist due to the need for a mitochondrial synthetase with extended substrate specificity to achieve aminoacylation of the imported thiolated and edited tRNATrp
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mitochondrial isozyme, appears to be clearly more abundant in the insect stage, although it can be immunodetected in the bloodstream form
predicted mitochondrial targeting sequence present at the N-terminus of TbRND
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the chaperones mtHsp70 and mtHsp40 and their cofactor Mge1 are uniformly distributed throughout the single mitochondrial network
the enzyme displays an exclusively mitochondrial localization
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the enzyme is composed of two proteins, protein PRORP2 is localized to the branched trypanosomatid mitochondrion and has a cleavable N-terminal targeting sequence
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the enzyme is composed of a catalytic RNA and two proteins, protein PRORP1 is largely confined to the single central nucleolus of the nuclei and only weak in the nucleoplasm
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642678, 655670, 657390, 675891, 677099, 681566, 698310, 700501, 703682, 706436, 751562, 756231, 762255
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with increase in growth temperature (up to 40°C) and geldanamycin treatment, PP5 translocates to the nucleus
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enzyme is translocated from glycosomes to the endoplasmic reticulum when cells are treated with mild alkaline or hypo-osmotic conditions
additional information
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analysis of subcellular localization of dUTPase, no localization in the mitochondrion or kinetoplast
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additional information
both enzyme forms co-localized with markers of the endocytic pathway and concentrate at the posterior end of the cell between the nucleus and the kinetoplast
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additional information
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endo-lysosomal system, wild-type, endosomal GPI-PLC from Trypanosoma brucei causes a deficiency of protein glycosylphosphatidylinositols in Leishmania major
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additional information
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integral editosome protein, distinct from mitochondrial enzyme form
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additional information
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most trypanosomal aminoacyl-tRNA synthetases are encoded by single-copy genes, suggesting the use of the same enzyme in the cytosol and mitochondrion
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additional information
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no localization to the nucleus, kinetoplast, basal bodies or to the flagellum
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additional information
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Separase is present in the cell during the entire cell cycle, but excluded from the nucleus until the metaphase-anaphase transition
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additional information
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the catalytically active cytosolic isozyme is toxic and lethal for bloodstream parasites
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additional information
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the enzyme contains a nuclear targeting sequence of 6 residues
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LINKS TO OTHER DATABASES (specific for Trypanosoma brucei)
SILVA: 16S/18S rRNA, 23S/28S rRNA
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Release 2023.1 (January 2023)
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