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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for sumoylated E2 ligase complex
Gene ontology ID
GO:1990356
Definition
A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligase by a SUMO-activating E1 enzyme. Sumoylation of the target protein is either facilitated directly by the sumoylated E2 ligase or aided by an optional E3 ligase
Comment
An example of this is UBC9 in human (UniProt symbol P63279) in PMID:18691969 (inferred from direct assay).
References
1. GOC: bhm
2. PMID 18691969
3. IntAct: EBI-9347978
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