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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for TSC1-TSC2 complex
Gene ontology ID
GO:0033596
Definition
A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway
Synonyms
1. tuberin-hamartin complex
2. tuberous sclerosis complex
References
1. PMID 10585443
2. PMID 17121544
3. PMID 9580671
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