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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for large latent transforming growth factor-beta complex
Gene ontology ID
GO:0038045
Definition
A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors
Synonyms
1. large latent complex
2. LLC
References
1. GOC: bf
2. PMID 2350783
3. PMID 8680476
4. PMID 9805445
5. Reactome: R-HSA-177107
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