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Gene ontology
Version 2014-12-22
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Details for interleukin-12 complex
Gene ontology ID
GO:0043514
Definition
A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space
Comment
Note that this heterodimeric cytokine utilizes the IL-12p35 subunit as its alpha chain, which is also used by IL-35 as its alpha chain, and utilizes the IL-12p40 subunit as its beta chain, which is also used by IL-23 as its beta chain.
Synonyms
1. IL-12 complex
2. IL12A
3. IL12B
4. p35
5. p40
References
1. GOC: add
2. GOC: ebc
3. GOC: mah
4. PMID 12948519
5. PMID 1381512
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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