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Gene ontology
Version 2014-12-22
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Details for Prp19 complex
Prp19 complex
Gene ontology ID
GO:0000974
Definition
A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p
Synonyms
1. nineteen complex
2. NTC
3. Prp19/CDC5 complex
References
1. GOC: krc
2. PMID 16540691
3. PMID 19239890
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