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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for prefoldin complex
Gene ontology ID
GO:0016272
Definition
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics
Synonyms
1. GIM complex
References
1. GOC: jl
2. PMID 17384227
3. PMID 24068951
4. PMID 9630229
5. Wikipedia: Prefoldin
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