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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for Ku70:Ku80 complex
Gene ontology ID
GO:0043564
Definition
Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK
Synonyms
1. Ku70:Ku80 heterodimer
References
1. PMID 12518983
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