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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for protein-lipid-RNA complex
Gene ontology ID
GO:1990684
Definition
A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other
Comment
Examples of protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoprotein (HDL) and, to a lesser extent, low-density lipoprotein (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034364 'high-density lipoprotein particle' or GO:0034362 'low-density lipoprotein particle', which describe complexes of proteins and lipids only, without RNAs.
Synonyms
1. miRNA-lipoprotein complex
References
1. GOC: vesicles
2. PMID 21423178
3. PMID 22028337
4. PMID 23559634
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