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Gene ontology
Version 2014-12-22
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Details for [methionine synthase] reductase activity
1.16.1.8
Gene ontology ID
GO:0030586
Definition
Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+
Comment
Note that this was EC:2.1.1.135.
Synonyms
1. 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
2. [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity
3. methionine synthase cob(II)alamin reductase (methylating) activity
4. methionine synthase reductase activity
5. methionine synthase-cobalamin methyltransferase (cob(II)alamin reducing)
6. methionine synthase-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase activity
References
1. EC 1.16.1.8
2. MetaCyc 2.1.1.135-RXN
3. Reactome: R-HSA-3149518 "MTRR reduces cob(II)alamin to meCbl"
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