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Gene ontology
Version 2014-12-22
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Details for cholesterol 7-alpha-monooxygenase activity
1.14.14.23
Gene ontology ID
GO:0008123
Definition
Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O
Synonyms
1. cholesterol 7-alpha-hydroxylase activity
2. cholesterol 7alpha-hydroxylase activity
3. cholesterol 7alpha-monooxygenase activity
4. cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)
5. cytochrome P450 CYP7A1
References
1. EC 1.14.14.23
2. MetaCyc CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN
3. Reactome: R-HSA-192051 "CYP7A1 7-hydroxylates CHOL"
4. RHEA: 21812
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