Any feedback?
Please rate this page
(ontology.php)
(0/150)

BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
169 different search results found


Details for GLI-SUFU complex
Gene ontology ID
GO:1990788
Definition
A protein repressing GLI's transcription factor activity when SMO signalling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins
Comment
An example of this is SUFU in human (Q9UMX1) in PMID:24311597 (inferred from direct assay).
References
1. GOC: bhm
2. PMID 24311597
3. IntAct: EBI-10170144
4. IntAct: EBI-10828915
5. IntAct: EBI-10828948
6. IntAct: EBI-10828976
7. IntAct: EBI-10828997
8. IntAct: EBI-10829035
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
Tree view
Gene ontology