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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for transforming growth factor beta complex
Gene ontology ID
GO:0099126
Definition
A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerisation and dissociation of the LAP
Synonyms
1. TGF-beta complex
2. TGF-beta dimer
3. TGFB complex
4. TGFB dimer
5. TGFbeta complex
6. TGFbeta dimer
References
1. GOC: bhm
2. PMID 22943793
3. IntAct: EBI-12501958
4. IntAct: EBI-12502251
5. IntAct: EBI-12502440
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is a part of the parent element
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derives from the parent element
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